Library

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    ISSN: 1432-1076
    Keywords: Acatalasia ; Cerebro-hepato-renal syndrome ; Cirrhosis ; Hemochromatosis ; Cytochrome abnormalities ; Peroxisomes ; Mitochondria ; Oxidative phosphorylation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A patient with a cerebro-hepato-renal syndrome was investigated. The visceral manifestations were those of the Zellweger syndrome (ZS); however, the child exhibited muscular hypertonia and survived into the 2nd year of life. Ultramicroscopically, hepatocytes were lacking peroxisomes, but, contrary to findings in one patient with ZS [2], contained smooth endoplasmic reticulum. No catalase was found by histochemistry or spectroscopy. Mitochondria showed normal succinate and glutamate respiration, and normal coupling of respiration to the phosphorylation potential. The cytochrome (cyt) content was diminished to one-third with an abnormally inversed redox patterns of the respiratory chain in the controlled state, cyt b being 5%, cyt c 23% reduced. The oxygen affinity of cyt a 3 was normal. These findings exclude a defect in the nonheme iron protein region of the respiratory chain as described in ZS [2], but point to a functional abnormality of cyt b in our patient.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 372 (1987), S. 860-860 
    ISSN: 1435-2451
    Keywords: Dubious histopathological diagnosis ; Extent of surgery ; Prognosis ; Zweifelhafte Dignität ; Radikaloperation ; Prognose
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Das Hämangiopericytom ist ein sehr seltener Gefässtumor, der von den Pericyten ausgeht und deshalb im gesamten Organismus auftreten kann. Pathohistologisch ist eine sichere Aussage über die Dignität nicht möglich. Mindestens 50% der Patienten haben einen malignen Verlauf. Bei 12 Patienten in unserer Klinik mit histologisch malignem Hämangiopericytom hatten nur diejenigen eine Überlebenszeit von mehr als 2 Jahren, bei denen der Tumor radikal im Gesunden entfernt werden konnte. Wir folgern aus unseren Erfahrungen, dass dieser Tumor immer als potentiell maligne angesehen und dementsprechend operiert werden muss.
    Notes: Summary The haemangiopericytoma is a very rare vascular tumor, which is produced by the pericytes and can therefore arise anywhere in the entire organism. It is impossible to assess the malignancy with histopathological methods. At least 50% of the patients suffer a malignant growth in the followup. Of 12 patients with a histologically malignant haemangiopericytoma, only those whose tumor could be resected radically survived more than 2 years. We conclude from our experience that this kind of tumor should always be regarded as malignant and should be treated accordingly.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...