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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    HNO 44 (1996), S. 567-571 
    ISSN: 1433-0458
    Keywords: Schlüsselwörter Arbeitsplatzbelastung ; HNO ; Isofluran ; Stickoxydul ; Key words Anesthetic gases ; Isofluran ; nitrous oxide ; Occupational exposure ; ENT surgery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary During ENT surgical procedures under general anesthesia contamination of the operating room air through waste anesthetic gases seems unavoidable. A resulting chronic low-level exposure to anesthetic gases in subanesthetic concentrations (ml/m3=ppm) may cause various negative health effects. The aim of this study was to quantify possible side effects on operating room personnel. By using a highly sensitive, direct reading instrument for determining contamination leakage from a patient's mouth and resulting concentrations in the breathing zone of the surgeon and anesthetist, levels of isoflurane and nitrous oxide were measured at 2-min intervals during 20 ENT surgical procedures performed under usual workplace conditions. Despite high concentrations of anesthetic at the mouth of each patient, personnel-related mean values remained under recommended threshold values (TLV) of 10 ppm isoflurane. A TLV of 100 ppm nitrous oxide was exceeded in 20% of the operations. Furthermore, a safe TLV for pregnant staff was 25 ppm nitrous oxide. This value was exceeded during nearly all operations (93%) for the group “surgeon”. High leakages at the patient's mouth led to an undesirably high contamination of operating room personnel by nitrous oxide. Although threshold values were mostly not exceeded in available working conditions (i.e., adequate air conditioning and intubation cuff pressure control), present health and safety regulations concerning pregnant women showed that the values of nitrous oxide were still too high to allow such women to work safely in operating rooms during surgery. However, exposure to isoflurane was too slight to classify.
    Notes: Zusammenfassung Bei HNO-ärztlichen Eingriffen unter Allgemeinanästhesie findet eine Kontamination der Operationssaalraumluft durch Narkosegase in subanästhetischen Konzentrationsbereichen (ml/m 3 =ppm) statt. Eine daraus resultierende chronische Exposition kann möglicherweise zu Gesundheitsschäden führen. Ziel dieser Studie war es, die Belastung des Operationspersonals zu quantifizieren. Mittels eines hochempfindlichen, direktanzeigenden Meßgeräts wurde die Kontamination an der Leckagequelle „Mundöffnung des Patienten“ und die daraus für Operateur und Anästhesist resultierende Belastung durch Isofluran und Stickoxydul in 2-min-Intervallen bestimmt. Die Messungen erfolgten unter modernen Arbeitsplatzbedingungen während 20 HNO-ärztlichen Eingriffen unter Allgemeinanästhesie. Trotz hoher Konzentrationen an der Mundöffnung der Patienten blieben die mittleren Belastungen für das operative Personal bezüglich Isofluran unter der Grenzwertempfehlung von 10 ppm. Der Stickoxydulgrenzwert von 100 ppm wurde bei 20% der Eingriffe überschritten. Der für Beschäftigungsverbote für schwangere Frauen maßgebliche Schwellenwert von 25 ppm Stickoxydul wurde für die Personengruppe „Operateur“ bei nahezu allen Eingriffen (93%) überschritten. Leckagen am Beatmungstubus führen zu einer unerwünscht hohen Belastung des operativen Personals mit Stickoxydul. Eine Grenzwertüberschreitung findet wegen moderner Arbeitsbedingungen (Klimatechnik, Cuffdruckkontrolle) in den meisten Fällen nicht statt, sind aber dennoch zu hoch, um eine Tätigkeit gefährdeter Personen (z.B. Schwangere) im Operationssaal (OP) zu gestatten. Die Belastung durch Isofluran ist dagegen als gering einzustufen.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Der Radiologe 37 (1997), S. 159-164 
    ISSN: 1432-2102
    Keywords: Schlüsselwörter Magnetresonanztomographie ; Neugeborene ; Kleinkinder ; Sedierung ; Inhalationsanästhesie ; Key words MRI ; Neonates ; Infants ; Sedation ; Anesthesia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Introduction: Since patient cooperation in neonates and infants up to 5 years is always reduced, deep sedation is usually recommended to obtain constant high-quality images during MRI. According to the widely accepted AAP Guidelines, deep sedation is not always distinguishable from general anesthesia, substantiating the demand for state-of-the-art anaesthesia. This is particularly true in this age group, where pharmacokinetics and pharmacodynamics show wide interindividual variation. In this review we outline the techniques required to provide safe and effective patient care in the unique MRI environment. Choice of drugs and procedure: From the viewpoint of induction time, half-life of action and success rate, we have found that inhalation anesthetics and propofol present clear advantages. Both offer rapid induction and emergence, allowing outpatient examinations in a tight schedule with a reliable sedation state. Tracheal intubation or a laryngeal mask airway is required to supply volatile anesthetics and to secure the airway, since propofol in appropriate doses causes respiratory depression and loss of the protective reflexes. Positive-pressure ventilation is recommended since the reduction of tidal volumes by sedative drugs (including high-dose chloral hydrate, barbiturates) may cause atelectasis and decreased oxygen saturation. Anesthesia machines: Several respirators work well outside a critical magnetic field strength of 10 mT (e. g. Draeger: Titus, Siemens: Servo 900). The use of long low-compliance tubing (4–5 m) allows the respirator to be placed at the distal end of the patient table. Side-stream capnometry and spirometry at the proximal tube connector facilitate compensation for losses in tidal volume due to gas compression. Syringe pumps work properly when kept outside the 10 mT line. Some defibrillators (e. g., Lifepac, Physiocontrol) are approved for use in strong magnetic fields. Monitoring: State-of-the-art monitoring is also attainable for high-risk patients, including invasive pressure measurement. Since wiring without special filters may not cross the HF shield of the examination room, hydraulic and pneumatic systems are used (blood pressure by oscillometry, airway monitoring by side-stream spirometry). Optical fibers are used for pulse oximetry. A telemetric EKG is usually provided by the MRT manufacturer. Because oscilloscopes are distorted by the magnetic field, the monitors are placed outside the examination room. In addition, this eliminates the possibility of erasing the EPROMs contained in most monitors. Personnel: With the setup described, the presence of a second anesthetist within the examination room is superfluous. A second anesthesia team can shorten the time lag between examinations by overlapping induction if a separate anesthesia induction and emergence room is provided. Conclusion: The level of sedation required for MRI in newborn and infants can only be achieved safely and efficiently by general anesthesia performed by trained staff. Complete state-of-the-art anesthesia care can be delivered if appropriate instrumentation is used.
    Notes: Zusammenfassung Um bei der MRT von Neu- und Frühgeborenen sowie Kleinkindern eine konstant hohe Bildqualität zu erzielen, ist wegen der mangelnden Kooperativität mindestens eine tiefe Sedierung erforderlich. Hierfür kommen wegen der meist ambulanten Untersuchung nur kurzwirksame Sedativa oder Hypnotika in Betracht. Benzodiazepine oder Phenothiazinderivate sind eher ungeeignet. Das relativ neue i. v.-Anästhetikum Propofol wirkt in den erforderlichen Dosen meist atemdepressiv. Der Reifezustand und die Grundkrankheit, die einer neuroradiologischen Abklärung bedarf, machen eine Sicherung von Atemwegen, Ventilation und Oxygenierung oft erforderlich. Dies geschieht am besten durch eine endotracheale Intubation, die gleichzeitig die Zufuhr der gut steuerbaren Inhalationsanästhetika erlaubt. Überwachung und Beatmung stellen heute technisch kein Hindernis mehr dar, jedoch sind nur speziell für diesen Einsatzbereich zugelassene Geräte zu verwenden. Auch Intensivpatienten können so sicher untersucht werden. Der erhöhte Personal- und Materialaufwand erscheint durch den Gewinn an Sicherheit gerechtfertigt. Der Untersuchungsablauf wird sogar wesentlich beschleunigt.
    Type of Medium: Electronic Resource
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