Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Karzinome in vorbestehenden Warthin-Tumoren (Zystadenolymphomen) der Parotis Klassifikation, Pathogenese und Differentialdiagnose (1997)
    Springer
    Der Pathologe 18 (1997), S. 359-367 
    Details
    ISSN: 1432-1963
    Keywords: Schlüsselwörter Warthin-Tumor ; Karzinom ; Pathogenese ; Klassifikation ; Differentialdiagnose ; Key words Warthin tumour ; Carcinoma ; Pathogenesis ; Classification ; Differential diagnosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Malignant transformation of pre-existing Warthin tumours of the parotid gland in carcinomas is very rare compared with the development of carcinomas in pre-existing pleomorphic adenomas. Five cases examined in the Salivary Gland Register of Hamburg 1965–1996 were classified in 2 cases as mucoepidermoid carcinoma and in each of one case as oncocytic carcinoma, squamous cell carcinoma and acinic cell carcinoma. In the pathogenesis the benign oncocytic epithelial formations at the surface of the cystic spaces are restricted by malignant neoplastic epithelial cells in the course of which transitions of squamous cell metaplasia or goblet cell metaplasia can be observed. In the further course an infiltrating spread of the carcinoma takes place into the lymphoid stromal component of the Warthin tumour, sometimes also an infiltration of the surrounding tissue und rarely to cervical lymph node metastases. The own findings are analysed concerning the classification of the carcinomas and the differential diagnosis under consideration of the until now reported cases of the literature.
    Notes: Zusammenfassung Eine maligne Transformation vorbestehender Warthin-Tumoren der Parotis in Karzinome ist – verglichen mit der Entwicklung von Karzinomen in vorbestehenden pleomorphen Adenomen – sehr selten. In 5 Fällen, welche von 1965 bis 1996 im Speicheldrüsen-Register Hamburg beobachtet wurden, handelte es sich um 2 Mukoepidermoidkarzinome und um je 1 onkozytäres Karzinom, Plattenepithelkarzinom und Azinuszellkarzinom. In der Pathogenese werden die benignen onkozytären Epithelverbände durch maligne neoplastische Epithelformationen zunächst an der Oberfläche der Tumorzysten des Warthin-Tumors ersetzt, wobei sich auch Übergänge von Plattenepithel- und Becherzellmetaplasien zu malignen Zellformen beobachten lassen. Im weiteren Verlauf kommt es zu einer infiltrativen Ausbreitung des Karzinoms in das lymphoide Stroma des Warthin-Tumors, mitunter auch zur Infiltration des angrenzenden Gewebes und seltener zu Lymphknotenmetastasen. Die eigenen Befunde werden im Hinblick auf die Klassifikation der Karzinome und die Differentialdiagnose mit den bisher im Schrifttum mitgeteilten Beobachtungen analysiert.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002920050227
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Über das Vorkommen sog. heller Zellen in Speicheldrüsentumoren (1978)
    Springer
    Journal of cancer research and clinical oncology 91 (1978), S. 165-182 
    Details
    ISSN: 1432-1335
    Keywords: Clear cells ; Salivary gland tumors ; Ultrastructure ; Differential diagnosis ; Helle Zellen ; Speicheldrüsentumoren ; Ultrastruktur ; Differentialdiagnose
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Zu den hellzelligen Speicheldrüsentumoren gehören monomorphe hellzellige Adenome, hellzellige Carcinome, hellzellige Varianten der Acinus- und Mucoepidermoidtumoren, Talgdrüsentumoren, Speichelgang-Carcinome und pleomorphe Adenome mit hellzelligen Abschnitten. Der lichtmikroskopische, deskriptive Begriff der hellen Zelle umfaßt bei einer weiteren cytochemischen und elektronenmikroskopischen Analyse Zellformen unterschiedlicher Herkunft und funktioneller Bedeutung. Folgende Zelltypen wurden näher analysiert: indifferente Gangzellen (geringe Organellenausbildung, Desmosomen), speichernde Streifenstückzellen (Glykogengranula, zahlreiche Mitochondrien, basales Labyrinth), Myoepithelzellen (Myofilamente, Pinocytose-Vesicel, Lipofuscingranula, Hemidesmosomen), epidermoide Zellen (Tonofilamente, Desmosomen), Becherzellen (Schleimvacuolen, basales endoplasmatisches Reticulum), Talgdrüsenzellen (Lipidtropfen, Mikrovilli, Desmosomen) und helle Acinuszellen (elektronenoptisch helle Sekretgranula, kleine Mitochondrien, kleiner Golgiapparat). In die Differentialdiagnose müssen auch hellzellige Tumorformen der Speicheldrüsenregion einbezogen werden, welche primär nicht vom Speicheldrüsengewebe ausgehen. Hierzu gehören Metastasen hypernephroider Nieren-Carcinome, Paragangliome, Glomustumoren Masson, Granularzelltumoren und alveoläre Weichteilsarkome.
    Notes: Summary Clear cell tumors of the salivary glands are monomorphic clear cell adenomas, clear cell carcinomas, clear cell variants of acinic cell and mucoepidermoid tumours, sebaceous cell tumors, salivary duct carcinomas and pleomorphic adenomas with clear cell sectors. At the light microscopical level the descriptive term of the clear cell comprises cell types of different origin and functional importance which can be differentiated by cytochemistry and electron microscopy. The following cell types were analysed precisely: indifferent duct cells (small formation of organelles, desmosomes), storing striated duct cells (glycogen granules, multiple mitochondrias, basal labyrinth), myoepithelial cells (myofilaments, pinocytosis vesicles, lipofuscin granules, hemidesmosomes), goblet cells (mucous vacuoles, basal endoplasmatic reticulum), sebaceous cells (lipid droplets, microvilli, desmosomes) and clear acinic cells (electron pale secretory granules, small mitochondrias, small golgi apparatus). Clear cell tumor types of the salivary gland region which primarely do not derive from the salivary gland tissue must also be included in the differential diagnoses. These are metastases of hypernephroid renal carcinomas, paragangliomas, glomus tumors of Masson, granular cell tumor and alveolar soft-part sarcomas.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00284023
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Das monomorphe Speichelgangadenom (1979)
    Springer
    Virchows Archiv 383 (1979), S. 77-99 
    Details
    ISSN: 1432-2307
    Keywords: Salivary duct adenoma ; Monomorphic salivary gland adenoma ; Classification ; Differential diagnosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The WHO classification of salivary gland tumours distinguishes three types of monomorphic adenomas (cystadenolymphoma, onkocytoma and ‘other types’). In the material of the salivary gland register (1965–1978), 362 monomorphic adenomas were investigated (252 cystadenolymphomas, 5 onkocytomas and 105 cases of ‘other types’). In the tumour group of ‘other types’ the ‘salivary duct adenoma’ represented the most frequent type (79 of 105 cases=75%). The following determinations were made for the definition and differential diagnosis of the salivary duct adenoma: 1. The salivary duct adenoma was localized predominantly in the parotid gland (57 cases=72%), in the other cases (22 cases=28%) in the minor salivary glands (especially upper lip, cheek and palate). The age peak is in the seventh decade, the female sex predominates with 65%. 2. In the histologic architecture trabecular, tubular and cystic duct formations can be distinguished which are limited by a PAS-positive basement membranelike substance at the outside. There is no mucoid or chondroid stroma such as is found in pleomorphic adenomas. 3. The cytologic structure is characterized by basal reserve cells (basal cells) at the outside and by variably differentiated duct epithelias at the inner side with secret production into the duct lumen. Within the trabecular lumenless formations so-called transformation cells are found. 4. The histologic and cytologic differentiation is comparable with the embryonal stages of the salivary duct system as well as with mature parts of salivary ducts. Tubular and cystic structures represent higher stages of maturation and are found more frequently than trabecular formations which correspond to the early stages of the salivary duct's embryogenesis. 5. The term ‘salivary duct adenoma’ comprises all monomorphic adenomas with ductlike structures and replaces the many synonyms previously used (‘trabecular, tubular, canalicular adenomas; cystadenomas’). Rare types of adenoma which were especially described in the minor salivary glands (‘papillary cystadenoma; sialadenoma papilliferum, intraductal papilloma’) are also included under the term ‘salivary duct adenoma’. 6. The basal cell adenoma is subclassified as a special variant of the salivary duct adenoma. The term ‘basal cell adenoma’ is only used for adenomas which possess the characteristic structure of basal cells and have a distinctly limited stroma. We found 19 basal cell adenomas (=18%) in the group of monomorphic adenomas of ‘other types’. 7. In differential diagnosis, the salivary duct adenoma must be distinguished from the stroma-poor pleomorphic adenoma and from other rare monomorphic adenomas (sebaceous lymphadenoma, clear-cell adenoma, mucous-producing adenoma, etc.).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00427012
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Die Ultrastruktur des Gabeschen Organs von Schizophyllum sabulosum L. (Diplopoda, Iuliformia) (1972)
    Springer
    Cell & tissue research 132 (1972), S. 273-285 
    Details
    ISSN: 1432-0878
    Keywords: Diplopoda ; Organ of Gabe ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Description / Table of Contents: Zusammenfassung 1. Das Gabesche Organ von Schizophyllum sabulosum ist paarig und liegt im seitlichen Clypeolabrum. Es wird von Axonen des Nervus labri medialis erreicht, der vorher Seitenzweige abgegeben hat. 2. Die Axone gehören neurosekretorischen Zellen des Protocerebrum an und enthalten Neurosekret. Die Elementargranula sind recht gleichmäßig ellipsoid, der große Durchmesser beträgt ca. 1200 Å. Die Axone enden im Organ und stellen dessen extrinsische Komponente dar. 3. Außerdem gibt es zwei intrinsische Zelltypen: 1) Drüsenparenchymzellen mit axonartigen Fortsätzen und 2) gliaartige Zellen. Die Parenchymzellen bilden Sekret in Form opaker Vakuolen, die deutlich größer als die Neurosekretgranula sind. Auffällig ist das überwiegend vesikuläre endoplasmatische Reticulum. Die Mitochondrien liegen in der Nähe von myelinähnlichen Körpern; ihre Außenmembran ist stellenweise vakuolig vorgewölbt. Die axonartigen Fortsätze enthalten viele längsorientierte Mikrotubuli. 4. Die langen Fortsätze der gliaartigen Zellen umhüllen die Parenchymzellen und die extrinsischen Axone meist in mehreren Schichten. Es gibt aber auch Bereiche, in denen vor allem die Fortsätze der Parenchymzellen und die extrinsischen Axone nackt sind. 5. Das Organ ist gegen das umgebende Hämocoel von einer dicken, lamellierten Stromahülle abgegrenzt. Auch Interzellularräume sind mit Stroma gefüllt. 6. Das Organ wird mit der Cerebraldrüse einiger Chilopoden und gewissen endokrinen Organen anderer Diplopoden und Insekten verglichen.
    Notes: Summary 1. The paired organ of Gabe of Schizophyllum sabulosum is situated in the lateral clypeolabrum. It is innervated by axons of the medial labral nerve, which divides in several branches before reaching the organ. 2. Axons extend from neurosecretory cells of the protocerebrum and contain neurosecretory droplets, which are almost ellipsoid and about 1,200 Å in diameter. The axons terminate in the organ and constitute its extrinsic elements. 3. In addition, there are two types of intrinsic cells: (1) parenchyma cells with axon-like processes and (2) glia-like cells. The parenchyma cells produce secretory material in the form of opaque vacuoles, which are clearly larger than the neurosecretory granules. The preponderantly vesicular endoplasmic reticulum is conspicuous. Also characteristic are the mitochondria, whose superficial membranes are expanded locally, and which lie in the near vicinity of myeline-like bodies. The axon-like processes contain many microtubuli oriented in longitudinal direction. 4. The slender processes of the glia-like cells envelop both parenchyma cells and extrinsic axons usually in several layers; but there are also regions in which the processes of the parenchyma cells and, above all, the extrinsic axons are naked. 5. The organ is delimited from the surrounding hemocoele by a thick laminated stroma. Intercellular spaces are also filled with stroma. 6. The organ is compared with the cerebral gland of some chilopods and with certain endocrine organs of other diplopods and insects.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00307017
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    The coxal glands of geophilomorpha (chilopoda): Organs of osmoregulation (1977)
    Springer
    Cell & tissue research 182 (1977), S. 247-251 
    Details
    ISSN: 1432-0878
    Keywords: Coxal organs ; Water transport ; Geophilomorpha ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The organs terminating at the coxal pores of the tug-legs of Geophilomorpha are not repugnatorial glands, but possess typical transport epithelia with deep apical and basal infoldings of the cell membranes, between which numerous large mitochondria are located. Many transport vesicles are found in the basal region but fewer in the apical cytoplasm. The apex is characterized by bundles of longitudinally oriented microtubules, sparse endoplasmic reticulum and free ribosomes. Single neurosecretory axons with synaptoid areas are scattered among the cells. It is suggested that the coxal organs have a diuretic function in moist habitats and an antidiuretic effect in arid environments. The “switch-over” is evidently controlled by a neuroendocrine mechanism.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00220593
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    The relationship between nuclear DNA content in salivary gland tumors and prognosis (1989)
    Springer
    European archives of oto-rhino-laryngology and head & neck 246 (1989), S. 328-332 
    Details
    ISSN: 1434-4726
    Keywords: Salivary gland tumors ; DNA assessment ; Prognosis ; Acinic cell tumor ; Mucoepidermoid tumor
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Differences in prognosis between salivary gland mucoepidermoid tumors and acinic cell tumors were compared by means of conventional histopathological grading and nuclear DNA content which was assessed cytochemically by a scanning cytophotometric procedure. The mucoepidermoid tumors were found to show a stronger correlation between histopathological grading and prognosis than did the acinic cell tumors. By using DNA quantification, valuable additional information could be obtained for predicting the behavior of the mucoepidermoid tumors, whereas there was no correlation between DNA content and prognosis for the acinic cell tumors. Regarding the relatively “benign” clinical course of most mucoepidermoid tumors, the term “tumor” — as proposed by the World Health Organization's classification — seems appropriate. In contrast, the more severe clinical courses of the acinic cell tumors justify the use of the term “carcinoma” instead.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00463587
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...