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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Der Ophthalmologe 97 (2000), S. 788-791 
    ISSN: 1433-0423
    Keywords: Schlüsselwörter Augeninnendruck ; Tonometer ; Kaninchen ; Keywords Intraocular pressure ; Tonometer ; Rabbits
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Abstract Purpose. To assess use of the tonometer ProTon for measuring intraocular pressure in rabbits. Materials and methods. Eleven chinchilla-bastard rabbits were measured under standardized conditions with the applanation tonometer ProTon for 62±15 days. One rabbit was excluded because of intensively defensive reactions. Results. Intraocular pressure in the ten rabbits was 12.15±3.63 mmHg in the right eye and 12.11±3.52 mmHg in the left eye. Conclusion. Intraocular pressure can be measured reliably over a long period with the applanation tonometer ProTon. It is therefore suitable for determining intraocular pressure in experimentally induced glaucoma in rabbits.
    Notes: Zusammenfassung Fragestellung. Untersuchung des lageunabhängigen Applanationstonometers ProTon im Tiermodell. Material und Methoden. Elf Chinchilla-Bastard-Kaninchen wurden unter standardisierten Bedingungen über einen Zeitraum von 62±15 Tagen mit dem ProTon-Applanationstonometer (Fa. Tomey, Deutschland) untersucht. Ergebnisse. An 10 Kaninchen wurden am rechten Auge ein Augeninnendruck von 12,15±3,63 mmHg und am linken Auge ein Augeninnendruck von 12,11±3,52 mmHg gemessen. Ein Kaninchen musste wegen massiver Abwehrreaktionen ausgeschlossen werden. Diskussion. Mit dem Applanationstonometer ProTon konnten über einen längeren Zeitverlauf hinweg zuverlässige Augeninnendruckwerte erhoben werden. Damit eignet es sich zur Druckmessung bei experimentell induzierten Glaukomen bei Kaninchen.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Documenta ophthalmologica 75 (1990), S. 83-95 
    ISSN: 1573-2622
    Keywords: adaptation ; cat ; rod ; cone ; extracellular recording ; ganglion cell ; rod-cone interaction ; sensitization
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Extracellular ganglion cell responses were recorded to investigate mechanisms of light adaptation. Monochromatic test spots (575 nm) were projected onto the receptive field center of off-center cells and superimposed on a steady blue-green Ganzfeld background (Schott Filter BG 28), the strength of which was increased in steps of 0.5 log units to adapt rods. Response vs. log intensity functions were determined over a range of 7 log units of test light irradiance at each background level. At higher adaptation levels response thresholds followed the typical Weber function. Surprisingly at lower adaptation levels the sensitivity of the cell increased by about 0.7 log units, most markedly in a range of 1 log unit of moderate light adaptation when the background was changed from dark to the dimmest detectable background (10−5lm/m2). In the dark-adapted state a small off-response of long latency (40–100ms at 102 quanta · s−1 · μm−2) is observed at low rod stimulating test light irradiances. A transition to a cone-dominated transient response of 2 to 5 ms duration occurred at high intensities (105 quanta · s−1 · μm2). At mesopic levels the two responses seem to cancel each other, rendering a delayed off-response that is probably the result of rod-cone interaction. As in psychophysics, saturation can be observed at very high background intensities (106 quanta · s−1 μm−2). These data suggest interactions between rods and cones that determine the sensitivity of cat retinal ganglion cells at low levels of adaptation for suprathreshold stimuli.
    Type of Medium: Electronic Resource
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