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  • 1
    Electronic Resource
    Electronic Resource
    The location of LH-RH neurons in the rat hypothalamus and their pathways to the median eminence (1979)
    Springer
    Cell & tissue research 198 (1979), S. 381-395 
    Details
    ISSN: 1432-0878
    Keywords: LH-RH neurons ; Hypothalamus ; Rat ; Immunohistochemistry ; Radioimmunoassay
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The location of the perikarya of LH-RH neurons in the rat hypothalamus and their pathways to the median eminence were studied by immunohistochemistry and radioimmunoassay after placing stereotaxic electrolytic lesions in several parts of the hypothalamus. The principal location of the cell somata was found to be in the ventral part of the medial preoptic area; their pathways were classified into a main baso-lateral pathway and an accessory descending pathway branching off from the former. The main pathway was found to cross in the vicinity of the corresponding neuronal perikarya. The central median eminence and the dorsal and ventral walls of the tubero-infundibular sulcus of the caudal part of the median eminence are innervated mainly by the baso-lateral pathway. On the other hand, the rostral and most caudal portions of the median eminence are innervated principally by the descending pathway and have a subsidiary dual innervation. The projection of LH-RH neurons to the OVLT is believed to originate from perikarya adjacent to this circumventricular organ.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00234184
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Correlative ontogenetic development of catecholamine- and LHRH-containing nerve endings in the median eminence of the rat (1981)
    Springer
    Cell & tissue research 216 (1981), S. 31-38 
    Details
    ISSN: 1432-0878
    Keywords: Median eminence ; Rat ; Ontogeny ; LHRH ; Catecholamines
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The ontogenetic development of catecholamine (CA)-and LHRH-containing nerve endings in the median eminence of the rat was investigated by combining fluorescence histochemistry and immunohistochemistry in the same tissue section. LHRH-terminals appeared earlier than CA-terminals and were already detectable in the lateral part of the external layer of the central ME on the first day after birth. CA-nerve endings were first seen in a corresponding region of the ME on the seventh postnatal day. At this stage both types of terminals showed the earliest manifestation of a correlative pattern of their distribution. Subsequently the development of both types of nerve endings proceeded rapidly, and at 14 days their distribution pattern corresponded to that in adult animals. The authors conclude that at this stage the CA-neurons play a constant and significant role in the release of LHRH into the portal capillaries. The correlation between both types of nerve endings and the ontogenetic development of the capillary plexuses of the hypophysial portal system is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00234542
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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