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  • diabetes  (2)
  • DNA adducts  (1)
  • Dietary carbohydrate  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Mutation Research/Environmental Mutagenesis and Related Subjects 292 (1993), S. 113-122 
    ISSN: 0165-1161
    Keywords: Antibody ; DNA ; DNA adducts ; ELISA ; ^3^2P-postlabelling analysis ; anti-Benzo[a]pyrene-diol-epoxide-DNA antibody analysis
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-0428
    Keywords: Glycaemic index ; leguminous seeds ; low blood glucose rise ; diabetes ; diabetic diet ; fat ; sugars ; protein
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Recently diabetic patients have been encouraged to increase their carbohydrate intake, but exact details of which foods to use are lacking. To determine whether sufficiently large differences existed to justify more specific dietary advice, we compared the glycaemic responses to 50 g carbohydrate portions of different foods, taken as breakfast test meals by groups of five to seven diabetic patients. Two-to threefold differences were seen amongst the 15 foods tested. The glycaemic responses for spaghetti, ‘All-bran’, rice and beans were significantly below those for bread, while ‘Cornflakes’ were above. Factors predicted to influence this were without effect, including: substituting wholemeal for white bread, increasing substantially the simple sugars (using ‘All-bran’ or bananas instead of wholemeal bread) and doubling meal protein by adding cottage cheese to bread. Paired comparisons of the glycaemic response to the five legumes with those of the seven other starchy foods (breads, spaghetti, rice, Cornflakes, oatmeal porridge and potatoes) showed that the mean peak rise in blood glucose concentration and mean area under the glucose curve after beans were 23 and 28% lower, respectively, than the mean for the other foods (p 〈 0.001). Such results suggest a potentially valuable role for dried leguminous seeds in carbohydrate exchanges for individuals with impaired carbohydrate tolerance. These large differences in the blood glucose response to different food cannot at present be predicted directly from tables of chemical composition. Nevertheless, physiological testing may both aid in understanding the factors responsible and help selection of the appropriate carbohydrate foods for the diabetic diet.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-0428
    Keywords: Digestion in vitro ; post-prandial glycaemia ; rate of absorption ; dietary fibre ; dietary carbohydrate ; diabetes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The amount of carbohydrate released at 1 and 5 h by digestion in vitro of 2 g carbohydrate portions of 14 foods by human digestive juices was compared with the area under the 2-h blood glucose response curve when 50 g carbohydrate portions were fed to groups of five to ten healthy volunteers. A significant relationship was found between the amounts of sugars and oligosaccharides liberated at 1 and 5 h and the food blood glucose area expressed as a percentage of the blood glucose area for 50 g glucose (r=0.8627 and 0.8618, p〈0.001). A significant relationship was also found between the glycaemic index and the food fibre content (p〈0.02) and between the glycaemic index and the glucose trapping capacity of the foods (p〈0.05). Legumes as a group liberated 56% less sugars and oligosaccharides (p〈0.01) than the eight cereal foods over 5 h. It is suggested that such studies in vitro may help to identify food of use for diabetic patients, and at the same time throw further light on factors which affect post-prandial glycaemia.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    European journal of applied physiology 67 (1993), S. 309-314 
    ISSN: 1439-6327
    Keywords: Supramaximal exercise ; Dietary carbohydrate
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The present investigation examined the influence of dietary carbohydrate (CHO) on the performance of supramaximal intermittent exercise. A group of 14 moderately trained male students [mean age 21.0 (SD 1.6) years] completed a maximal oxygen consumption test and two identical ‘maximal interval tests’ (MIT, and MIT2) over a 10-day experimental period. Each MIT involved five 60-s all-out periods of cycling (against 0.736 N · kg−1 body mass), with each period separated by 5 min of passive recovery. All subjects consumed a moderate CHO diet for 3 days preceding MIT1 (55.3% of energy intake as CHO) and were then randomly assigned to either a high CHO (83%), moderate CHO (58%) or low CHO (12%) diet for the 3 days separating MIT1 and MIT2. All food and drink consumed during the experimental period was weighed and recorded for later dietary analysis. Measurements of work done, exercise oxygen consumption ( $$\dot V$$ O2), venous blood pH, plasma lactate and plasma glucose concentrations were compared between interval tests. Independent Student's t-tests revealed that the 5.6% increase in total work done recorded by the high CHO group and the 2.3% increase by the moderate CHO group between MIT1 and MIT2, were significantly different to the 5.4% decrease in performance recorded for the low CHO group (P〈0.001 and P〈0.01, respectively). No significant differences in performance changes was found between the high and moderate CHO groups; 10 subjects in each of these groups would have been necessary to attain significance at the 0.05 level using the same procedures. No changes in $$\dot V$$ O2, venous blood pH, plasma lactate or glucose concentrations were found among the groups. These data showed that when compared to a low CHO diet, a moderate/high intake of dietary CHO could at least maintain the performance of supramaximal intermittent exercise. The results emphasise the importance of dietary CHO for athletes whose activities involve repeated periods of very high intensity exercise.
    Type of Medium: Electronic Resource
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