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  • Polymer and Materials Science  (3)
  • rotifers  (3)
  • pharmacokinetics  (2)
  • red blood cells  (2)
  • systemic sclerosis  (2)
  • thromboxane synthetase inhibitors  (2)
Material
Keywords
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 28 (1985), S. 483-483 
    ISSN: 1432-1041
    Keywords: atenolol ; red blood cells ; deformability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1041
    Keywords: theophylline ; aminophylline ; slow release formulations ; bronchial asthma ; pharmacokinetics ; methods of comparison
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The pharmacokinetics of two slow release theophylline preparations “Theo-Dur” (T) containing theophylline only and “Phyllocontin” (P) containing aminophylline have been compared in 12 patients with asthma. Each patient received both treatments in random order. The dose of treatment administered 12 hourly was increased or decreased to produce plasma theophylline concentrations of 10–20 mg/l at clinic visits normally 7 to 8 h after dosing. Pharmacokinetic studies were carried out after at least one week's treatment with this dose. After the first study day patients were crossed over to the second treatment at a dosage providing a similar amount of theophylline. They returned for a second study day after at least one week. Comparison of the dose corrected AUC, time to peak concentrations, within patient coefficients of variation (CV), number of concentration time points falling within 25% of Cmax and percentage fluctuations in plasma concentration showed no significant differences between the two preparations.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-1041
    Keywords: thromboxane synthetase inhibitors ; Raynaud's syndrome ; systemic sclerosis ; UK-38,485 ; ischaemic attacks ; red blood cell rheology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Ten patients with moderate to severe Raynaud's syndrome were recruited into a four week randomised double blind crossover study to compare the efficacy of UK-38,485 50 mg, a new thromboxane synthetase inhibitor with that of placebo. With the doses used there was no significant difference between the two treatment periods in the number, severity and duration of ischaemic attacks, the mean hand temperatures, forearm and digital blood flow and red blood cell rheology.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-1041
    Keywords: thromboxane synthetase inhibitors ; Raynaud’s syndrome ; systemic sclerosis ; UK-38,485 ; ischaemic attacks ; red blood cell rheology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Ten patients with moderate to severe Raynaud’s syndrome were recruited into a four week randomised double blind crossover study to compare the efficacy of UK-38,485 50 mg, a new thromboxane synthetase inhibitor with that of placebo. With the doses used there was no significant difference between the two treatment periods in the number, severity and duration of ischaemic attacks, the mean hand temperatures, forearm and digital blood flow and red blood cell rheology.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 29 (1985), S. 55-59 
    ISSN: 1432-1041
    Keywords: pentoxifylline ; methyl-xanthine ; red blood cells ; filterability ; endothelial cells
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The effects of pentoxifylline on filterability of normal red blood cells (RBCs) and their adhesiveness to cultured endothelial cells were investigated. 1. In a balanced randomized and double blind trial, six healthy volunteers received 400 mg pentoxifylline or matching placebo 2 h before blood samples were taken. Filterability of RBCs of the subject while on pentoxifylline was significantly increased at 25 °C and 18 °C. 2. Lowering of the filteration temperature to 18 °C significantly decreased filterability of RBCs. 3. In vitro studies showed that 12 µg/ml pentoxifylline significantly increased RBC filterability and also partially prevented the effect of decreasing temperature on RBC filterability. 4. 12 µg/ml pentoxifylline significantly decreased the adherence of normal RBCs to cultured endothelial cells. Our results suggest that in addition to increasing filterability of RBCs, pentoxifylline also decreased the adherence of RBCs to endothelial cells and this may contribute to its therapeutic effect.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 23 (1982), S. 435-440 
    ISSN: 1432-1041
    Keywords: erythromycin ; haemodialysis ; dosage adjustment ; pharmacokinetics ; protein-binding
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Erythromycin kinetics were studied in 17 patients with end stage renal failure treated with maintenance haemodialysis and 9 normal volunteers to discover if dialysis patients needed a modified dose. The elimination half life in dialysis patients (on dialysis days) was similar to that reported in normal subjects. Only small amounts of drug appeared in the dialysate, no patient loosing more than 9 mg in one dialysis. Both patients and volunteers had similar plasma concentrations 8 h after the end of a 5-day course. Protein-binding did not change significantly during dialysis and was similar to that reported in normal subjects. We conclude that dialysis patients requiring 1.5 g of erythromycin stearate daily or less can be given normal doses.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Hydrobiologia 208 (1990), S. 141-152 
    ISSN: 1573-5117
    Keywords: rotifers ; Brazil ; coastal lakes ; neotropical ; distribution
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Four relatively rare, two common rotifers and one rotifer new to science are described from some coastal lakes near Rio de Janeiro, Brazil. Each rotifer is described in detail, and several are accompanied by illustrations and mensuration data. Geographic distribution and individual habitats of the rotifers are also discussed. Several species show a larger geographic distribution than previously known.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Hydrobiologia 137 (1986), S. 3-7 
    ISSN: 1573-5117
    Keywords: rotifers ; geographic distribution ; Republic of Korea
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The author gives account of rotifers found at ten locations in the Republic of Korea, and elaborates some detail of specimens encountered with remarks and drawings. Thirty-seven different rotifer species were found, mostly belonging to the Order Monogononta. Twenty-two are new to the species list compiled by Yamamoto (1953). Keratella hiemalis was found for the first time in Asia. To date, one-hundred and two species of rotifers have been found in Korea.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Hydrobiologia 153 (1987), S. 169-174 
    ISSN: 1573-5117
    Keywords: rotifers ; taxonomy ; new species ; Neotropis ; Brazil
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract A new rotifer is described from among samples taken from coastal lakes in southeastern Brazil. Comparisons to related rotifers are made. This new animal belongs to the Hexarthra mira-intermedia species group by way of its general morphological configuration, the number of teeth in the trophi (5), and the two club-shaped caudal appendages (CSCA's). An extremely long dorsal antenna and very long setae extending from the bend in the ventro-lateral arm characterize this animal's speciation.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 18 (1974), S. 2805-2807 
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Examination of the phosphorescence emission form polypropylene shows the lifetime of the emission to be unaffected by a hydroxybenzophenone light stabilizer but significantly shorted by a diamagnetic Ni(II) chelate stabilizer.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
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