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  • 1
    ISSN: 1432-5233
    Keywords: Apolipoprotein gene ; Restriction fragment length polymorphism ; Non-insulin-dependent diabetes mellitus ; Coronary heart disease
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The aim of this study was to verify whether or not the increased prevalence of coronary heart disease (CHD) commonly observed in patients with type 2 diabetes mellitus is related to a genetic background involving restriction fragment length polymorphisms (RFLPs) of apolipoproteins. On the basis of a case-control design, 62 type 2 diabetic patients with CHD (confirmed by clinical history and electrocardiogram) and 62 age- and sexmatched diabetic subjects without CHD were enrolled. In each of them RFLPs of the apolipoprotein CIII gene (S1 or S2 allele) and AI promoter region (A or G allele), together with fasting plasma lipids and apolipoproteins levels, were assessed. The rare S2 allele was found significantly (P=0.05) more frequently in patients with CHD, and its related S1S2 genotype was associated with higher plasma levels of total cholesterol (P=0.01), triglycerides (P=0.007) and apo B (P=0.001) than the S1S1 genotype. The A allele was more frequent (P=0.004) in patients without CHD and was associated with lower plasma cholesterol (P=0.0001), low-density lipoprotein (LDL)-cholesterol (P=0.0001) and apo B (P=0.005). The S1/A haplotype was more frequent (P=0.05) in patients without CHD and was associated with the lowest plasma lipid levels. These results suggest that genetic factors, related to the apo AI-CIII-AIV gene cluster, could play a role in the development of CHD in type 2 diabetic patients, probably through modification of their plasma lipid pattern.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    New York : Wiley-Blackwell
    Journal of Polymer Science: Polymer Physics Edition 11 (1973), S. 2291-2295 
    ISSN: 0098-1273
    Keywords: Physics ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    New York : Wiley-Blackwell
    Journal of Polymer Science: Polymer Physics Edition 23 (1985), S. 2109-2118 
    ISSN: 0098-1273
    Keywords: Physics ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: Stress-induced crystallization of a crosslinked polybutadiene with a high 1,4-cis content is investigated, at room temperature. The change in the fraction of crystallinity with deformation is evaluated by two different methods. The first is based on simultaneous measurement of birefringence and stress. The second is based on calorimetric analysis. The data on crystallinity obtained by these two methods are in good agreement in the range of low deformations, while, in the range of higher deformation (λ 〉 5), the degree of crystallinity obtained by calorimetry is higher than that obtained by the optical method. Qualitative information on the crystallization was also obtained by optical analysis of the hysteresis behavior. The hysteresis data show the presence of ordering phenomena at deformations at which there seems to be no crystallinity according to both quantitative methods.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    New York : Wiley-Blackwell
    Journal of Polymer Science: Polymer Physics Edition 20 (1982), S. 1525-1531 
    ISSN: 0098-1273
    Keywords: Physics ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: Stress-induced crystallization of natural rubber networks is studied. The analysis is carried out using two different experimental techniques and the results are compared. In particular, the microcalorimetric and photoelastic results seem to be in disagreement, but the disagreement can be resolved by assuming that organization phenomena take place even at strains less than the critical value at which thermally detectable crystallization occurs. It is believed that such organization phenomena give rise to highly defective crystallites which behave as nucleation agents in the crystallization process that is induced at larger strains.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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