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  • Anaplastic carcinoma of the thyroid  (1)
  • Bone marrow plasmocytosis  (1)
  • 1
    ISSN: 1432-2307
    Keywords: Anaplastic carcinoma of the thyroid ; Haemangioendothelioma ; Immunohistology ; Coexpression of epithelial and vascular antigens
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Sixteen cases of anaplastic carcinoma (ACA) and 4 cases of malignant haemangioendothelioma (HAE) of the thyroid were studied by light microscopy and immunohistochemistry. Seven cases of ACA and 3 cases of HAE were characterized by coexpression of immunohistological features of epithelial and vascular endothelial cells. Expression of vimentin was common to all tumours investigated. The present study provides evidence that ACA and HAE are partially closely related tumours showing alternating differentiation. This speaks in favour of a common neoplastic cell with the potential for epithelial and vascular endothelial differentiation.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Annals of hematology 53 (1986), S. 11-19 
    ISSN: 1432-0584
    Keywords: Bone marrow plasmocytosis ; Monoclonal plasma cells ; Polyclonal plasma cells
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Bone-marrow biopsies and smears from 59 patients with reactive plas-mocytosis (22), multiple myeloma (24), solitary plasmocytoma (3) and monoclonal gammopathy of undetermined significance (MGUS) (10) were eamined. To demonstrate cytoplasmic immunoglobulin the immunoperoxidase method was applied and evaluated quantitatively. Immunohistology yielded different ranges in κ/λ ratio for reactive plasmocytosis (0.4–3.5), multiple myeloma (≤ 0.1 and ≥ 11.2) and MGUS (0.2–3.0). As a result this method seems to be helpful in characterizing a plasmocytosis and distinguishing overt myeloma from monoclonal gammopathy of undetermined significance and reactive plasmocytosis. A differentiation of monoclonal gammopathy of undetermined significance from reactive plasmocytosis is not possible histologically and immunohistologically.
    Type of Medium: Electronic Resource
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