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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 66 (1988), S. 713-717 
    ISSN: 1432-1440
    Keywords: Cardiac neoplasm ; Myxoma ; Thrombus formation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Neoplasms are rare cardiac findings of which myxomas comprise about 75%. We report of 15 patients, predominantly female (60%) with a mean age of 58.8 years. Male patients (40%) were 20 years younger on average. 80% of these tumors developed in the left atrium fixed to the atrial septum. In 2 patients the right ventricle and in 1 patient the right atrium was involved. No left ventricular or bilateral tumors were found. Clinical findings showed a great variety of symptoms. Often misdiagnosis was established until echocardiography was performed. Major symptoms were dyspnea (80%), elevated erythrocyte sedimentation rate (73%), arrhythmias (53%), lung edema (47%), embolization (40%) and anemia (40%). Pathological examination and tumor genesis are still in discussion. Several theories are reported in literature: a true thrombus, thrombus organization with malignant potential, true neoplasms as well as a familiar myxoma complex may explain clinical and histological features. Our findings did not confirm only one theory but emphasize different possibilities.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular evolution 31 (1990), S. 92-100 
    ISSN: 1432-1432
    Keywords: Repeated sequences ; Retrotransposon proretrovirus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Galago DNA contains a few single copy sequences that are homologous to the human THE 1 family of repeats. Two of these galago loci have been isolated as genomic clones and their structures are compared to the THE 1 consensus sequence. Whereas the human sequence resembles a proretroviral transposon, the galago sequences provide no evidence for a proretroviral sequence organization. The two galago clones share a common repeat sequence, which is homologous to the U5 region of the THE 1 long terminal repeat. Immediately 3′ to this repeat, each galago clone contains sequences that are homologous to mutually exclusive regions of the internal THE 1 sequence. Thus, the human THE 1 sequence can be represented as a mosaic of the two ancestrally related galago loci. The galago loci are transcribed in vivo, so that their conservation in the primate genome could be selected. Human THE 1 repeats apparently resulted by recruiting preexisting cellular sequences via a retrovirally mediated process.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 132-136 (Apr. 1997), p. 1353-1356 
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Zeitschrift für Herz-, Thorax- und Gefässchirurgie 12 (1998), S. 206-209 
    ISSN: 0930-9225
    Keywords: Schlüsselwörter Aortokoronare Re-Bypass-Operation – minimalinvasive Chirurgie – linksventrikuläre Dysfunktion ; Key words Coronary artery bypass grafting – minimally invasive surgery – left ventricular dysfunction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Patients with severely impaired left ventricular pump function, who necessitate redo coronary bypass surgery have to face a considerably increased risk. We report on a patient who underwent redo surgery with minimal invasive techniques without extra-corporeal circulation. Indication and revascularization strategy are illustrated by the case report.
    Notes: Zusammenfassung Eine hochgradige linksventrikuläre (LV) Dysfunktion und eine kardiale Voroperation erhöhen das Operationsrisiko für einen Re-Eingriff beträchtlich. Wir berichten über einen Patienten, bei dem wir eine Re-Operation in minimalinvasiver Operationstechnik ohne Herz-Lungen-Maschine durchführten. Indikation und Strategie zur Revaskularisierung werden anhand dieses Einzelfallberichts dargestellt.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 0930-9225
    Keywords: Schlüsselwörter Schlaf-Apnoe-Syndrom ; Herzchirurgie ; Operationsrisiko ; Anästhesierisiko ; Key words Sleep apnoea syndrome ; cardiac surgery ; anesthetic risk ; operative risk
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary The operative and anesthetic risk of patients suffering from sleep apnoea syndrome is generally considered to be elevated because of frequent concomitant disease such as obesity and hypertension and side effects of sedative, anesthetic and analgesic agents. Cardiac surgery with extracorporeal circulation leads to lung edema and may therefore aggravate complications of the respiratory tract. We performed this study to verify, if the operative and anesthetic risk of patients, suffering from sleep apnoea syndrome and undergoing cardiac surgery, is really elevated.    Between September 1994 and December 1996 ten male patients suffering from sleep apnoea syndrome underwent aortocoronary bypass grafting with extracorporeal circulation. Preoperatively we analyzed symptomatology, predisposing factors, concomitant diseases and medication. Perioperatively we were interested in respiratory and hemodynamic function, anesthetic management and complications beside the common operative parameters.    All patients were obese and four patients were treated medically for hypertension. The anesthetic management was the same as used in other routine cardiac patients. Neither induction of anesthesia nor weaning from the respirator led to respiratory complications. Postoperatively we had to implant an intraaortic balloon counterpulsation in two patients because of left ventricular dysfunction in order to stabilize hemodynamics. We removed it in both patients without complications on the second postoperative day after catecholamine therapy had been stopped.    Patients suffering from sleep apnoea syndrome are not at increased risk for respiratory and hemodynamic complications when undergoing cardiac surgery with extracorporeal circulation.
    Notes: Zusammenfassung Das Operations- und Anästhesierisiko von Patienten mit einem Schlaf-Apnoe-Syndrom wird aufgrund der häufigen Begleiterkrankungen (z.B. Adipositas, arterielle Hypertonie) und den Nebenwirkungen der Sedativa, Anästhetika und Analgetika allgemein als erhöht beurteilt. Bei kardiochirurgischen Eingriffen mit Hilfe der extrakorporalen Zirkulation können respiratorische Komplikationen durch Flüssigkeitseinlagerung in die Lunge aggraviert werden. Wir führten diese Studie durch, um zu untersuchen, ob das Operations- und Anästhesierisiko bei Patienten mit Schlaf-Apnoe-Syndrom, bei denen herzchirurgische Eingriffe mit Hilfe der extrakorporalen Zirkulation erforderlich sind, tatsächlich erhöht ist.    Im Zeitraum vom 1.9.94 bis 31.12.96 wurde bei 10 männlichen Patienten mit einem Schlaf-Apnoe-Syndrom eine aortokoronare Bypass-Operation durchgeführt. Präoperativ wurden die klinische Symptomatik der Patienten, prädisponierende Faktoren, Begleiterkrankungen und Medikation untersucht. Perioperativ interessierten wir uns neben den üblichen operativen Daten besonders für das Anästhesiemanagement, die respiratorischen und hämodynamischen Parameter sowie die Komplikationen.     Alle Patienten waren adipös, bei vier Patienten bestand eine medikamentös behandlungsbedürftige Hypertonie. Das Anästhesiemanagement unterschied sich nicht von dem, das üblicherweise bei Patienten mit herzchirurgischen Eingriffen in unserem Hause angewandt wird. Sowohl während der Narkoseeinleitung als auch während der Entwöhnung vom Respirator und während des weiteren postoperativen Verlaufs traten keine respiratorischen Komplikationen auf. Bei zwei Patienten war die Implantation einer intraaortalen Ballon-Pumpe aufgrund einer postoperativen linksventrikulären Dysfunktion zur hämodynamischen Stabilisierung erforderlich. Bei beiden Patienten konnte diese am zweiten postoperativen Tag nach Beendigung der Katecholamintherapie komplikationslos wieder entfernt werden.    Herzchirurgische Eingriffe unter Zuhilfenahme der extrakorporalen Zirkulation können bei Patienten mit Schlaf-Apnoe-Syndrom ohne erhöhtes Risiko an respiratorischen und hämodynamischen Komplikationen durchgeführt werden.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Zeitschrift für Herz-, Thorax- und Gefässchirurgie 12 (1998), S. 58-61 
    ISSN: 0930-9225
    Keywords: Schlüsselwörter Triton-Tumor – pulmonale Metastasen – Lungenresektion ; Key Words Triton tumor – pulmonary metastasis – lung resection
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary We report on a young patient who underwent multiple thoracic surgical procedures for recurrent pulmonary metastases of a malign Triton tumor with improvement of mid-term outcome. The medical history and the pathological findings of this disease are presented.
    Notes: Zusammenfassung Wir berichten über eine Patientin, bei der aufgrund rezidivierender pulmonaler Metastasierung eines malignen Triton-Tumors mehrere thoraxchirurgische Interventionen in unserer Klinik durchgeführt wurden und eine Überlebensverlängerung der Grunderkrankung erreicht werden konnte. Die Krankengeschichte der Patienten und die pathologischen Merkmale dieser Tumorentität werden dargestellt.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Biochemical and Biophysical Research Communications 151 (1988), S. 512-517 
    ISSN: 0006-291X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Biochemical and Biophysical Research Communications 160 (1989), S. 788-794 
    ISSN: 0006-291X
    Keywords: CP; carrier protein ; E"2; 17β-estradiol ; FCS; fetal calf serum ; GH; growth hormone ; IGF; insulin-like growth factor ; PBS; phosphate-buffered saline
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Nuclear Physics, Section B 194 (1982), S. 319-327 
    ISSN: 0550-3213
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Current Opinion in Genetics & Development 2 (1992), S. 874-882 
    ISSN: 0959-437X
    Keywords: IAP; intracisternal A-particle ; LINE; long interspersed element ; RT; reverse transcriptase ; SINE; short interspersed element ; ^mC; 5-methyl cytosine ; pol III; polymerase III
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology
    Type of Medium: Electronic Resource
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