ISSN:
1432-0584
Schlagwort(e):
Key words Marginal-zone B-cell lymphoma
;
Splenic lymphoma with villous lymphocytes
;
Hairy-cell leukemia
;
Marginal zone
;
Phenotype
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Medizin
Notizen:
Abstract A particular case of marginal zone B-cell lymphoma (MZBCL) presenting with leukemic lymphocytes is reported. In the present observation, the leukemic cells not only displayed a remarkable morphological fluctuation but also had an unusual phenotype, changing with time. These phenotypic features, which have been functionally investigated by in vitro assays, might simply reflect an activation state depending on the microenvironment. Because of its disconcerting similarities with hairy cell leukemia (HCL) and splenic lymphoma with villous lymphocytes (SLVL), this case relaunches the debate about whether close relationships might exist between the splenic marginal zone, SLVL and HCL.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/s002770050274
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