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  • 1
    ISSN: 0942-0940
    Keywords: Matrix metalloproteinase-9 ; pituitary adenomas ; cavernous sinus invasion ; cell immunoblot
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Twenty-two pituitary adenomas were examined on the secretion of matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of metalloproteinase-1 (TIMP-1) using a cell immunoblot assay, and discussed regarding an association between cavernous sinus invasion and the secretion of these proteins. The cell immunoblot assay, a kind of immunoblot procedure, is able to detect proteins at the single cell level and to detect the incidence of tumour cells secreting the target proteins in the total tumour cell population. The incidence of tumour cells secreting MMP-9 was significantly higher in invasive adenomas than in noninvasive ones. On the other hand, TIMP-1 secretion was not detected in any adenomas in this study. This result suggested that MMP-9 secretion, and especially the number of MMP-9-secreting cells, may be associated with cavernous sinus invasion of pituitary adenomas.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 0730-6679
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Co-rotating twin screw extruders are extensively used in polymer compounding. In co-rotating twin screw extruders, the kneading disk region is the most influential for compounding efficiency. However, only a few studies have so far been made for the flow analysis of the kneading disk region. This may be due to the fact that phenomena relating to kneading are overly complicated. In this study, the flow in the kneading disk region was investigated using a closed-type co-rotating twin screw single-staged mixer. We measured torque, pressure, and resin temperature under various compounding conditions of polypropylene. It was found that the flow characteristics obtained were identical with those measured using a capillary rehometer. © 1996 John Wiley & Sons, Inc.
    Additional Material: 13 Ill.
    Type of Medium: Electronic Resource
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