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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 59 (1981), S. 567-569 
    ISSN: 1432-1440
    Keywords: Nomifensine ; Immune haemolytic anaemia ; Renal failure ; Nomifensin ; Immuhämolytische Anämie ; Nierenversagen
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Wir berichten über zwei Fälle von immunhämolytischer Anämie und akutem Nierenversagen nach Nomifensineinnahme. Die beiden Patientinnen hatten wegen reaktiver Depressionen eine kontinuierliche Nomifensintherapie erhalten. In beiden Fällen war das Nomifensin zwischenzeitlich abgesetzt worden, und die klinischen Reaktionen — immunhämolytische Anämie und Nierenversagen — traten unmittelbar nach erneuter Einnahme einer Kapsel dieses Präparates auf. In einem Fall enthielt das Serum der Patientin einen potenten Antikörper, der in Gegenwart von Nomifensin ihre eigenen Erythrozyten im Antiglobulin-Test agglutinierte.
    Notes: Summary Two cases of immune haemolytic anaemia and acute renal failure induced by nomifensine are reported. The two female patients had been under continous nomifensin therapy because of reactive depressions. In both cases nomifensine had been discontinued and the clinical reactions — immune haemolytic anaemia and acute renal failure — started immediately after they had taken again a capsule of nomifensine. In one case the patient's serum contained a potent antibody which agglutinated her red blood cells in presence of nomifensine in the antiglobulin test.
    Type of Medium: Electronic Resource
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