ISSN:
1573-8221
Keywords:
lymphocytes
;
lymphocytic infiltration
;
breast cancer
;
estrogens
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract Lymphocytes infiltrating tumor tissue are capable of androstenedione conversion, which was assessed from3H2O release from tritium-labeled androgen precursor of estrogens 1β-androstenedione. This capacity is higher in menopausal patients than in patients of reproductive age. A tendency to a positive correlation between the intensity of androstenedione conversion in lymphocytes and aromatase activity in tumor tissue is revealed. No relationship between androstenedione conversion in lymphocytes and contamination of the isolated cell suspension with tumor cells is detected.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02446847
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