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  • 1
    ISSN: 1432-0533
    Keywords: Asphyxia ; Circulatory arrest ; Tegmental necrosis ; Spinal cord ; Perinatal period
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary This study reports subcortical lesions in 7 newborn babies after transient circulatory arrest and/or asphyxia. Basal ganglia, diencephalon, tegmentum of the brain stem and spinal grey matter exhibited extensive necroses in a columnar pattern. The lesions of the telencephalic and cerebellar cortex are less prominent. The spinal cord, available in 3 children, revealed subtotal neuronal loss in all segments. The lesions represent the extreme anoxic damage of the CNS in the perinatal period, comparable with brain death in the adulthood. Moreover, the pattern with predominating subcortical lesions indicates that anoxia affects the grey matter in all levels of the CNS.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Clinical and experimental medicine 153 (1970), S. 95-98 
    ISSN: 1591-9528
    Keywords: Neurosecretion ; Carbamazepine ; Histochemistry ; Neurosekretion ; Carbamazepin ; Histochemie
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die Enzyme TPP, NADPH2-D, G6PDH und sPh ließen sich bei Ratten im osmotischen Streß in erhöhter Aktivität nachweisen. Längerer Wasserentzug führte bei den Tieren zu einem fast völligen Schwinden des Neurosekretes. Die Gabe von Carbamazepin hatte weder einen Einfluß auf die Enzymaktivitäten noch auf die Neurosekretproduktion. Die Befunde sprechen dagegen, daß Carbamazepin am Bildungsort des ADH wirksam wird.
    Notes: Summary Due to an osmotic stress rats showed an increased activity of the enzymes thiaminphosphatase, acid phosphatase, NADPH2-diaphorase and glucose-6-phosphat-dehydrogenase in their neurosecretory nuclei. Carbamazepine did not influence these enzyme activities neither in thursting rats nor in those fed regularly. Its antidiuretic effect can therefore not he explained by stimulation of the nucleus supraopticus or paraventricularis.
    Type of Medium: Electronic Resource
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