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  • Parenchymal pattern  (1)
  • Schlüsselwörter M. Crohn • MRT bei M. Crohn • Enteroklyse • MRT  (1)
  • 1
    ISSN: 1432-1084
    Keywords: Key words: Breast ; Parenchymal pattern ; MR imaging ; Contrast enhancement ; MR mammography ; Menstruation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Magnetic resonance mammography (MRM) provides data regarding the nature of tumours based on contrast medium dynamics; fibrocystic changes in the breast, however, may lead to false-positive results. This study investigated whether the contrast medium dynamics of fibrocystic changes are dependent on the menstrual cycle. Twenty-four patients with palpable lumps but normal mammographies and ultrasound studies were examined. The MRM technique was performed during the first and second part of the menstrual cycle using a FLASH 3D sequence, both native and at 1, 2, 3 and 8 min after intravenous application of 0.15 mmol/kg body weight of gadodiamide. The calculated time–intensity curves were evaluated based on the following criteria: early percentage of contrast medium uptake in relation to the native value; formation of a plateau phenomenon after the second minute; the point of maximal contrast medium uptake; and calculation of the contrast enhancing index. During the second half of the menstrual cycle, a generally greater contrast medium uptake was observed. Nevertheless, when further diagnostic criteria, such as continuous contrast medium increase as a function of time, were considered, there was no increased rate of false-positive findings. The phase of the menstrual cycle may affect the specificity of the examination, if only the quantitative contrast medium uptake and the percentage of contrast medium uptake in the first 2 min are considered. A control MRM during the other half of the cycle may then be indicated and additional diagnostic criteria may improve specificity.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-2102
    Keywords: Key words Crohns' disease • MRI in Crohns' disease • Enteroclysis • MRI ; Schlüsselwörter M. Crohn • MRT bei M. Crohn • Enteroklyse • MRT
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Trotz der Verbesserung der MR-tomographischen Diagnostik wird die MRT weiterhin nur selten in der Routinediagnostik bei entzündlichen Dünndarmerkrankungen eingesetzt. Ziel der Untersuchung war die Korrelation der Befunde von Enteroklyse und MRT bei Patienten mit bekanntem M. Crohn nach Optimierung der Darmkontrastierung. Ferner wurde untersucht, ob die MRT Zusatzinformationen zur Enteroklyse liefern kann. 60 Patienten im Alter von 17–72 Jahren wurden untersucht. Zunächst wurde eine Enteroklyse in konventioneller Technik durchgeführt, wobei der Methylzellulose in einer Mischung von 1:10 positives orales MR-Kontrastmittel (Magnevist enteral) zugesetzt wurde. Nach Abschluß der Enteroklyse erfolgte die MRT unter Verwendung T1- und T2-gewichteter Sequenzen (Flash 2D vor und nach i. v. Gd-DTPA bzw. TSE) in Atemanhaltetechnik in koronarer und axialer Schnittführung. Die in der Enteroklyse nachweisbaren Schleimhautveränderungen und Stenosenlänge entsprachen einer nachweisbaren Darmwandverdickung bzw. Stenose in der MRT. Mit der MRT konnten bei 28 Patienten Zusatzbefunde wie Fisteln, Abszesse oder Hydronephrosen diagnostiziert werden, oder die Stenose war wegen der überlagerungsfreien Darstellung in der MRT besser beurteilbar als mittels Enteroklyse. Mit der MRT kann ein wesentlicher Beitrag in der Diagnostik von entzündlichen Darmerkrankungen geleistet werden. Grundvoraussetzung scheint vor allem ein hohes Füllungsvolumen des Dünndarmes zu sein, um eine homogene Kontrastierung und gute Distension zu erreichen.
    Notes: Summary In spite of the improved MR-diagnosis of the abdomen, MRI is not used as a routine method for the diagnosis of inflammatory small bowel disease. The aim of this study was – after optimazation of the bowel opacification – the correlation of the findings obtained with enteroclysis and MRI in patients with known Crohns' disease. 60 patients beween 17 and 72 years of age were investigated. First, an enteroclysis was performed in typical manner. The applicated methylcellulosis was blended with positive oral MR contrast media (Magnevist oral, Schering). After enteroclysis, MRI of the abdomen was performed using T1- and T2-weighted breathhold sequences (Flash 2D pre- and postcontrast and TSE) in axial and coronal planes. The lenght of the affected bowel and the stenosis seen with enteroclysis correlated well with the visible thickening of the small bowel wall and the stenosis seen in MRI. Using MRI, additional findings could be obtained in 28 patients, such as fistulas, abscesses or a hydronephrosis, or a better assessment of the stenosis was possible with MRI, because of the avoidance of overshadowing of the affected bowel loop with MRI. A brilliant MR-tomographic imaging of the small bowel is possible under the condition, that the small bowel contrast is optimal. The main prerequisite is a large filling volume of the small bowel to reach a homogeneous contrast and a good distension of the small bowel lumen.
    Type of Medium: Electronic Resource
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