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  • estrogens  (1)
  • peripheral blood  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Androstenedione conversion in human peripheral blood lymphocytes (1994)
    Springer
    Bulletin of experimental biology and medicine 117 (1994), S. 516-518 
    Details
    ISSN: 1573-8221
    Keywords: androstenedione ; lymphocytes ; peripheral blood
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The ability of human peripheral blood lymphocytes to convert the androgenic steroid metabolite androstenedione diminishes in women over 45 years old or during menopause. In patients with breast cancer in menopause the ability of lymphocytes to convert androstenedione is enhanced compared with the control. The intensity of conversion in circulating lymphocytes correlates with the blood concentration of sex steroids.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02444305
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Androstenedione conversion in lymphocytes infiltrating breast tumor tissue (1997)
    Springer
    Bulletin of experimental biology and medicine 124 (1997), S. 1008-1010 
    Details
    ISSN: 1573-8221
    Keywords: lymphocytes ; lymphocytic infiltration ; breast cancer ; estrogens
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Lymphocytes infiltrating tumor tissue are capable of androstenedione conversion, which was assessed from3H2O release from tritium-labeled androgen precursor of estrogens 1β-androstenedione. This capacity is higher in menopausal patients than in patients of reproductive age. A tendency to a positive correlation between the intensity of androstenedione conversion in lymphocytes and aromatase activity in tumor tissue is revealed. No relationship between androstenedione conversion in lymphocytes and contamination of the isolated cell suspension with tumor cells is detected.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02446847
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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