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  • Key words Prostate cancer  (3)
  • Photoelectric plethysmography  (3)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    International journal of clinical oncology 5 (2000), S. 334-336 
    ISSN: 1437-7772
    Keywords: Key words Prostate cancer ; IgE myeloma ; Asymptomatic
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract An unusual case of the simultaneous occurrence of prostate cancer and IgE myeloma is reported. A 74-year-old man with urinary disturbance and elevated serum prostate-specific antigen level, of 7.4 ng/ml, showed Bence-Jones protein in the urine. Immunoelectrophoresis of the serum showed elevation of IgE kappa monoclonal protein. Radical prostatectomy was performed as a curative therapy for T1c, Gleason 3-2 prostate cancer. The patient has remained free of progression of both the myeloma and the prostate cancer for 26 months after the initial diagnosis.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1437-7772
    Keywords: Key words Prostate cancer ; Systematic biopsy ; Transrectal ultrasonography ; Prostate-specific antigen ; T1c cancer
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Background. Random systematic biopsy is widely utilized for the diagnosis of prostate cancer. The standard method seems to be transrectal ultrasonography (TRUS)-guided sextant transrectal biopsy. In this study, the results of a TRUS-guided transperineal technique were evaluated. Methods. Between 1993 and 1996, 102 patients were diagnosed with prostate cancer by random systematic transperineal biopsy. Eight cores (four from the ventral side and four from the rectal side) were taken from each patient while the longitudinal section was monitored by TRUS. The lengths of the whole core and the cancerous lesion were measured in each biopsy specimen. The results of systematic biopsy were examined in relation to the findings of digital rectal examination (T category), histological grade, clinical stage, and serum level of prostate-specific antigen (PSA). Results. The number of positive cores increased with the T category. The percentage of cancers in the biopsy specimens also increased according to T category. In patients without metastasis, there was a weak correlation between the level of serum PSA and the cube of the total lengths of cancerous lesions in the biopsy specimens. Nonpalpable T1 cancers had more positive cores and a greater percentage of cancer on the ventral side, while in palpable cancers, cancerous tissues were found more often and at a greater incidence on the rectal side. Conclusion. There was a correlation between the clinical stage of prostate cancer and the pathological findings of random systematic transperineal biopsy under TRUS guidance.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    International journal of clinical oncology 5 (2000), S. 345-354 
    ISSN: 1437-7772
    Keywords: Key words Prostate cancer ; Chromosome ; Loss of heterozygosity ; Tumor suppressor gene ; Metastasis suppressor gene
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Cytogenetic, molecular cytogenetic, and molecular studies of prostate cancer have produced a large volume of data about chromosomal loci that are aberrant in prostate cancer. The cumulative data on prostate cancer reveal allelic losses on chromosome arms 2q, 3p, 5q, 6q, 7q, 8p, 9p, 10p, 10q, 11p, 11q, 12p, 13q, 16q, 17p, 17q, 18q, and 21q, but there is a great deal of variability between studies. In most cases, the frequency of allelic loss is higher in metastatic tissues or hormone-refractory tumors than in primary tumors. There also seem to be discrepancies in the genetic findings depending on methods employed. Molecular genetic studies, using polymerase chain reaction (PCR) analysis of microsatellite markers, demonstrated allelic loss at 7q31.1, whereas fluorescence in situ hybridization analysis showed a gain at the same region. Com-mon sites of allelic loss that are consistently observed by various methods seem to exist on chromosome arms 8p, 10q, 13q, and 16q. PTEN/MMAC1 has been identified on 10q23.3 and was found to be frequently mutated in advanced prostate cancer. Other regions are also considered to harbor genes associated with the development and progression of prostate cancer, and these could be included in the diagnostic methods for the substaging of prostate cancer.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Medical & biological engineering & computing 24 (1986), S. 549-554 
    ISSN: 1741-0444
    Keywords: Finger arterial pressure ; Indirect diastolic pressure ; Photoelectric plethysmography ; Volume oscillometric method
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Medical & biological engineering & computing 27 (1989), S. 130-136 
    ISSN: 1741-0444
    Keywords: Diastolic pressure ; Finger arterial pressure ; Indirect sphygmomanometry ; Photoelectric plethysmography ; Pressure/volume relation ; Vibration method ; Volume oscillometric method
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract Diastolic pressure Pd was indirectly measured by vibrating a finger artery with a 10 Hz sinusoidal pressure variation during a gradual increase (or decrease) in occlusive cuff pressure Pc. Pulsatile arterial volume changes on which sinusoidal variations are superimposed were detected by a transmitted infra-red photoelectric plethysmograph (TIPP). It is known that volume change in an artery shows a maximum amplitude at the transmural pressure Pt level equal to 0 mm Hg due to the nonlinear viscoelastic properties of the arterial wall. For the same reason, the amplitude of the sinusoidal volume variation reached its maximum at the end-diastolic phase, when Pc was controlled to be exactly equal to Pd. The indirect Pd values determined from Pc were compared with those simultaneously measured by a direct method in rabbit forelegs and by the volume-compensation method in human fingers. Using the principle of the volume oscillometric method systolic and mean pressures were also determined by this system.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Medical & biological engineering & computing 24 (1986), S. 585-590 
    ISSN: 1741-0444
    Keywords: Mean capillary pressure ; Microcirculation ; Noninvasive estimation ; Preand postcapillary resistance ratio ; Photoelectric plethysmography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract A noninvasive method for estimating the mean capillary pressure Pcap and the pre-and postcapillary resistance ratio Rv/Ra in human fingers is described. Volume change in a finger segment was detected with a transmittance-type infra-red photoelectric plethysmograph during a gradual and linear increase in occluding cuff pressure. There was an inflection point in the volume curve which would be produced by the difference in the compliance between the arterial and venous vascular bed in the segment. This transitional point was assumed to represent the complete compression of the venous vascular bed at the cuff pressure level. Thus Pcap was defined as the cuff pressure corresponding to the inflection point. Rv/Ra was calculated from the Pcap, the venous pressure Pv and the mean arterial pressure Pam. The latter two pressures, Pv and Pam, were also indirectly and simultaneously measured by the compression pressure of another cuff and by our new type of volume oscillation method, respectively. The values of Pcap and Rv/Ra were in good agreement with those reported by other investigators.
    Type of Medium: Electronic Resource
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