ISSN:
1432-0428
Keywords:
Glucagon-like peptide-1
;
glucagon
;
specific receptors
;
cyclic AMP
;
liver cells
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Glucagon-like peptide-1 does not have specific, high-affinity receptors on rat liver membranes, does not displace glucagon from glucagon receptors on these membranes and does not stimulate the production of cyclic AMP by isolated rat hepatocytes. In the presence of glucagon, high concentrations of glucagon-like peptide-1 do not significantly alter the production of cyclic AMP. Thus, glucagon-like peptide-1 appears unlikely to have a direct action on hepatic carbohydrate metabolism.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00703137
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