Library

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Phytochemistry 21 (1982), S. 1759-1762 
    ISSN: 0031-9422
    Keywords: Aristolochia manshuriensis ; Aristolochiaceae ; aristolochic acid derivatives ; aristolochic acid glucoside ; aristolochic acids I, IV, and -D. ; aristoloside ; stem
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    ISSN: 1432-0827
    Keywords: PTHrP ; Articular cartilage ; Chondrocyte ; Development
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Abstract Expression and localization of parathyroid hormone-related protein (PTHrP) in rat articular cartilage during fetal and postnatal periods were investigated by immunohistochemistry and in situ hybridization. PHTrP displayed distinct distribution and intensity of staining at different ages. In fetal (18-day-old) and young (3-week-old) rats, articular chondrocytes expressed abundant PTHrP throughout the entire thickness of cartilage. In contrast, in 60-week-old rats, PTHrP was expressed in a few articular chondrocytes of superficial and middle layers. Regulation of PTHrP and PTH/PTHrP receptor mRNA was also studied in cultured rat articular chondrocytes. Northern blot analysis revealed that both transforming growth factor-β (TGF-β), an important stimulator for chondrocyte proliferation and differentiation, and 10% fetal bovine serum (FBS) stimulated the expression of PTHrP mRNA with down-regulation of its receptor mRNA. In contrast, 12-O-tetradecanoylphorbol-13-acetate (TPA) down-regulated the expression of receptor without changes of PTHrP mRNA level. These results suggest that the changes in abundance and localization of PTHrP and its receptor may be directly involved in the cell growth and differentiation of articular cartilage.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    Electronic Resource
    Electronic Resource
    Springer
    International orthopaedics 6 (1982), S. 141-148 
    ISSN: 1432-5195
    Keywords: Perthes' disease ; Intraosseous venography ; Intramedullary pressure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé On a réalisé des phlébographies intra-osseuses et mesuré la pression intra-médullaire au niveau de la métaphyse chez 55 patients atteints d'une maladie de Perthes unilatérale. L'irruption du produit opaque dans la diaphyse constitue le signe le plus important au cours de la phlébographie osseuse métaphysaire. Elle s'accompagne d'une élévation de la pression intramédullaire, ce qui traduit l'existence d'une congestion veineuse métaphysaire. Comme cette congestion s'observe aussi bien au stade de sclérose qu'à celui de segmentation, elle ne peut préjuger de la gravité de la maladie, selon la classification de Catterall [1]. La congestion veineuse peut jouer un rôle dans la pathogénie de la maladie de Perthes, mais le pronostic relève probablement de facteurs différents.
    Notes: Summary Intraosseus venography and measurement of intramedullary pressure have been carried out in the metaphyses of 55 patients with unilateral Perthes' disease. Flow of the opaque medium into the diaphysis is the most important finding in intraosseous venography of the metaphysis. This was related to a rise of intramedullary pressure which indicates the presence of venous congestion within the metaphysis. While such congestion was seen both in the sclerotic stage and the segmentation stage, it was not related to the severity of Perthes' disease as judged by Catterall's [1] classification. Such venous congestion could be relevant to the pathogenesis of Perthes' disease, but there are probably different factors which determine the prognosis.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...