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  • 1
    Electronic Resource
    Electronic Resource
    Epithelial tumours of the adult kidney (1999)
    Springer
    Virchows Archiv 434 (1999), S. 281-290 
    Details
    ISSN: 1432-2307
    Keywords: Key words Renal parenchymal carcinoma ; Renal cell carcinoma ; Classification ; Staging ; Grading
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  The epithelial tumours of the adult kidney, in particular renal cell carcinoma (RCC), are a variety of neoplasms that can be classified by morphology and genotype. Although most are well characterised, typical and less typical tumour variants are recognised. There is evidence to indicate that stage is one of the most important prognostic factors, irrespective of tumour subtype. However, the appropriate handling of nephrectomy specimens is essential for accurate evaluation of diagnostic and prognostic factors in RCC. The problem of how to achieve more objective nuclear grading is still unresolved. The use of diagnostic decision support systems offers the possibility of a flexible approach to this problem, while still utilising morphological criteria. The histopathological analysis remains important, but new techniques of molecular and cell biology will be providing new tools of extraordinary power to sharpen the diagnosis and give it a biological interpretation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004280050343
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Das sog. Endokardmyxom (1978)
    Springer
    Virchows Archiv 380 (1978), S. 221-236 
    Details
    ISSN: 1432-2307
    Keywords: Myxoma ; Endothelia ; Myofibroblasts ; Actomyosin ; Mucopolysaccharides
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Three cardiac Myxomas were studied by light-, immuno-fluorescence and electron microscopy. Acid mucopolysaccharides of the tumour were isolated chromatographically. The surfaces of the “myxomas” were papillary in two cases and smooth in one. The smooth surfaced tumour recurred six months after primary resection; histological specimens were more cellular than those of the papillary tumors and showed nuclear polymorphism and mitoses. The cells of two papillary tumours were identified as endocardial by electron microscopy, however, the cells of the smooth surfaced tumour were typical myofibroblasts. In both types of “myxomas” the cells were rich on cytoplasmic filament that contained acto-myosin. Biochemical investigation failed to reveal any difference between the acid mucopolysaccharide pattern of the two tumour types; isolated mucopolysaccharides being typical for embryonal mesenchymal tissue. The authors agree with Albertini (1963), that “cardiac myxoma” is a misnomer for two different typical endocardial tumours: a true endothelioma and a “special fibroma” (myofibroma or myofibrosarcoma).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00430460
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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