ISSN:
1436-2449
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
,
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
,
Physics
Notes:
Summary In vitro studies of controlled release from chitosan membranes were carried out using drugs of different molecular weight. The release rate was measured in water at 37°±0.5°C by determining the amount of drug released by spectrophotometric analysis. It was found that release of acetamide, nicotinamide, sodium benzoate, sodium salicylate, phenobarbital sodium and sodium cefazoline followed zero-order kinetics. The relation between molecular weight and diffusion coefficient was established.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00297416
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