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  • 1
    Electronic Resource
    Electronic Resource
    RECEPTOR LOCALIZATION BY AUTORADIOGRAPHIC TECHNIQUES (1967)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 144 (1967), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1967.tb53808.x
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  • 2
    Electronic Resource
    Electronic Resource
    Low-Temperature Fluorography Induced by Tritium-Labelled Compounds on Thin-Layer Chromatograms (1965)
    [s.l.] : Nature Publishing Group
    Nature 205 (1965), S. 1190-1191 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] AUTORADIOGRAPHIC methods have not yet found /JL application to thin-layer chromatography of 3H-labelled compounds because of the low tritium energy (Emax = 18-5 keV; Emean = 5-7 keV). The tritium range in a layer of sodium-o-(carboxymethyl) cellulose and in sodium alginate has been determined by ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/2051190a0
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  • 3
    Electronic Resource
    Electronic Resource
    Autoradiography of End-plates with Carbon-14 – Calabash – Curarine I and Carbon-14 – Decamethonium (1956)
    [s.l.] : Nature Publishing Group
    Nature 178 (1956), S. 981-981 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] For this purpose we had to synthesize carbon-14 -curarine of the highest possible radioactivity by methylation of 2.0 mgm. nor-curarine with an excess of 6.4 mgm. 14CH3I, having the activity of 1 me. After recrystallization we obtained 0-25 mgm. pure carbon-14 - curarine - iodide (biquaternary) ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/178981a0
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  • 4
    Electronic Resource
    Electronic Resource
    The influence of taipoxin on cholinergic synapses in the electric organ ofTorpedo Marmorata (1978)
    Springer
    Journal of neural transmission 42 (1978), S. 263-273 
    Details
    ISSN: 1435-1463
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The influences of the snake venom taipoxin on the cholinergic synapses of the electric organ ofTorpedo marmorata were investigated. 1. In ultrathin sections presynaptic membrane indentations are noted under the influence of taipoxin/NaCl. 2. The presynaptic membranes often show small interruptions. 3. In taipoxin/horseradish peroxidase incubated organ pieces typical omega-shaped indentations are found, but on the postsynaptic side. 4. The vesicle density decreased under the influence of the taipoxin in contrast to untreated cholinergic synapses. 5. In freeze etched preparations no membrane indentations and interruptions are observed, but only a small vesicle density was seen.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01673551
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  • 5
    Electronic Resource
    Electronic Resource
    Zur Kenntnis des Muscarins (1954)
    Springer
    Cellular and molecular life sciences 10 (1954), S. 298-300 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The alkaloid muscarin was isolated from fly agaric. The analyses of crystallized salts (chloride, tetra-chloroaurate,Reinecke's salt) led to C9H20O2N+ as the simplest formula. The presence of aldehyde and tri-methyl-ammonium groups, which had been assumed hitherto, could not be proved. The quaternary nature of the nitrogen atom was shown. Pharmacological tests on frog heart, rabbit gut and cats show the purely peripheral parasympathomimetic effect of the smallest doses.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02158738
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  • 6
    Electronic Resource
    Electronic Resource
    Struktur und Wirkung des Muscarins, des Muscarons und ihrer Stereoisomeren (1958)
    Springer
    Cellular and molecular life sciences 14 (1958), S. 356-358 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary All synthetic isomers of (+)-muscarine, the racemic forms of epi-muscarine, allo-muscarine, and epiallo-muscarine are at least 100 times less potent on blood pressure of cats and isolated frog hearts than the natural alkaloid. Only muscarones are more potent and exhibit strong nicotinic action on the frog rectus and in blocking ganglionic and neuro-muscular transmission in the cat. They closely resemble acetylcholine in their structure and action. The activity of the isomers depends on the position of the constituents on the tetrahydrofurane ring. Steric hindrance of the hydroxy or carbonylgroup and of etheroxygen plays an important part in the contact with the cholinergic receptor. As nor-muscarine without the quarternary nitrogen is inactive, at least 3 different points of contact have to be considered. This is stressed by the fact that muscarine is highly stereospecific in its action, whereas muscarone is not.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02159151
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  • 7
    Electronic Resource
    Electronic Resource
    Der Einfluss verschiedener Psychopharmaka auf den Bluthistamingehalt von Ratten (1959)
    Springer
    Cellular and molecular life sciences 15 (1959), S. 197-198 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The concentration of histamine in plasma of rats is changed by injection of psychopharmacons as follows: decreased by narcotics (ether, chloroform) and phantastics (LSD, mescaline), increased by tranquilizers (reserpine, chlorpromazine) a hypnotic (numal) and psychotomimetics (iproniacide, amphetamine).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02158704
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  • 8
    Electronic Resource
    Electronic Resource
    Nachweis von3H-Digitoxin in der Herzmuskelzelle (1962)
    Springer
    Cellular and molecular life sciences 18 (1962), S. 35-36 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary In autoradiographs of intraventricular muscle bundles of beef heart, tritiated digitoxine is found outside the membrane and inside the muscle cell at the moment of maximal inotropic action.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02136647
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  • 9
    Electronic Resource
    Electronic Resource
    Interactions between contractile and regulatory proteins of the myofibril (1972)
    Springer
    Cellular and molecular life sciences 28 (1972), S. 891-892 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Zusammenfassung Die Regulationseiweisse (Tropomyo sin und Troponinkomplex), welche die Wechselwirkung der kontraktilen Eiweisse in der Myofibrille steuern, zeigen eine spezifische und unspezifische Bindung an den Actomyosinkomplex. Die spezifisch gebundene Menge der Regulationseiweisse beträgt nur etwa 1/100 derjenigen von Actomyosin, genügt aber trotzdem, um die Steuerung der Mg-ATPase und damit der Muskelkontraktion durch Ca2+ zu gewährleisten.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01924926
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  • 10
    Electronic Resource
    Electronic Resource
    Bestimmung der Zahl aktiver Zentren der Acetylcholinesterase in motorischen Endplatten (1965)
    Springer
    Cellular and molecular life sciences 21 (1965), S. 402-403 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary 32P or14C-labelled diisopropyl-fluoro-phosphate (DFP) was bound to endplates of mouse diaphragms by incubation. The number of molecules was determined by densitometric measurement of autoradiographs. One endplate contains 2.4·107 active centres for acetylcholine, blocked by DFP. The turnover time for acetylcholine is very short: 15µsec.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02139769
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