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  • 1
    Electronic Resource
    Electronic Resource
    Autopsy findings in AIDS — A histopathological analysis of fifty cases (1987)
    Springer
    Journal of molecular medicine 65 (1987), S. 654-663 
    Details
    ISSN: 1432-1440
    Keywords: AIDS ; Autopsy ; Histopathology ; HIV ; Opportunistic infections
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Fifty consecutive AIDS autopsy cases were evaluated. All subjects showed one or more opportunistic infections and malignancies included in the AIDS case definition with cytomegalovirus and Kaposi's sarcoma being most prevalent. Mycobacterial and cryptococcal infections occurred only infrequently. Most patients of our series after successful treatment ofPneumocystis carinii pneumonia or cerebral toxoplasmosis later succumbed to less treatable conditions like disseminated cytomegalovirus or fungal infections or malignant lymphoma. In the absence of specific treatment for the HIV infection leading to these lethal complications special emphasis must be put on the prevention of HIV transmission and spread.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01875500
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Palmar fibromatosis (Dupuytren's contracture) (1984)
    Springer
    Virchows Archiv 405 (1984), S. 41-53 
    Details
    ISSN: 1432-2307
    Keywords: Fibromatosis ; Dupuytren's contracture ; Myofibroblast ; Ultrastructure ; Histochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Forty three cases of palmar fibromatosis were studied by light and electron microscopy, enzyme histochemistry, and ultrastructural immunohistochemistry. By electron microscopy most of the cells composing the nodules in both the proliferative and the involutional stages were identical to myofibroblasts. The myofibroblasts in the involutional nodules often possessed microfilament aggregates probably representing contraction of micro(actin)fllaments in the cytoplasm. The proliferative nodules revealed small perivascular haemorrhages and haemosiderin deposits accompanied by accumulation of macrophages and some lymphocytes; these inflammatory cells possibly secrete a certain growth factor inducing proliferation of genetically abnormal fibroblasts and myofibroblasts. Diaminopeptidase IV was detected in myofibroblasts and fibroblasts by enzyme histochemistry and ultrastructural immunohistochemistry; the enzyme may play a role in the metabolism of intercellular substances. Some perivascular mesenchymal cells, interpreted as variants of myofibroblasts, had moderate activity of alkaline phosphatase.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00694924
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Splenic erythropoiesis in rats under hypoxic and post-hypoxic conditions (1986)
    Springer
    Virchows Archiv 409 (1986), S. 251-261 
    Details
    ISSN: 1432-2307
    Keywords: Erythrophagocytosis ; Erythropoiesis ; Hypoxia ; Splenic red pulp
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In rats chronic hypoxia causes extramedullary haematopoiesis mainly localized in the spleen. It is not known how splenic erythropoiesis develops and how it regresses after termination of hypoxia. In this study the spleen of rats exposed to chronic hypoxia was studied by light and electron microscopy; the findings were compared to relevant peripheral blood values. Splenic erythropoiesis begins almost immediately after exposure to hypoxia and reaches its maximum after 24 weeks. It occurs mainly in the splenic cords drawing upon local erythroblasts and is accompanied by an increase in splenic weight as well as a decrease in splenic iron stores. After termination of hypoxia marked phagocytosis by splenic cord macrophages diminishes the number of erythroblasts and of erythrocytes with a concomitant increase in splenic iron stores. Thus, splenic erythropoiesis appears to be inhibited as part of a rebound phenomenon and returned to normal by phagocytosis of erythroid cells within 4 weeks after cessation of the hypoxic stimulus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00708332
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Interdigitating cells in the white pulp of the human spleen (1974)
    Springer
    Cell & tissue research 153 (1974), S. 415-417 
    Details
    ISSN: 1432-0878
    Keywords: Spleen (human) ; Periarteriolar lymphocytic sheath ; Reticular cell ; Enzyme histochemistry ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Interdigitating cells are demonstrated as a special type of fixed cell in the periarteriolar lymphocytic sheaths of the human spleen. These cells show typical ultrastructural features as well as a characteristic enzyme histochemical pattern that distinguish them from other reticular cells in the splenic white pulp.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00229168
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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