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  • Engineering  (12)
  • Chemical Engineering  (6)
  • Morphometry  (3)
  • Cytogenetics  (2)
  • IQ  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Maximal oxygen consumption and pulmonary diffusing capacity: A direct comparison of physiologic and morphometric measurements in canids
    Amsterdam : Elsevier
    Respiration Physiology 54 (1983), S. 173-188 
    Details
    ISSN: 0034-5687
    Keywords: Carbon monoxide ; Cayote ; Conductance ; Dog ; Fox ; Lung ; Morphometry ; Oxygen ; Pulmonary diffusing capacity ; Wolf
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0034-5687(83)90055-5
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Contribution of immunophenotypic and genotypic analyses to the diagnosis of acute leukemia (1995)
    Springer
    Annals of hematology 71 (1995), S. 13-27 
    Details
    ISSN: 1432-0584
    Keywords: Acute leukemia ; Diagnosis ; Immunophenotypic ; Cytogenetics ; Molecular genetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Diagnostic accuracy in acute leukemia (AL) can be improved if traditional morphology and cytochemistry are supplemented with immunophenotypic and genotypic analyses. This multiparameter approach is of crucial importance for the management of patients, as it enables the identification of leukemic syndromes with distinct biological features and response to treatment. Immunophenotyping using monoclonal antibodies has been universally accepted as a useful adjunct to morphological criteria. This technique is particularly valuable in diagnosing and subclassifying acute lymphoblastic leukemia and is also essential in certain types of acute myeloid leukemia (AML), such as AML with minimal differentiation or acute megakaryoblastic leukemia. Cytogenetic findings can be quite helpful in establishing the correct diagnosis and can add information of prognostic significance. A number of specific chromosomal abnormalities have been recognized that are very closely, and sometimes uniquely, associated with morphologically and clinically distinct subsets of leukemia. An even more basic understanding of normal and malignant hematopoietic cells has begun to evolve as molecular biology begins to unravel gene misprogramming by Southern and Northern blot analysis, the polymerase chain reaction, and fluorescence in situ hybridization. With the extensive use of these techniques it has become apparent that a proportion of leukemias exhibit the biologically relevant molecular defect in the absence of a karyotypic equivalent. On the other hand, apparently uniform chromosomal abnormalities such as the t(1;19) (q23;p13), t(9;22) (q33;q11), t(8;14) (q24;q32), or t(15;17) (q21;q21) may differ at the molecular level. Data collected from these modern technologies have introduced a greater complexity, which needs to be taken into consideration to improve both the diagnostic precision and the reproducibility of current classifications.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01696228
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Contribution of immunophenotypic and genotypic analyses to the diagnosis of acute leukemia (1995)
    Springer
    Annals of hematology 71 (1995), S. 13-27 
    Details
    ISSN: 1432-0584
    Keywords: Key words Acute leukemia ; Diagnosis ; Immunophenotypic ; Cytogenetics ; Molecular genetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  Diagnostic accuracy in acute leukemia (AL) can be improved if traditional morphology and cytochemistry are supplemented with immunophenotypic and genotypic analyses. This multiparameter approach is of crucial importance for the management of patients, as it enables the identification of leukemic syndromes with distinct biological features and response to treatment. Immunophenotyping using monoclonal antibodies has been universally accepted as a useful adjunct to morphological criteria. This technique is particularly valuable in diagnosing and subclassifying acute lymphoblastic leukemia and is also essential in certain types of acute myeloid leukemia (AML), such as AML with minimal differentiation or acute megakaryoblastic leukemia. Cytogenetic findings can be quite helpful in establishing the correct diagnosis and can add information of prognostic significance. A number of specific chromosomal abnormalities have been recognized that are very closely, and sometimes uniquely, associated with morphologically and clinically distinct subsets of leukemia. An even more basic understanding of normal and malignant hematopoietic cells has begun to evolve as molecular biology begins to unravel gene misprogramming by Southern and Northern blot analysis, the polymerase chain reaction, and fluorescence in situ hybridization. With the extensive use of these techniques it has become apparent that a proportion of leukemias exhibit the biologically relevant molecular defect in the absence of a karyotypic equivalent. On the other hand, apparently uniform chromosomal abnormalities such as the t(1;19) (q23;p13), t(9;22) (q33;q11), t(8;14) (q24;q32), or t(15;17) (q21;q21) may differ at the molecular level. Data collected from these modern technologies have introduced a greater complexity, which needs to be taken into consideration to improve both the diagnostic precision and the reproducibility of current classifications.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01696228
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Comparison of differentiation patterns in 12-O-tetradecanoylphorbol-13-acetate-treated epidermis and fetal epidermis (1985)
    Springer
    Archives of dermatological research 277 (1985), S. 457-465 
    Details
    ISSN: 1432-069X
    Keywords: Epidermis ; Hyperplasia ; TPA ; Stereology ; Morphometry ; Tumor promotors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary 12-O-Tetradecanoylphorbol-13-acetate (TPA)-treated adult epidermis as well as untreated fetal and adult epidermis were investigated to elucidate the effect of TPA in terms of cell differentiation using techniques of ultrastructural stereology. Twenty-four hours after a single application of TPA, the treated epidermis was characterized by involutional changes, i. e., increased volume density of intercellular spaces and of mitochondria, vacuoles, and cytoplasmic ground substance in the basal layer. However, 48 h after application, the TPA-treated epidermis was very similar to fetal epidermis, i. e., high volume density of nuclei ribosomes, rough endoplasmic reticulum, membrane-coating granules, and keratohyalin granules, and low volume density of bundled filaments in the upper layers. These stereological data indicate that the changes observed 48 h after TPA treatment were related not only to increased cell proliferation but also to inhibition of cell differentiation expressed as a reversion of the adult differentiation patterns and the acquisition of fetal characteristics in all epidermal layers.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00510063
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Estimating transit time for capillary blood in selected muscles of exercising animals (1992)
    Springer
    Pflügers Archiv 421 (1992), S. 578-584 
    Details
    ISSN: 1432-2013
    Keywords: Muscle ; Morphometry ; Blood flow ; Microcirculation ; Oxidative capacity ; Oxygen transport ; V2,max
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The mean minimal capillary transit time was estimated in muscles of various animals using a combination of physiological and morphometric methods. Radioactive microspheres were injected intravascularly in various animals running on a treadmill at maximum oxygen consumption rate (VO2,max) to label blood flow to individual muscles. The muscles were then removed and preserved by standard methods for electron microscopy. The volume density of mitochondria was measured to assess muscle oxidative capacity. Capillary densities in muscle cross-sections, capillary diameters and tortuosities were incorporated into an estimate of capillary volume per unit muscle mass. Mean capillary transit time (t c) in the exercising muscles was estimated by dividing mass-specific capillary volume by mass-specific blood flow. Estimates of t c ranged from values near 1 s in horse heart and thigh muscles to 0.2 s in duck gastrocnemius. The relationship between muscle blood flow and t c was hyperbolic. The experimental data indicate a limiting value of 0.2 s for transit times at very high blood flows. There was no correlation between t c and body-mass-specific VO2,max.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00375054
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  • 6
    Electronic Resource
    Electronic Resource
    The association between phenylthiocarbamide (PTC) tasting ability and psychometric variables (1983)
    Springer
    Behavior genetics 13 (1983), S. 191-196 
    Details
    ISSN: 1573-3297
    Keywords: personality ; IQ ; phenylthiocarbamide (PTC)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Psychology
    Notes: Abstract Tasters and nontasters of the chemical phenylthiocarbamide differ in personality and in IQ test scores. Using an undergraduate sample, nontasters were significantly more “placid” (rather than “apprehensive”) “relaxed” (rather than “tense”), and “practical” (rather than “imaginative”) and scored higher on the more visuospatial component of an IQ test than their taster counterparts.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01065667
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    Assortative mating for IQ and personality due to propinquity and personal preference (1988)
    Springer
    Behavior genetics 18 (1988), S. 339-345 
    Details
    ISSN: 1573-3297
    Keywords: assortative mating ; IQ ; Eysenck's Personality Inventory (EPI) ; extraversion ; neuroticism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Psychology
    Notes: Abstract The role of personal preference as an active process in mate selection is contrasted with the more passive results of limitations of available mates due to social, educational, and geographical propinquity. The role of personal preference estimated after removing the effects of variables representing propinquity was still significant for IQ and Eysenck's extraversion-introversion and inconsistency (lie) scales, even though small.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01260934
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  • 8
    Electronic Resource
    Electronic Resource
    Experimental and numerical investigations of the vacuum-forming process (1992)
    Stamford, Conn. [u.a.] : Wiley-Blackwell
    Polymer Engineering and Science 32 (1992), S. 1163-1173 
    Details
    ISSN: 0032-3888
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: This paper exmines the influence of process variables on final thickness distributions for vacuum-formed thermoplastic parts. The process variables investigated include evacuation rate, sheet surface temperature, mold temperature, and material slip over the mold surface. The experimental data presented include, in addition to thicknesses, sheet surface temperature obtained via infrared thermography. A finite element program to model the vacuum-forming process is discussed, and the wall thickness distribution predicted by this program for a vacuum-formed part is compared with the results of the experiments.
    Additional Material: 16 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/pen.760321613
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    Paper (German National Licenses)
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  • 9
    Electronic Resource
    Electronic Resource
    On the construction and numerical solution of transmission-line and lumped network models of Maxwell's equations (1980)
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 15 (1980), S. 13-30 
    Details
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: It is sometimes convenient to express a numerical algorithm in terms of a network model. The physical picture given can often help the engineer to visualize the properties of the method. In field problems, a lumped network model corresponds to a space discrete field while a transmission-line model corresponds to a field which is discrete in space and time. In this paper, the relationship is given between the lumped network models and transmission-line network models used in the steady-state solution of Maxwell's equations in two and three space dimensions. The use of dual networks is also discussed. An analysis is given for the velocity of waves travelling in any direction across the networks and this is used to compare the accuracy of the models. The use of diakoptics or substructures for the solution of large networks is outlined and this is illustrated by a compound two-dimensional example.
    Additional Material: 10 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/nme.1620150103
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  • 10
    Electronic Resource
    Electronic Resource
    Thermomechanical properties of 1C molding compoundsPresented at the Annual Meeting of American Institute of Chemical Engineers in San Francisco, California on November 6, 1989. (1990)
    Stamford, Conn. [u.a.] : Wiley-Blackwell
    Polymer Engineering and Science 30 (1990), S. 609-617 
    Details
    ISSN: 0032-3888
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Eight commercial semiconductor grade epoxy compounds that are used to encapsulate 1C (integrated circuit) devices have been evaluated for their ability to minimize the development of thermal stresses which can cause failure during device temperature cycling. Thermal expansion, dynamic modulus and adhesion studies are used to describe the mechanical interaction between the plastic package and the silicon device it surrounds. A “figure of merit” is defined for the development of stress on the 1C device as it is cooled after the packaging process. The stress is shown to be proportional to the product of three terms: (αp-αs) Ep (Tanch-T) where αp and αs are the expansion coefficients for the plastic and silicon, respectively, Ep is the modulus of the epoxy and Tanch is the temperature at which the epoxy becomes anchored to the silicon device during transfer molding. In addition, the importance of good adhesion between the epoxy encapsulant and the silicon device to prevent package cracking has been demonstrated by finite element analysis and a novel adhesion test.
    Additional Material: 16 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/pen.760301008
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