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  • thermal conductivity  (4)
  • Gene expression  (3)
  • Physics  (3)
  • DNA ploidy  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Evaluation of the expression of the cationic peptide gene in various types of leukocytes
    Amsterdam : Elsevier
    FEBS Letters 302 (1992), S. 279-283 
    Details
    ISSN: 0014-5793
    Keywords: Antimicrobial peptide ; Cationic peptide ; Gene expression ; Ginea pig ; In situ hybridization ; Leukocyte
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0014-5793(92)80459-T
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Analysis of subclonal expansion of colorectal carcinomas by flow cytometry (1999)
    Springer
    Virchows Archiv 434 (1999), S. 437-441 
    Details
    ISSN: 1432-2307
    Keywords: Key words Subclonal expansion ; DNA ploidy ; Colorectal carcinoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  DNA heterogeneity of colorectal carcinomas has been investigated by flow cytometry; most studies have focused on the clinical usefulness of DNA ploidy analysis. Since cancers consist of predominant subclones with proliferative advantage due to clonal expansion, we attempted to analyse the clonal expansion of colorectal carcinomas within a tumour by measuring DNA ploidy. The DNA ploidy and heterogeneity of multiple fresh samples obtained from 164 colorectal adenocarcinomas were analysed by flow cytometry. Each tumour was divided into an average of six specimens, which were analysed separately. For 146 of the tumours (89%) at least one DNA aneuploid population was found within the cancer tissue examined. DNA multiploidy was detected in 26 cases (17.8%) among the cancers with aneuploidy. Based on the DNA index (DI), hypertriploid aneuploidy (1.7〈DI〈1.8) was found most frequently in the aneuploid colorectal cancers examined. DNA ploidy heterogeneity was seen in 75 (51.4%) of the DNA aneuploid tumours. There were only 3 cases with more than three subclones including a diploid line. The present results indicate that colorectal carcinomas consist of a few dominant subclones and have a DNA content (hypertriploid aneuploid) that confers a proliferative advantage.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004280050363
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Expression of p53 and flow cytometric DNA analysis of isolated neoplastic glands of the stomach: an application of the gland isolation method (1995)
    Springer
    Virchows Archiv 426 (1995), S. 557-562 
    Details
    ISSN: 1432-2307
    Keywords: Gastric cancer ; p53 immunostaining ; Gland isolation method ; DNA ploidy ; Flow cytometry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The expression of p53 was studied immunohistochemically in combination with the DNA ploidy pattern by gland isolation in 97 alcohol-fixed gastric lesions. A polyclonal antibody, CM-1, was applied to the paraffin-embedded sections in this study. Overexpression of the p53 protein was found in 73.2% of 41 well or moderately differentiated gastric carcinomas and 52.2% of 23 cases with poor differentiation (P〈0.05). Immunoreactivity of p53 was also detected in isolated cancerous glands. No p53 immunoreactivity was detected in benign gastric lesions including adenomas, hyperplastic polyps and regions of intestinal metaplasia. In addition, flow cytometric DNA analysis was performed on isolated glandular epithelium adjacent to the portions used for immunostaining. DNA aneuploidy (DA) was detected in 85.7% of the well or moderately differentiated carcinomas and 42.9% of those with poor differentiation (P〈0.05). There was a positive correlation between DA, p53 positivity and the presence of regional lymph node metastasis, but not with other clinicopathological variables. In spite of the limited applicability of this method to poorly differentiated gastric cancer, we found that immunostaining and flow cytometry in combination with the gland isolation method facilitates analysis of gastric carcinogenesis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00192109
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  • 4
    Electronic Resource
    Electronic Resource
    Studies on ras proteins. Catalytic properties of normal and activated ras proteins purified in the absence of protein denaturants
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/Gene Structure and Expression 949 (1988), S. 97-109 
    Details
    ISSN: 0167-4781
    Keywords: (E. coli) ; (ras gene) ; GDP exchange ; Gene expression ; Kinetics ; Second messenger ; ras protein
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0167-4781(88)90059-0
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  • 5
    Electronic Resource
    Electronic Resource
    Gene expression of tumour necrosis factor-α (TNF-α) and heat-shock protein (HSP) 70 in patients with BehÇet's disease (1993)
    Springer
    Archives of dermatological research 285 (1993), S. 505-508 
    Details
    ISSN: 1432-069X
    Keywords: Gene expression ; TNF-α ; HSP70 ; BehÇet's disease
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00376825
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  • 6
    Electronic Resource
    Electronic Resource
    Measurement of the thermal conductivity of molten InSb under microgravity (1991)
    Springer
    International journal of thermophysics 12 (1991), S. 783-790 
    Details
    ISSN: 1572-9567
    Keywords: InSb ; microgravity ; molten InSb ; thermal conductivity ; transient hot-wire method ; space experiment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Thermal conductivity of molten InSb was measured on board the TEXUS-24 sounding rocket by the transient hot-wire method using the originally designed thermal conductivity measurement facility (TCMF). Measurements made through this facility were affected by natural convection on the ground. This natural convection was confirmed to be sufficiently suppressed during a microgravity environment. The thermal conductivity of molten InSb was 15.8 and 18.2 W·m−1·K−1 at 830 and 890 K, respectively.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00502405
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  • 7
    Electronic Resource
    Electronic Resource
    Measurement of the thermal conductivity of molten semiconductors (1988)
    Springer
    International journal of thermophysics 9 (1988), S. 933-940 
    Details
    ISSN: 1572-9567
    Keywords: alumina ; high temperature ; InSb ; thermal conductivity ; transient hot-wire method
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The thermal conductivity of molten InSb in the temperature range between 800 and 870 K was measured by the transient hot-wire method using a ceramic probe. The probe was fabricated from a tungsten wire printed on an alumina substrate and coated with a thin alumina layer. The thermal conductivity was found to be about 18 W· m−·K−at the melting point and increased moderately with increasing temperature. The thermal conductivity of alumina used as the substrate for the probe was also measured in the same temperature range.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01133261
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  • 8
    Electronic Resource
    Electronic Resource
    Thermophysical properties data on molten semiconductors (1992)
    Springer
    International journal of thermophysics 13 (1992), S. 1061-1084 
    Details
    ISSN: 1572-9567
    Keywords: density ; GaAs ; GaSb ; Ge ; high temperature ; InP ; InSb ; molten state ; semiconductors ; Si ; surface tension ; thermal conductivity ; viscosity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Thermophysical properties of molten semiconductors are reviewed. Published data for viscosity, thermal conductivity, surface tension, and other properties are presented. Several measurement methods often used for molten semiconductors are described. Recommended values of thermophysical properties are tabulated for Si, Ge, GaAs, InP, InSb, GaSb, and other compounds. This review shows that further measurements of thermophysical properties of GaAs and InP in the molten state are required. It is also indicated that a very limited amount of data on emissivity is available. Space experiments relating to thermophysical property measurements are described briefly.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01141216
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  • 9
    Electronic Resource
    Electronic Resource
    Thermophysical property measurements on molten semiconductors using 10-s microgravity in a drop shaft (1996)
    Springer
    International journal of thermophysics 17 (1996), S. 1191-1201 
    Details
    ISSN: 1572-9567
    Keywords: drop shaft ; levitation ; microgravity ; surface tension ; thermal conductivity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The effectiveness of 10-s microgravity on thermophysical property measurements on molten materials, such as molten semiconductors, is discussed. The thermal conductivity of molten InSb was successfully measured under microgravity conditions on board the German sounding rocket TEXUS and in a drop shaft in Hokkaido, Japan. Surface tension measurements using an oscillating drop method was attempted in low gravity using a parabolic flight of the NASA KC-135 aircraft. Combined levitation and microgravity, which can provide a contamination-free and undercooled condition. is recommended as a novel approach to obtain missing thermophysical property data on undercooled melts of semiconductors.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01442006
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  • 10
    Electronic Resource
    Electronic Resource
    Low-temperature dielectric relaxation in poly(4,4′-oxydiphenylene pyromellitimide) (1984)
    New York : Wiley-Blackwell
    Journal of Polymer Science: Polymer Physics Edition 22 (1984), S. 1399-1405 
    Details
    ISSN: 0098-1273
    Keywords: Physics ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: The effect of end groups on the low-temperature dielectric relaxation in poly(4,4′-oxydiphenylene pyromellitimide) has been studied using three kinds of samples with different content of anhydride end groups. The magnitude of the dielectric loss peak, designated here the V peak, which appears near -40°C at 1 kHz, depends on the content of anhydride end groups. If a sample with few anhydride end groups is allowed to absorb water, a loss peak appears near the temperature region of the V peak, but it disappears after subsequent heating. In contrast, a sample having a larger amount of anhydride end groups exhibits a large V peak which remains even after further heating. We conclude that the —O—portion of the anhydride end groups is responsible for the V peak, though there may be an additional contribution from absorbed water.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/pol.1984.180220804
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