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  • Chemistry  (12)
  • Major depressive disorder  (2)
  • Na+/H+ antiport  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Electroencephalogram and neuroendocrine parameters in pubertal and adolescent depressed children
    Amsterdam : Elsevier
    Journal of Affective Disorders 6 (1984), S. 265-272 
    Details
    ISSN: 0165-0327
    Keywords: Adolescence ; DST ; GH stimulation ; Major depressive disorder ; Puberty ; REM latency
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine , Psychology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/S0165-0327(84)80004-X
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  • 2
    Electronic Resource
    Electronic Resource
    Electroencephalogram and neuroendocrine parameters in pubertal and adolescent depressed children
    Amsterdam : Elsevier
    Journal of Affective Disorders 6 (1984), S. 265-272 
    Details
    ISSN: 0165-0327
    Keywords: Adolescence ; DST ; GH stimulation ; Major depressive disorder ; Puberty ; REM latency
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine , Psychology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/S0165-0327(84)80004-X
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Platelet Na+/H+ antiport activity in patients with insulin-dependent diabetes mellitus with and without diabetic nephropathy (1993)
    Springer
    Journal of molecular medicine 71 (1993), S. 119-125 
    Details
    ISSN: 1432-1440
    Keywords: Na+/H+ antiport ; Hypertension ; Diabetic nephropathy ; Hereditary factors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The incidence of diabetic nephropathy in patients with insulin-dependent diabetes mellitus (IDDM) may depend on factors other than the quality of diabetes control. Hypertension is an additional factor associated with a high degree of renal involvement in IDDM. One abnormality consistantly observed in various tissues of patients with essential hypertension is enhanced activity of the Na+/H+ antiport. In the present study we have therefore studied platelet antiport activity in 41 healthy subjects (control), in 22 patients with untreated essential hypertension (EH), and in 35 normotensive IDDM patients (type 1). Of these patients 17 exhibited signs of diabetic nephropathy (group 1) while 18 had no evidence for renal involvement of IDDM in spite of a duration of IDDM of at least 10 years (group 2). The two IDDM patient groups were undistinguishable with respect to age, body mass index, and arterial blood pressure (group 1, 117.9±2.4/78.4±1.5 mmHg; group 2, 113.9±3.6/76.1±1.8 mmHg). Antiporter activity was determined from the rate of cell volume changes induced by propionic acid. Platelet Na+/H+ exchange activity averaged 23.43±0.43 10−3·s−1 in control subjects and was markedly elevated in EH (28.38±0.62 10−3·s−1 P〈0.01). Antiport activity in group 2 patients without nephropathy averaged 24.54±0.57 10−3·s−1 and was undistinguishable from the control group. However, platelet Na+/H+ antiport activity was significantly stimulated in group 1 patients with nephropathy as compared to group 2(26.95±0.73 10−3. s−1 ; P〈0.025). Our results show that renal involvement in IDDM is associated with enhanced activity of the platelet Na+/H+ antiport.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00179992
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  • 4
    Electronic Resource
    Electronic Resource
    Hypertonic saline infusion induces activation of the lymphocyte Na+/H+ antiport and cytosolic alkalinization in healthy human subjects (1994)
    Springer
    Journal of molecular medicine 72 (1994), S. 817-821 
    Details
    ISSN: 1432-1440
    Keywords: Cell volume regulation ; Hypertonicity ; Lymphocytes ; Na+/H+ antiport ; Saline infusion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The Na+/H+ antiport is a membrane transport protein that extrudes intracellular protons in exchange for extracellular sodium. Some details of its physiological and pathophysiological role remain poorly defined. Experimental evidence suggests that the antiporter is involved in the regulation of cell volume. In the present study, we therefore investigated the activity of the lymphocyte Na+/H+ antiport in nine healthy volunteers following acute hypertonic (2.5%) saline infusion (4 mmol NaCl/kg over 120 min). Antiport activity was measured after acidifying the cells with Na+ propionate (5–40 mM) using the fluorescent dye bis-carboxyethyl carboxyfluorescein. Hypertonic saline induced significant increases in plasma osmolality (308.4±2.3 vs. 293.5±2.7 mOsm/kg; P〈0.01), serum Na+ (150.8±3.7 vs. 138.9±0.5 mmol/kg; P〈0.01), and Cl− concentrations (118.0±3.9 vs. 101.1±1.0 mmol/kg; P〈0.01). Extracellular hypertonicity was followed by a stimulated activity of the lymphocyte Na+/H+ antiport with an increase in the apparent V max values from 2.44±0.16 to 3.27±0.34 10−3 s−1 (P〈0.01) and a slight rise in pK from 6.81±0.03 to 6.87±0.03 (P〈0.05) after hypertonic saline. In addition to antiport activation, cytosolic alkalinization was observed with cytosolic pH values averaging 6.90±0.02 before and 6.99±0.02 (P〈0.01) after hypertonic saline. Our results show for the first time that acute extracellular hypertonicity in man due to hypertonic NaCl loading is associated with a stimulated lymphocyte Na+/H+ antiport activity and cytosolic alkalinization.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00190734
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  • 5
    Electronic Resource
    Electronic Resource
    Zum Einfluß von Polyvinylsulfat auf die Photodimerisierung von AcridiziniumperchloratHerrn Professor Dr. Dr. H. G. O. Becker zum 70. Geburtstag gewidmet (1992)
    New York, NY : Wiley-Blackwell
    Journal für Praktische Chemie/Chemiker-Zeitung 334 (1992), S. 509-514 
    Details
    ISSN: 0941-1216
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The Influence of Sodium Polyvinylsulfate on the Photodimerization of Acridizinium PerchlorateDuring the irradiation of aqueous solutions of acridizinium perchlorate (λexc = 405 nm) a photodimer of this compound is formed. The quantum yield of the reaction depends on the concentration of the acridizinium ion. In 10-4 m solutions the quantum yield of dimerization is π = 0.0054 ± 0.0005. Addition of the anionic polyelectrolyte sodium polyvinylsulfate leads to a considerable increase of the quantum yield (up to π = 0.6) in dependence on the concentration of the polyion. A kinetic model is developed, including the electrostatic interaction of the acridizinium cation and the polyanion.The influence of diazonium cations as competitive agent is investigated and dicussed.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/prac.19923340611
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  • 6
    Electronic Resource
    Electronic Resource
    Die Bedeutung von Rostschichten für den Ablauf von Korrosionsreaktionen bei niedrig legierten StählenHerrn Professor Dr. Wilhelm Schwenk zum 60. Geburtstag gewidmet (1991)
    Weinheim [u.a.] : Wiley-Blackwell
    Materials and Corrosion/Werkstoffe und Korrosion 42 (1991), S. 467-472 
    Details
    ISSN: 0947-5117
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Influence of rust layers on corrosion reactions of low alloy steelsRust layers formed on iron base alloys are electrochemically highly reactive. Due to a polarisation of these oxide scales solid state reactions are induced, by which the 3-valent iron oxides are reduced. These redox reactions allow the dissolution of iron without the reduction of oxygen and therefore increase the corrosion rate, if the corrosion conditions vary periodically or if the material is coated by a polymer layer. Due to the oxide reduction electron-conducting oxides are formed, which determine the rate of the oxygen reduction. This causes the loss of adhesion for polymer coated and oxide covered iron substrates.
    Notes: Die auf Fe-Basislegierungen gebildeten Rostschichten sind elektronisch sehr reaktiv. Durch Polarisation dieser Oxidschichten werden Festkörperreaktionen ermöglicht, die zur Reduktion der 3-wertigen Oxidhydrate führen. Diese Redox-Reaktionen erlauben eine Eisenauflösung ohne Reduktion von Sauerstoff und erhöhen damit den Metallabtrag insbesonders bei periodisch variierenden Korrosionsbedingungen und bei polymerbeschichteten Werkstoffoberflächen. Durch die Oxidreduktion werden elektronenleitende Oxide gebildet, die die Kinetik von Sauerstoffreduktion bestimmen. Schließlich ändert sich bei der Reduktion der Rostschicht die Rostmorphologie. Dies führt zu einem Haftungsverlust bei polymerbeschichteten oxidbelegten Metalloberflächen.
    Additional Material: 10 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/maco.19910420905
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  • 7
    Electronic Resource
    Electronic Resource
    Zur Kenntnis des Calciumcarbides. I. Über eine neue kristallisierte Phase des Calciumcarbides (1937)
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 232 (1937), S. 61-74 
    Details
    ISSN: 0863-1786
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: 1. Calciumcarbid, welches gewöhnlich bei seiner technischen Gewinnung in flächenzentriert-tetragonalar Struktur (a = 5,48, c = 6,37 Å) (I) erhalten wird, bildet in Gegenwart von calciumeyanamid, seinem technisch wichtigsten Reaktionsprodukt, eine zweite, niedriger symmetrische Kristallart (II), welche bis etwa 15 Mol-% Cyanamid aufzunehmen vermag.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/zaac.19372320107
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  • 8
    Electronic Resource
    Electronic Resource
    Über Eigenschaften und Reaktivität von Aluminiumtrichlorid · Ethanthiol und Galliumtrichlorid · Ethanthiol (1988)
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 558 (1988), S. 160-170 
    Details
    ISSN: 0044-2313
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: On Some Properties and the Reactivity of Trichloroaluminium · Ethanthiol and Trichlorogallium · Ethanthiol ComplexesThe synthesis of aluminiumtrichloride · ethanthiol as well as galliumtrichloride · ethanthiol is given. The reactions of these 1:1-adducts with the Lewis bases N(CH3)3. P(CH3)3, O(C2H5)2 and S(CH3)2 and with the compounds (CH3)3SiSCH3 and Pb(SCH3)2 are discussed, the reaction products are investigated. Spectra as well as some chemical and physical properties of the starting material and the products are reported.
    Notes: Die Darstellung von Aluminiumtrichlorid · Ethanthiol bzw. Galliumtrichlorid · Ethanthiol wird beschrieben. Die Umsetzungen dieser 1:1-Addukte mit den Lewis-Basen N(CH3)3, P(CH3)3, O(C2H5)2 und S(CH3)2 sowie den Verbindungen (CH3)3SiSCH3 und Pb(SCH3)2 werden diskutiert, die Reaktionsprodukte werden untersucht. Spektroskopische Daten und einige chemische und physikalische Eigenschaften der Ausgangs- und Endprodukte werden mitgeteilt.
    Additional Material: 3 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/zaac.19885580116
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  • 9
    Electronic Resource
    Electronic Resource
    Beiträge zur Untersuchung anorganischer nichtstöchiometrischer Verbindungen. XLIII. Darstellung und elektronenmikroskopische Untersuchung von (Cr, Nb)12O29 (1994)
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 620 (1994), S. 839-846 
    Details
    ISSN: 0044-2313
    Keywords: Chromium niobate ; chemical transport reactions ; block structure ; high resolution electron microscopy ; Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Contributions to the Investigation of Inorganic Non-Stoichiometric Compounds. XLIII. Preparation and Electron Microscopic Investigation of (Cr, Nb)12O29Transport experiments in the system Cr/Nb/O yielded the compound (Cr, Nb)12O29 as crystalline green needles. The lattice parameters of the monoclinic cell are a = 31.162(8) Å, b = 3.8324(6) Å, c = 20.579(6) Å, β = 113.22(3)°. (Cr, Nb)12O29 is isotypic with monoclinic Nb12O29 as shown by Guinier diagrams and high resolution transmission electron microscopy. Characteristic structural building elements are [3 × 4]-blocks which are columnar sections from the ReO3 structure. In the real structure one finds numerous defects. Under the influence of the electron beam we observed reversible changes of contrast which indicates that the positions of the M-particles (M = Cr, Nb) have shifted.
    Notes: Grüne, nadelförmige Kristalle von monoklinem (Cr, Nb)12O29 entstanden bei Transportexperimenten im System Cr/Nb/O. Die Gitterparameter a = 31,162(8) Å, b = 3,8324(6) Å, c = 20,579(6) Å, β = 113,22(3)° aus Guinieraufnahmen zeigen ebenso wie Strukturabbildungen mit der hochauflösenden Durchstrahlungselektronenmikroskopie Isotypie zu monoklinem Nb12O29. Auf den Aufnahmen erkennt man als charakteristisches Bauelement [3 × 4]-Blöcke, säulenförmige Ausschnitte aus der ReO3-Struktur, sowie zahlreiche Baufehler. Reversible Veränderungen des Kontrastes unter der Einwirkung des Elektronenstrahls lassen auf Änderungen der M-Positionen (M = Cr, Nb) schließen.
    Additional Material: 11 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/zaac.19946200515
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  • 10
    Electronic Resource
    Electronic Resource
    Zum nukleophilen Abbau von Tris(pentasulfido)platinat(IV), [Pt(S5)3]2-, und Bis(pentasulfido)platinat(II),[Pt(S5)2]2- (1979)
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 452 (1979), S. 112-122 
    Details
    ISSN: 0044-2313
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: On the Nucleophilic Degradation of Tris(pentasulfido)platinum(IV), [Pt(S5)3]2-, and Bis(pentasulfido)platinum(II), [Pt(S5)2]2-The behaviour of [Pt(S5)3]2-, (I), towards sulfite, arsenite, sulfide, hydroxide, and triphenylphosphine has been studied qualitatively and quantitatively. With stoichiometric amounts of nucleophile one ring is degraded; the reaction product [Pt(S5)2]2-, (II), can be isolated. With excess of nucleophile all sulfur atoms are taken off from the platinum; with triphenylphosphine, however, (PPh3)2PtS4, (III), is formed. A mechanistic interpretation of the course of the reaction is given and supported by kinetic studies.
    Notes: Das Verhalten von [Pt(S5)3]2-, (I), gegenüber Sulfit, Arsenit, Sulfid, Hydroxid und Triphenylphosphin wird qualitativ und quantitativ untersucht. Mit stöchiometrischen Mengen an Nukleophil wird ein Ring abgebaut; als Reaktionsprodukt kann [Pt(S5)2]2-, (II), isoliert werden. Mit Überschuß an Nukleophil werden alle Schwefelatome vom Platin abgelöst; mit Triphenylphosphin entsteht dagegen (PPh3)2PtS4, (III). Der Reaktionsablauf wird mechanistisch gedeutet und durch kinetische Untersuchungen erhärtet.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/zaac.19794520116
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