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  • 11
    Electronic Resource
    Electronic Resource
    Reflux symptom relief with omeprazole in patients without unequivocal oesophagitis (1996)
    Oxford BSL : Blackwell Science
    Alimentary pharmacology & therapeutics 10 (1996), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background: As many as 50% of patients with reflux symptoms have no endoscopic evidence of oesophagitis. This multicentre study was designed to assess symptom relief after omeprazole 20 mg once daily in patients with symptoms typical of gastro-oesophageal reflux disease but without endoscopic evidence of oesophagitis. Methods: Patients (n=209) were randomized in a double-blind study to receive either omeprazole 20 mg once daily (n=98) or placebo (n=111) for 4 weeks. Symptoms were assessed at clinic visits and using daily diary cards, with patient-completed questionnaires providing additional data on symptoms and on psychological disturbance. Results: On completion, symptom relief favoured omeprazole: 57% of patients on omeprazole were free of heartburn (vs. 19% on placebo), 75% were free of regurgitation (47%) and 43% were completely asymptomatic (14%), each with P〈0.0001. Fewer patients in the omeprazole group required alginate/antacid relief medication (P〈0.05). Symptom relief (time to first heartburn-free day) was more rapid with omeprazole (2 vs. 5 days on placebo; P〈0.01). A greater reduction in anxiety occurred in the omeprazole group (P〈0.05). Conclusion: Omeprazole 20 mg once daily is effective in providing relief of the symptoms typical of gastro-oesophageal reflux disease in patients with essentially normal oesophageal mucosa.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2036.1996.44186000.x
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  • 12
    Electronic Resource
    Electronic Resource
    Omeprazole is more effective than cimetidine for the relief of all grades of gastro-oesophageal reflux disease-associated heartburn, irrespective of the presence or absence of endoscopic oesophagitis (1997)
    Oxford, UK : Blackwell Science Ltd
    Alimentary pharmacology & therapeutics 11 (1997), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background: Previous studies have demonstrated greater efficacy for omeprazole compared with cimetidine in patients with endoscopically verified oesophagitis, but excluded the substantial group of gastro-oesophageal reflux disease (GERD) patients with reflux symptoms but without endoscopic abnormality. This prospective, randomized, double-blind study compared omeprazole and cimetidine in the treatment of GERD-associated heartburn both in patients with symptomatic non-ulcerative oesophagitis and in those with heartburn but without oesophagitis. Methods: A total of 221 patients with heartburn and oesophageal mucosa grade 0 (normal, n = 51), 1 (no macroscopic erosions, n = 52), 2 (isolated erosions, n = 97) or 3 (confluent erosions, n = 21) were randomized to receive double-blind either omeprazole 20 mg daily or cimetidine 400 mg q.d.s. for a period of 4 weeks. Those still symptomatic after 4 weeks of treatment received omeprazole 20 mg daily for a further 4 weeks. Results: There was no correlation between severity of heartburn and endoscopic grade at entry (correlation coefficient = 0.196). After 4 weeks of treatment, the proportion of patients in whom heartburn was controlled (no more than mild symptoms on no more than 1 day in the previous 7) on omeprazole (66%; 74/112) was more than double that on cimetidine (31%; 34/109) (P 〈 0.0001). There was no significant difference between the relief of heartburn in the 47% of patients without unequivocal oesophagitis (endoscopic grade 0 or 1) and in the 53% of patients with erosive oesophagitis (grade 2 or 3) (P = 0.31). Only treatment with omeprazole (P 〈 0.0001) and lower severity of heartburn at entry (P 〈 0.01) were significant in predicting heartburn relief. Amongst those patients requiring an additional 4 weeks of treatment with omeprazole, 67% (54/81) reported that their heartburn was controlled after 8 weeks of treatment. Conclusion: We conclude that omeprazole is superior to cimetidine for the relief of all grades of heartburn in GERD, whether or not the patient has unequivocal endoscopic oesophagitis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2036.1997.00198.x
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  • 13
    Electronic Resource
    Electronic Resource
    Does 40 mg omeprazole daily offer additional benefit over 20 mg daily in patients requiring more than 4 weeks of treatment for symptomatic reflux oesophagitis? (1993)
    Oxford, UK : Blackwell Publishing Ltd
    Alimentary pharmacology & therapeutics 7 (1993), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: This study was designed to establish whether 40 mg omeprazole once daily exhibits sufficient additional efficacy over that of 20 mg omeprazole once daily in patients with symptomatic reflux oesophagitis requiring more than an initial 4-week course of 20 mg omeprazole once daily (o.m.) to warrant routine use of the higher dose. Three hundred and thirteen patients were randomized to receive either 20 mg omeprazole (4 weeks) then 20 mg (second 4 weeks if not both healed and symptom-free after 4 weeks), or 20 mg omeprazole (4 weeks) then 40 mg omeprazole o.m. (second 4 weeks). One hundred and twenty-seven patients were healed and symptom-free after 4 weeks and left the study at that point. Taking the second treatment period in isolation, the healing rate (64%vs. 45%, P 〈 0.02) and relief of heartburn (72%vs. 60%, P 〈 0.002) were greater among patients receiving 40 mg omeprazole o.m., demonstrating the existence of a dose–response relationship for omeprazole. However, on completion, there were no significant differences between the patients randomized to the 20/20 mg (healed 65%, asymptomatic 69%) or the 20/40 mg (healed 74%, asymptomatic 74%: both not significant differences compared with 20/20 mg) regimens. The magnitude of the difference in efficacy between 20 and 40 mg omeprazole in symptomatic reflux oesophagitis is insufficient to warrant the routine use of 40 mg in patients requiring more than 4 weeks' treatment with 20 mg omeprazole o.m.; continued treatment with 20 mg omeprazole for 4–8 weeks is the preferred option.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2036.1993.tb00125.x
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  • 14
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    Progress in Marketing Research (1936)
    New York : Periodicals Archive Online (PAO)
    Journal of marketing. 1:1 (1936:July) 56 
    Details
    ISSN: 0022-2429
    Topics: Economics
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:3142-1936-001-01-000011
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  • 15
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    Progress in Marketing Research (1936)
    New York : Periodicals Archive Online (PAO)
    Journal of marketing. 1:2 (1936:Oct.) 156 
    Details
    ISSN: 0022-2429
    Topics: Economics
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:3142-1936-001-02-000014
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  • 16
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    Allocation of Scarce Consumer's Goods to Retailers (1943)
    New York : Periodicals Archive Online (PAO)
    Journal of marketing. 8:2 (1943:Oct.) 123 
    Details
    ISSN: 0022-2429
    Topics: Economics
    Notes: Wartime Marketing
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:3142-1943-008-02-000001
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  • 17
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    Appraisal of the BLS Index of Wholesale Food Prices in Wartime (1944)
    New York : Periodicals Archive Online (PAO)
    Journal of marketing. 9:1 (1944:July) 32 
    Details
    ISSN: 0022-2429
    Topics: Economics
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:3142-1944-009-01-000005
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  • 18
    Electronic Resource
    Electronic Resource
    Mössbauer Effect of Thulium Compound (1968)
    [s.l.] : Nature Publishing Group
    Nature 218 (1968), S. 1047-1047 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] With this technique we have learnt more about the structure of thulium chelates. We have taken the known C-Tm2O3 type structure as a model and assumed that AjR/12, the difference in nuclear radius between the excited and the ground state, is positive. The natural 100 per cent abundant 169Tm has a ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/2181047a0
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  • 19
    Electronic Resource
    Electronic Resource
    Properties of a special class of doubly stochastic measures (1988)
    Springer
    Aequationes mathematicae 36 (1988), S. 212-229 
    Details
    ISSN: 1420-8903
    Keywords: Primary 28A35, 28A33, 60A10
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Summary A measure μ on the unit squareI } I is doubly stochastic ifμ(A } I) = μ(I } A) = the Lebesgue measure ofA for every Lebesgue measurable subsetA ofI = [0, 1]. By the hairpinL ∪L −1, we mean the union of the graphs of an increasing homeomorphismL onI and its inverseL −1. By the latticework hairpin generated by a sequence {x n :n ∈ Z} such thatx n-1 〈 xn (n ∈ Z), $$\mathop {\lim }\limits_{n \to - \infty } $$ x n = 0 and $$\mathop {\lim }\limits_{n \to \infty } $$ x n = 1, we mean the hairpinL ∪L −1 , whereL is linear on [x n-1 ,x n ] andL(n) =x n-1 forn ∈ Z. In this note, a characterization of latticework hairpins which support doubly stochastic measures is given. This allows one to construct a variety of concrete examples of such measures. In particular, examples are given, disproving J. H. B. Kemperman's conjecture concerning a certain condition for the existence of doubly stochastic measures supported in hairpins.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01836092
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  • 20
    Electronic Resource
    Electronic Resource
    Modes of decomposition of rare earth metal formates and benzoates, enthalpies of transition, and activation energies of decomposition (1974)
    Springer
    Journal of thermal analysis and calorimetry 6 (1974), S. 673-688 
    Details
    ISSN: 1572-8943
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Résumé On a étudié la décomposition des formiates et benzoates de quelques terres rares par ATD, DSC, TG et TGD. On a identifié les produits volatils ainsi que les résidus. On a calculé les énergies d'activation des décompositions et la chaleur des réactions de transition. Les formiates des terres rares donnent comme produits de décomposition volatiles de l'anhydride carbonique et de l'eau, tandis que, dans le cas du benzoate de lanthane, on obtient du benzyle et, probablement, du benzophénone. Les autres benzoates de terres rares fournissent du diphényle comme principal produit volatil. Les trioxydes respectifs forment le résidu final.
    Abstract: Zusammenfassung Der Verlauf der thermischen Zersetzung einiger seltener Erdmetall-Formiate und -Benzoate wurde unter Anwendung der DTA, DSC, TG und DTG-Techniken studiert. Die flüchtigen Produkte und die Rückstände wurden identifiziert. Die Aktivierungsenergien der Zersetzungsvorgänge und die Reaktionswärmen der Übergänge wurden ermittelt. Die Zersetzung der seltenen Erdmetall-Formiate ergab Kohlendioxid und Wasser als flüchtige Produkte, während die Benzoate — im Falle von Lanthan-benzoat Benzyl und wahrscheinlich Benzophenon, im Falle anderer seltener Erdmetall-benzoate Biphenyl als flüchtige Hauptprodukte ergaben. Die entsprechenden Trioxide verblieben als Rückstand.
    Notes: Abstract The modes of decomposition of a few rare earth metal formates and benzoates were studied by the use of DTA, DSC, TG and DTG techniques in air, nitrogen and vacuum. The volatile products and residues were identified. The activation energies of decompositions and the heat of reaction for transitions were calculated. The decomposition of the rare earth metal formates gave carbon dioxide and water as their volatile products and the benzoates gave benzil and probably benzophenone in the case of lanthanum benzoate and biphenyl in the case of other rare earth metal benzoates, as their main volatile products, leaving the corresponding trioxides as their final residues.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01911787
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