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  • Methamphetamine Rat  (1)
  • Sex Differences  (1)
  • 1
    ISSN: 1432-2072
    Keywords: Isolation ; Sex Differences ; Chlordiazepoxide ; Methylphenidate ; Exploration ; Locomotion ; Rearing
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Effects of two doses each of chlordiazepoxide and methylphenidate on exploration, locomotion and rearing were observed in isolated and grouped male and female rats. Sex of the animals determined the effects of both drugs on rearing, and of chlordiazepoxide on preferences for the novel half of an exploration box. Drug administration seemed to abolish initial sex differences on the former response. Locomotion of isolated and grouped animals was also differentially affected by chlordiazepoxide. These findings emphasised the need to take genetic and environmental factors into account when considering the effects of psychotropic drugs on exploratory behaviour.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Psychopharmacology 32 (1973), S. 81-84 
    ISSN: 1432-2072
    Keywords: Sociability ; Photographs ; Chlorpromazine ; Methamphetamine Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Using a time-sample photographic method three measures of sociability showed, contrary to some previous findings, rats administered chlorpromazine (3 mg/kg) to be more sociable than those treated with methamphetamine (2 mg/kg) or isotonic saline. Saline animals were more sociable than amphetamine-treated subjects on two measures. This illustrative study demonstrates that variables influencing sociability results may include social conditions in the cage, post-injection and test environments, and the measure employed.
    Type of Medium: Electronic Resource
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