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  • Cell & Developmental Biology  (2)
  • Autonome Hyperreflexie  (1)
  • Defekt-Polymer  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Autonome Hyperreflexie, Schwangerschaft und Entbindung bei Para-/Tetraplegie Geburtshilflich-anästhesiologische Gesichtspunkte anhand einer Kasuistik (1996)
    Springer
    Der Anaesthesist 45 (1996), S. 1179-1183 
    Details
    ISSN: 1432-055X
    Keywords: Schlüsselwörter Querschnittslähmung ; Autonome Hyperreflexie ; Geburtshilfliche Anästhesie ; Periduralanalgesie ; Key words Obstetric anaesthesia ; Epidural analgesia ; Autonomous hyperreflexia ; Spinal cord injury
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Abstract Although still rare, pregnancy and delivery in women with spinal cord injuries is becoming more frequent (Table 2). In 85%–90% of patients with lesions above T6 symptoms of autonomic hyperreflexia (Table 1), especially paroxysmal and excessive increases in arterial blood pressure, may occur. In anaesthesising a 31-year-old paraplegic primigravida with a complete transverse spinal lesion at T4 for an elective caesarean section, no indication of hypertonic cardiovascular dysregulation either intra- or postoperatively was observed after repeated epidural administration of bupivacaine. Distinct intraoperative spasticity of the abdominal wall muscles was, however, not influenced by the dosages selected.
    Notes: Zusammenfassung Es wird berichtet über das geburtshilflich-anästhesiologische Vorgehen und den peripartalen Verlauf bei einer 31jährigen Erstgravida mit traumatischer Querschnittsläsion in Höhe Th 4 und klinischen Zeichen einer autonomen Hyperreflexie (AH). In der 37. Schwangerschaftswoche erfolgte eine primäre Sectio caesarea aus kindlicher Indikation. Hypertone Kreislaufdysregulationen im Rahmen von AH-Attacken wurden unter repetitiver Bupivacainanwendung über einen Periduralkatheter nicht beobachtet, eine ausgeprägte intraoperative Spastik der Bauchdeckenmuskulatur war mit den gewählten Dosen allerdings nicht zu beeinflussen.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001010050355
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  • 2
    Electronic Resource
    Electronic Resource
    Fibrinogen derivatives with a higher molecular weight than that of the parent molecule in cord vein plasma of newborns (1973)
    Springer
    Journal of molecular medicine 51 (1973), S. 699-702 
    Details
    ISSN: 1432-1440
    Keywords: Agarose gel filtration ; PAA gel electrophoresis in urea ; fibrinogen derivatives ; fibrinogen fibrinmonomer complex ; defect polymer ; Agarose-Gel-Filtration ; PAA-Gel-Elektrophorese in Harnstoff ; Fibrinogenderivate ; Fibrinogen-Fibrinmonomer-Komplex ; Defekt-Polymer
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Das Auftreten zweier Fibrinogenderivate mit höherem Molekulargewicht als dem des Fibrinogens im Nabelvenenplasma asphyktischer Neugeborener konnte in dieser Studie bestätigt werden. Nachdem aus Einzelproben ein Pool gebildet worden war, wurde dieser der Agarose-Gel-Filtration unterworfen, und anschließend wurden die eluierten Proben elektrophoretisch untersucht. Elektrophoresen in 5 Mol Harnstoff deuteten darauf hin, daß das 0,27 Derivat ein Komplex ist, der sich vorwiegend aus untereinander nicht kovalent gebundenen Komponenten zusammensetzt und der in 5 Mol Harnstoff dissoziiert. Möglicherweise entsteht dieser Komplex (Fibrinogen-Fibrinmonomer-Komplex) durch die Wirkung von Thrombin auf Fibrinogen. Das 0,17 Derivat setzt sich vorwiegend aus untereinander kovalent gebundenen Komponenten zusammen. Es könnte sich hierbei um ein Plasminderivat quervernetzten Fibrins (Defekt-Polymer) handeln.
    Notes: Summary The occurrence of two fibrinogen derivatives with a molecular weight higher than that of the parent molecule in cord vein blood of asphyctic newborns was confirmed in this study. Agarose gel filtration and electrophoresis of the eluted fractions were performed from pooled plasma. Electrophoretic studies in the presence of 5 M urea indicated that the 0.27 derivative is a complex formed of predominantly non covalently linked components, which dissociates in the presence of 5 M urea. It might be assumed that this derivative (fibrinogenfibrinmonomer complex) results from the action of thrombin on fibrinogen. The 0.17 derivative consists of predominantly covalently linked components. It might be originated from the action of plasmin on stabilized fibrin (defect polymer).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01468358
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  • 3
    Electronic Resource
    Electronic Resource
    A light and electron microscopic study of the pineal gland of the ground squirrel, Citellus tridecemlineatusSupported by A. D. Williams 3558 (509) and 3558 (505), Medical College of Virginia. (1975)
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 143 (1975), S. 465-483 
    Details
    ISSN: 0002-9106
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The pineal gland of the 13-lined ground squirrel (Citellus tridecemlineatus) has been examined at the light and electron microscopic level. This gland is composed of low-density parenchymal cells interspersed among which are occasional glial, vascular and neural elements. Punctuating the glandular parenchymal mass are prominent perivascular and intercellular spaces.The parenchymal cells possess numerous mitochondria and less prominent profiles of rough and smooth-surfaced endoplasmic reticulum. Golgi apparatus, microtubules and lipid droplets of varying size and electron density constitute regular cytoplasmic features, with dense-core vesicles being present occasionally. The parenchymal cells have numerous processes. One among these in each cell extends for several micra to terminate in a bulbous expansion containing both clear and dense-core vesicles and occasional electron-dense inclusions. These bulbous terminals are found within the perivascular and intercellular spaces where they course in close proximity to both other parenchymal elements and axon terminals. Glial cells and their processes invest the pineal periphery and incompletely separate the parenchymal cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aja.1001430405
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Electron microscopic changes following canine cardiac allografts: The effects of irradiation (1970)
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 129 (1970), S. 169-175 
    Details
    ISSN: 0002-9106
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Orthotopic cardiac allotransplantation was performed on ten adult mongrel dogs. At the time of acute rejection (decline in QRS voltage to at least onehalf of the post-operative level) a cardiac biopsy was removed from the left ventricle of each dog and followed by 300 r of local x-irradiation on five consecutive days. After a full course of x-irradiation (1500r) to each dog a second biopsy was removed from the left ventricle. In this way, each dog acted as its own control in order to determine the effects of x-irradiation on cardiac transplants and the rejection phenomenon. The electron microscopic findings at the time of acute rejection involved primarily the myocytes and their cellular organelles in that the A, I, and Z bands were less distinct and there was significant enlargement and cytological distortion of the mitochondria, endoplasmic reticulum and T tubules. Endothelial hyperplasia of the smaller blood vessels was also more apparent in the pre-irradiation biopsies. Following irradiation the ultrastructural changes appeared to be reversed in six of the ten dogs; mitochondria and other organelles of the myocytes were more normal and the banding of the fibers was more distinct. Vascular alterations were less and the tissue approached normal cytological architecture. Pre- and post-irradiated cardiac tissues were not different in two animals and in two other animals the post-irradiated tissues appeared more abnormal than those showing acute rejection. Local irradiation as a method of immunosuppression in cardiac transplants is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aja.1001290204
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