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  • Polymer and Materials Science  (5)
  • Renal scarring  (3)
  • Brain  (2)
  • Copper  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Preparation of an anion-exchange resin with quaternary phosphonium chloride and its adsorption behaviour for noble metal ions
    Amsterdam : Elsevier
    Analytica Chimica Acta 274 (1993), S. 293-297 
    Details
    ISSN: 0003-2670
    Keywords: Copper ; Extraction ; Gold ; Heavy metals ; Ion exchange
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0003-2670(93)80478-4
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Mono- and dinuclear alkoxide copper complexes with PPh"3 ligands
    Amsterdam : Elsevier
    Journal of Organometallic Chemistry 473 (1994), S. 359-369 
    Details
    ISSN: 0022-328X
    Keywords: Alkoxide ; Copper ; Crystal structure ; Hydrogen bonding
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0022-328X(94)80138-X
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Effect of prednisolone on ascending renal infection due to biofilm disease and lower urinary tract obstruction in rats (1995)
    Springer
    Urological research 22 (1995), S. 383-387 
    Details
    ISSN: 1434-0879
    Keywords: Lower urinary tract obstruction ; Biofilm disease ; Renal scarring ; Prednisolone ; Ciprofloxacin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A model of renal infection due to lower urinary tract obstruction and biofilm disease was constructed for the study of renal scarring by inserting glass beads coated with bacterial biofilm into the bladder of rats and then clamping the urethra. We previously reported the effect of antimicrobial therapy used in combination with the anti-inflammatory agent prednisolone to prevent renal scarring. In this study we investigated the effect of prednisolone on renal scar formation using our new model. Renal scarring could not be prevented in the group in which prednisolone was administered in the period during which the urethra was regularly being clamped. In contrast, scarring was prevented in the group that began to receive prednisolone after the period of clamping had ended. Therefore, in cases of lower urinary tract obstruction prednisolone should only be administered for the prevention of renal scarrring after the obstruction has been resolved.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00296880
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  • 4
    Electronic Resource
    Electronic Resource
    Increased renal scarring by bacteria with mannose-sensitive pili (1990)
    Springer
    Urological research 18 (1990), S. 299-303 
    Details
    ISSN: 1434-0879
    Keywords: MS pili ; Serratia marcescens ; Renal scarring
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Renal scars are thought to be the end stage of chronic pyelonephritis and one of the most important causes of renal insufficiency and renal hypertension. The role of bacterial pili was examined in scar formation after an infection of newly constructed bacterial strains using the recombinant DNA technique, which possessed either mannose resistant (MR) or mannose sensitive (MS) pili of Serratia marcescens. Strains that differed in only a single virulence factor, namely, MR or MS pili, were used in a rat model of chronic pyelonephritis. In this model, MS-piliated bacteria stimulated renal scarring more severely than non-piliated or MR-piliated bacteria.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00300774
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  • 5
    Electronic Resource
    Electronic Resource
    Role of superoxide in renal scarring following infection by mannose-sensitive piliated bacteria (1991)
    Springer
    Urological research 19 (1991), S. 229-233 
    Details
    ISSN: 1434-0879
    Keywords: Pyelonephritis ; Renal scarring ; Pathogenesis ; Serratia marcescens ; Piliation ; Superoxide dismutase ; Leukocytes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The role of superoxide in scar formation following renal infection caused by mannose-sensitive (MS) piliated strains of bacteria was studied in the experimental pyelonephritis model using female Sprague-Dawley rats. The MS piliated strain stimulated renal scarring to a significantly greater extent than either the non-piliated or MR-piliated strain. Modulation of leukocytes by administering cyclophosphamide to induce neutropenia and colchicine to inhibit leukocyte migration was effective in preventing renal scarring. Treatment with superoxide dismutase during the early stage of infection was also effective in preventing scar formation. Finally, the production of superoxide by rat leukocytes was significantly larger following stimulation by MS piliated than either the nonpiliated or MR piliated strains. These observations suggest that superoxide released from leukocytes plays a critical role in the development of renal scarring following a bacterial infection, especially by MS piliated strains.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00305300
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  • 6
    Electronic Resource
    Electronic Resource
    Characteristics of binding of [3H]NE-100, a novel sigma-receptor ligand, to guinea-pig brain membranes (1995)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 351 (1995), S. 244-251 
    Details
    ISSN: 1432-1912
    Keywords: Key words Sigma binding sites ; NE-100 ; (N ; N-dipropyl-2-[4-methoxy-3-(2-phenylethoxy) phenyl]-ethylamine monohydrochloride) ; Radiolabeled ligand binding ; Brain ; Guinea-pig
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  We examined the characteristics of binding of radiolabeled N,N-dipropyl-2-[4-methoxy-3-(2-phenyl- ethoxy)phenyl]-ethylamine monohydrochloride ([3H] NE-100), a highly potent and selective sigma-receptor ligand, to guinea-pig brain membranes. [3H]NE-100 showed saturable and reversible binding to sigma binding sites. A dissociation constant (Kd) and maximal numbers of binding sites (B max) obtained from Scatchard plot analysis were 1.2±0.1 nM and 1049.3±115.1 fmol/mg protein (n=3), respectively. NE-100 was the most potent inhibitor of [3H]NE-100 binding among several structurally dissimilar sigma-receptor ligands, including haloperidol and (+)-pentazocine. (+)-Benzomorphanes had more than a 10-fold potent inhibitory activity over (−)-benzomorphanes, with regard to [3H]NE-100 binding. The binding of [3H]NE-100 was not influenced by histaminergic, dopaminergic, adrenergic, serotonergic cholinergic or glutaminergic agents at 10-7 M. GTP-γ-S and phenytoin also did not affect the binding of [3H]NE-100. A higher [3H]NE-100 binding was observed in the cerbellum and medulla oblongata. Except for the nuclear fraction, the highest level of [3H]NE-100 binding to subcellular fractions was observed in microsomal fractions. These results suggest that NE-100 selectively binds, with a high affinity, to sigma-1 binding sites in guinea-pig brain membranes, as an “antagonist”.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00233243
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  • 7
    Electronic Resource
    Electronic Resource
    Characteristics of binding of [3H]NE-100, a novel sigma-receptor ligand, to guinea-pig brain membranes (1995)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 351 (1995), S. 244-251 
    Details
    ISSN: 1432-1912
    Keywords: Sigma binding sites ; NE-100 (N,N-dipropyl-2-[4-methoxy-3-(2-phenylethoxy) phenyl]-ethylamine monohydrochloride) Radiolabeled ligand binding ; Brain ; Guinea-pig
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We examined the characteristics of binding of radiolabeled N,N-dipropyl-2-[4-methoxy-3-(2-phenylethoxy)phenyl]-ethylamine monohydrochloride ([3H] NE-100), a highly potent and selective sigma-receptor ligand, to guinea-pig brain membranes. [3H]NE-100 showed saturable and reversible binding to sigma binding sites. A dissociation constant (Kd) and maximal numbers of binding sites (B max) obtained from Scatchard plot analysis were 1.2 ± 0.1 nM and 1049.3 ± 115.1 fmol/mg protein (n = 3), respectively. NE-100 was the most potent inhibitor of [3H]NE-100 binding among several structurally dissimilar sigma-receptor ligands, including haloperidol and ( + )-pentazocine. ( + )-Benzomorphanes had more than a 10-fold potent inhibitory activity over (−)-benzomorphanes, with regard to [3H]NE-100 binding. The binding of [3H]NE-100 was not influenced by histaminergic, dopaminergic, adrenergic, serotonergic cholinergic or glutaminergic agents at 10−7 M. GTP-γ-S and phenytoin also did not affect the binding of [3H]NE-100. A higher [3H]NE-100 binding was observed in the cerbellum and medulla oblongata. Except for the nuclear fraction, the highest level of [3H]NE-100 binding to subcellular fractions was observed in microsomal fractions. These results suggest that NE-100 selectively binds, with a high affinity, to sigma-1 binding sites in guinea-pig brain membranes, as an “antagonist”.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00233243
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  • 8
    Electronic Resource
    Electronic Resource
    Thermal conductivity of a polymer composite filled with mixtures of particles (1987)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 34 (1987), S. 1429-1437 
    Details
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: A new thermal conduction model is proposed for a polymer system filled with a mixture of several types of particles. Predicted values by the new model are compared with experimental data. The model is derived by extending a model that was previously proposed for a two-phase system. The following equation is derived from the new model: log λ = V · (X2 · C2 · log λ2 + X3 · C3 · log λ3 + (1 - V) log (C1 · λ1. When the thermal conductivities of polymer and particles (λ1, λ2, λ3, …) and a mixing ratio of particles (X2, X3, …) are known, thermal conductivity of the filled polymer (λ) with several types of particles can be estimated from the equation, with any volume content of particles (V). Furthermore, from each polymer-filler composite (two-phase system) data, the thermal conductivity of a composite filled with different filler particles can be estimated.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/app.1987.070340408
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  • 9
    Electronic Resource
    Electronic Resource
    Preparation of the polymer bearing pendant quinonoid groups by UV irradiation and its photocrosslinking (1987)
    Bognor Regis [u.a.] : Wiley-Blackwell
    Journal of Polymer Science Part A: Polymer Chemistry 25 (1987), S. 3173-3176 
    Details
    ISSN: 0887-624X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/pola.1987.080251119
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  • 10
    Electronic Resource
    Electronic Resource
    Thermal conductivity of a polymer filled with particles in the wide range from low to super-high volume content (1990)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 40 (1990), S. 929-941 
    Details
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Polyethylene and polystyrene composites filled with high-volume content of filler particles (quartz or Al2O3) were prepared by ordinary melt-casting method to effectively increase the thermal conductivity. The result, however, suggested that fractional void volume cssentially occupied by filler particles is left unfilled when high or super-high content of filler is used. After investigating the relation between the mixing ratio of different sized filler particles and the fractional voidage under various compression intensities, a mixture of filler was found to give minimum fractional voidage. Polymers filled with such an optimum mixture of fillers for minimum fractional voidage were then prepared under compression. Thus, expected monotonous increases in thermal conductivity in the wide range from low to super-high filler content were obtained. Further, it was confirmed that a predictive model proposed by us agreed quite satisfactorily with the experimental data in comparison with many other models.
    Additional Material: 11 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/app.1990.070400526
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