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Bacillus subtilis genome project: cloning and sequencing of the 97 kb region from 325° to 333deg; (1993)

Glaser, P. ; Kunst, F. ; Arnaud, M. ; [et al.]

Oxford, UK : Blackwell Publishing Ltd

Molecular microbiology 10 (1993), S. 0

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ISSN: 1365-2958

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Biology , Medicine

Notes: In the framework of the European project aimed at the sequencing of the Bacillus subtilis genome the DNA region located between gerB (314°) and sacXV (333°) was assigned to the Institut Pasteur. In this paper we describe the cloning and sequencing of a segment of 97 kb of contiguous DNA. Ninety-two open reading frames were predicted to encode putative proteins among which only forty-two were found to display significant similarities to known proteins present in databanks, e.g. amino acid permeases, proteins involved in cell wall or antibiotic biosynthesis, various regulatory proteins, proteins of several dehydrogenase families and enzymes II of the phosphotransferase system involved in sugar transport. Additional experiments led to the identification of the products of new B. subtilis genes, e.g. galactokinase and an operon involved in thiamine biosynthesis.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1111/j.1365-2958.1993.tb01963.x

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245. Die Arteriosklerose als chirurgische Aufgabe (1975)

Heberer, G. ; Schildberg, F. W. ; Becker, H. M. ; [et al.]

Springer

Langenbeck's archives of surgery 339 (1975), S. 757-757

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ISSN: 1435-2451

Keywords: Arteriosclerosis ; Surgical treatment ; Late results ; Arteriosklerose ; Chirurgische Behandlung ; Spatergebnisse

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Description / Table of Contents: Zusammenfassung Die Spatergebnisse der rekonstruktiven Arterienchirurgie werden an 5245 operierten Kranken der Chirurgischen Universitätskliniken Köln und München (1959–1974) dargestellt. Die Eingriffe bei cerebrovasculärer Insuffizienz (378 Kranke), renovasculärer Hypertonie (257 Kranke) and Angina intestinalis (24 Pat.) ermöglichen bei niedriger operativer Letalität and Morbidität eine Lebensverlängerung, bei Verschlüssen im Aorta-Iliaca-Bereich (2547 Pat.) and am femoro-poplitealen Abschnitt (1440 Pat.) gilt die Erhaltung der Extremität als therapeutisches Ziel. Bei peripheren (303 Pat.) and Aortenaneurysmen (296 Pat.) ist fur ein gutes Behandlungsergebnis der frühzeitige Eingriff vor dem Auftreten von Komplikationen (Thromboembolie bzw. Ruptur) Voraussetzung.

Notes: Summary The long-term follow-up results of reconstructive vascular surgery are demonstrated in 5245 patients operated on in the University Surgical Clinics in Cologne and Munich (1959–1974). With low surgical lethality and morbidity, operative treatment of cerebrovascular insufficiency (378 patients) or renovascular hypertension (257 patients) guarantees longer survival. In cases of aorto-iliacal (2547 patients) and femoropopliteal (1440 patients) occlusion, the object of therapy is the preservation of the extremity. For good results, operative treatment of peripheral and aortic aneurysms should be performed before complications such as thromboembilism or rupture of the aneurysm occur.