ISSN:
1436-2449
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Chemie und Pharmazie
,
Maschinenbau
,
Physik
Notizen:
Summary In vitro studies of controlled release from chitosan membranes were carried out using drugs of different molecular weight. The release rate was measured in water at 37°±0.5°C by determining the amount of drug released by spectrophotometric analysis. It was found that release of acetamide, nicotinamide, sodium benzoate, sodium salicylate, phenobarbital sodium and sodium cefazoline followed zero-order kinetics. The relation between molecular weight and diffusion coefficient was established.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF00297416
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