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  • 1
    Electronic Resource
    Electronic Resource
    Immunocytochemical localization of the sodium, potassium activated ATPase in knifefish brain (1977)
    Springer
    Journal of neurocytology 6 (1977), S. 571-581 
    Details
    ISSN: 1573-7381
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Results presented in this paper demonstrate the feasibility of using immunocytochemical methods to localize the (Na+ + K+)-ATPase, and its subunits, in the C.N.S. We have shown that in the Black Ghost knifefish,Sternarchus albifrons, the enzyme is located on the plasma membrane of the somata and dendrites of neurons and on the somata and cellular processes of glia. In myelinated axons the enzyme is restricted in localization to those portions of the axolemma not covered by the myelin sheath. The capacity of cell plasma membranes to restrict mobility of functionally important proteins should be considered in models of membrane structure in which lateral mobility of membrane components is considered a major characteristic.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01205220
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Human muscle spindles: Microfilaments in the group IA sensory nerve endingsSupported in part by a grant from the ALS Foundation, St. Paul, Minnesota. (1974)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 180 (1974), S. 521-532 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The fine structure of the group IA sensory nerve endings from normal human muscle spindles was studied in transverse and longitudinal sections. Two arrangements of microfilaments, approximately 75 Å in diameter, were found in each of ten spindles examined. The first was a central aggregate of densely packed filaments. The aggregates were partly surrounded by mitochondria, and were oriented parallel to the longitudinal axis of the sensory ending as it encircled the intrafusal muscle fiber. Individual aggregate filaments of glycerinated endings appeared to react with heavy meromyosin. The second arrangement was a filamentous network in the periphery of the sensory ending profiles. These microfilaments approached and appeared to merge with the surface membrane. They resembled the microfilaments that others have described in growth cones of cultured neurons. Both types of microfilaments are thought to be involved in changing the shape of the sensory endings during stretch and relaxation of the spindle.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091800311
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    Paper (German National Licenses)
    Fulltext
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