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  • Postmortem  (2)
  • Aspergillosis  (1)
  • Hautwunden  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Usefulness of myosin in the postmortem diagnosis of myocardial damage (1995)
    Springer
    International journal of legal medicine 108 (1995), S. 14-18 
    Details
    ISSN: 1437-1596
    Keywords: Myocardial ischaemia ; Biochemistry Myosin ; Postmortem ; Pericardial fluid
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Notes: Abstract In some situations the postmortem diagnosis of myocardial infarction is made difficult by the brief course of the fatal episode or by interferences caused by autolysis. In such cases, biochemical indices may provide a useful adjunct to morphological studies. Myosin is the main component of the contractile apparatus of muscle cells, so its determination may well be useful to evaluate myocardial injury. The purpose of the present study was to establish the diagnostic efficacy of postmortem myosin heavy chain determinations using monoclonal antibodies and to compare this data with structural findings used to diagnose acute myocardial ischaemia. We studied 105 cadavers with a mean age of 61.63 ± 2.21 years. Cases were allocated to 1 of 7 diagnostic groups depending on the probable intensity of myocardial damage and cause of death. The highest serum and pericardial fluid values of myosin heavy chains were seen in subjects who showed morphological evidence of myocardial ischaemia. Mean pericardial fluid/serum ratios differed significantly between subjects with and without observable signs of heart damage.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01845610
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Lipid peroxidation in lung tissue after chest trauma and correlation with the duration of the post-trauma survival period (1998)
    Springer
    International journal of legal medicine 111 (1998), S. 256-260 
    Details
    ISSN: 1437-1596
    Keywords: Key words Chest trauma ; Lipid peroxidation ; Reperfusion ; Lung ; Postmortem
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Notes: Abstract Blunt chest trauma is a frequently encountered cause of death in forensic pathology and one of the organs most likely to be affected are the lungs. Assuming that the victim survives the initial trauma, reperfusion processes take place, free radicals are formed and lipid peroxidation occurs. The aim of this study was to ascertain whether the length of the survival time is correlated with the extent of lipid peroxidation in the lung tissue following such ischaemia-reperfusion processes. A study of 470 samples taken from all five pulmonary lobes from 94 cadavers was carried out. Cases were allocated to different groups according to whether there was chest trauma and/or a known survival period. Lipid peroxidation was investigated by determining malondialdehyde (MDA) levels. The lowest mean level of peroxidation was found in control cases showing no evidence of chest trauma at autopsy and no apparent survival period. Our results suggest that the level of lipid peroxidation in lung tissue can be a reliable indicator of survival processes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004140050164
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Prostaglandin F2a (PGF2a): an inadequate marker of the vitality of wounds? (1994)
    Springer
    International journal of legal medicine 106 (1994), S. 312-314 
    Details
    ISSN: 1437-1596
    Keywords: Prostaglandin F2a ; Skin wounds ; Vitality diagnosis ; Prostaglandin F2a ; Hautwunden ; Vitalitätsdiagnose
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Description / Table of Contents: Zusammenfassung Die Verwendbarkeit von Prostaglandin F2a als Vitalitätsmarker wurde an Hautverletzungen studiert. Als Material dienten 20 vitale Schnittverletzungen sowie entsprechende Kontrollen unverletzter Haut aus 20 Obduktionsfällen des Instituts für Rechtsmedizin der Universität Coimbra (Portugal). Weiter wurden 10 frische Hautproben von Patienten der Dermatologischen Abteilung des Klinikums Granada untersucht. Die Prostaglandin-Analysen wurden mittels RIA durchgeführt. Die Ergebnisse belegen, daß die Bestimmung des (PGF2a): nicht als Methode des Vitalitätsnachweises von Wunden geeignet ist.
    Notes: Summary We have studied the viability of (PGF2a): as a vitality marker in skin wounds. Incised vital skin wounds and homolateral control pieces of skin were obtained from 20 autopsies performed at the Institute of Legal Medicine of Coimbra University (Portugal). We have also studied 10 fresh skin samples from the Department of Dermatology of the University Hospital (Granada). Our results show that (PGF2a): is not suitable for the diagnosis of the vitality of wounds because of its irregular behaviour.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01224777
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Invasive pulmonary aspergillosis after near-drowning (1984)
    Springer
    Intensive care medicine 10 (1984), S. 203-204 
    Details
    ISSN: 1432-1238
    Keywords: Near-drowning ; Aspergillosis ; Respiratory failure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract After near-drowning following a car accident, a 27-year-old man developed servere ARDS. Six days later Aspergillus fumigatus was isolated in his sputum, and invasive pulmonary aspergillosis developed thereafter. Aspergillus titre increased, and chest tomograms revealed cavities in both lungs. The treatment consisted essentially of Amphotericin B and 5 fluorocytosine, intravenously and by inhalation, intensive postural drainage and mechnical ventilation with PEEP. After 41 days he was cured and discharged from the ICU. Six months later he returned to his job and clinical examination was normal.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00259439
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    Paper (German National Licenses)
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