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  • Irradiation  (1)
  • Key words: Primary carcinoma of the Fallopian tube – Adjuvant therapy  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Primary Fallopian tube carcinoma — a retrospective survey of 51 cases (1994)
    Springer
    Archives of gynecology and obstetrics 255 (1994), S. 141-146 
    Details
    ISSN: 1432-0711
    Keywords: Fallopian tube carcinoma ; Stage 0 ; Stage I ; Chemotherapy ; Irradiation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objective: To evaluate retrospectively the importance of invasion beyond the basement membrane on overall survival in Fallopian tube carcinoma and its influence on the necessity of postoperative adjuvant therapy (stage 0 vs. stage I).Design: In a nationwide analysis the data of 51 patients were evaluated. The participating departments provided the study center with histologic specimens. A re-staging was done according to the FIGO-classification for Fallopian tube carcinomas. Stage 0 patients received no further postoperative therapy, in stage I patients were devided in 2 groups to evaluate the impact of postoperative adjuvant therapy (chemotherapy vs. irradiation).Results: Patients of stage 0 had a significantly better prognosis than patients of stage I (p=0.035). Stage I patients treated by irradiation showed a significantly better prognosis than patients treated by chemotherapy (p=0.017).Conclusion: Tumour penetration through the basement membrane causes prognosis to deteriorate significantly (5-year survival rate about 50% in stage I). Postoperative therapy is thus indicated with stage I disease. Irradiation seems to give better results than chemotherapy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02390941
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Evaluation of adjuvant therapy after surgery for primary carcinoma of the Fallopian tube (1994)
    Springer
    Archives of gynecology and obstetrics 255 (1994), S. 19-24 
    Details
    ISSN: 1432-0711
    Keywords: Key words: Primary carcinoma of the Fallopian tube – Adjuvant therapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Objective: To evaluate the impact of postoperative therapy (chemotherapy vs. irradiation) on overall survival. Design: A nationwide retrospective analysis. Setting: Hanusch-Krankenhaus, Department of Gynaecology. Subjects: 115 patients with histologically proved primary carcinoma of the Fallopian tube: 49 received six treatment cycles of a cis-platinum regimen (group I), 24 patients were treated by full irradiation using 50 Gray minimum (group II). The two groups had a similar distribution of stage I and II; in the more advanced stages chemotherapy was the predominant method of treatment. Results: The five-year survival rate was 53% for women receiving irradiation as against 27% for those given cis-platinum. If the analysis was restricted to those patients with comparable stage I and stage II lesions, the p-value (0.07) was of borderline significance. There was no advantage in adding abdominal to pelvic irradiation (P=0.62). Conclusions: Stage I and stage II carcinoma is probably better treated postoperatively by radiotherapy than chemotherapy. Chemotherapy may have more therapeutic potential in patients with more advanced lesions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004040050020
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
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