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  • 1
    ISSN: 1471-0528
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Summary. Fifty-four patients with advanced ovarian cancer have been treated with combination chemotherapy using cyclophosphamide, adriamycin and cis-platinum. The toxicity of the regimen was manageable but few patients were prepared to tolerate more than 6 months of treatment. Those in complete clinical remission at that time were offered second-look laparotomy and if apparently free of disease, therapy was discontinued. Forty-seven patients could be assessed of whom 33 had had no previous therapy. Twenty-two of these were clinically free of disease after completion of chemotherapy of whom 12 had no detectable disease at second-look laparotomy. Of 14 patients who had failed previous therapy only one remains clinically free of disease. The results in the untreated patients demonstrate the primary importance of bulk reduction at initial laparotomy. The use of the regimen in patients who have failed on previous treatment or in patients with bulk disease seems to be palliative and the toxicity should be assessed in this context.
    Materialart: Digitale Medien
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  • 2
    Digitale Medien
    Digitale Medien
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 66 (1995), S. 833-833 
    ISSN: 1089-7623
    Quelle: AIP Digital Archive
    Thema: Physik , Elektrotechnik, Elektronik, Nachrichtentechnik
    Notizen: To aid in the study of lower hybrid current drive as a means of current profile control, the radial profile and velocity distribution of the fast current-carrying electrons and their time evolution must be known. As part of the recent effort to understand this fast electron transport, a diagnostic has been installed on PBX-M to measure the electron cyclotron emission from the fast electrons. An oblique horizontal view of upshifted cyclotron emission in the midplane can give radial as well as velocity space information about the fast electrons. Emission in X mode frequencies refracted by the right-hand cutoff is radially localized. The observed emission at a specific frequency comes only from the radial region rturn〈r〈r(Bmin), where rturn is the turning point of the ray, and r(Bmin) is given by the condition of the resonance frequency n2(parallel)+(nΩ/ω)2−1≥0. Emission measured by this new diagnostic has been found to be radially localized as predicted. It is also expected that localized moments of the distribution function may be obtained from these data. A superheterodyne receiver at 60–90 GHz has been built which views the plasma through a focusing gaussian lens antenna at a 57° angle to the toroidal magnetic field. Viewing dumps made of SiC on both the inside and outside walls ensure single pass emission. Results from this new diagnostic will be presented. © 1995 American Institute of Physics.
    Materialart: Digitale Medien
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  • 3
    Digitale Medien
    Digitale Medien
    [S.l.] : American Institute of Physics (AIP)
    Physics of Plasmas 3 (1996), S. 4065-4073 
    ISSN: 1089-7674
    Quelle: AIP Digital Archive
    Thema: Physik
    Notizen: It is shown that radial localization of optically thin electron cyclotron emission from superthermal electrons can be imposed by observation of emission upshifted from the thermal cyclotron resonance in the horizontal midplane of a tokamak. A new and unique diagnostic has been proposed and operated to make radially localized measurements of superthermal electrons during lower hybrid current drive on the Princeton Beta Experiment-Modified (PBX-M) tokamak [Bernabei, et al., Phys. Fluids B 5, 2562 (1993)]. The superthermal electron density profile as well as moments of the electron energy distribution as a function of radius are measured during lower hybrid current drive. The time evolution of these measurements after the lower hybrid power is turned off are given and the observed behavior reflects the collisional isotropization of the energy distribution and radial diffusion of the spatial profile. © 1996 American Institute of Physics.
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  • 4
    ISSN: 1089-7674
    Quelle: AIP Digital Archive
    Thema: Physik
    Notizen: With the first injection of neutral beams into the National Spherical Torus Experiment (NSTX) [Ono et al., Nucl. Fusion 40, 557 (2000)], a broad spectrum of fluctuations consisting of nearly equally spaced peaks in the frequency range from about 0.2 to 1.2 times the ion cyclotron frequency was observed. The frequencies scale with toroidal field and plasma density consistently with Alfvén waves. From these and other observations, the modes have been identified as compressional Alfvén eigenmodes (CAE). It has also recently been found that the ratio of the measured ion and electron temperatures in NSTX during neutral beam heating is anomalously high [Bell, Bull. Am. Phys. Soc. 46, 206 (2001)]. To explain the anomaly in the ratio of ion to electron temperature, it has been suggested that the CAE, driven by the beam ions, stochastically heat the thermal ions [Gates et al., Phys. Rev. Lett. 87, 205003 (2001)]. In this paper it is shown through studies of the power balance that stochastic heating of the thermal ions by the observed CAE alone is not solely responsible for the anomaly in the ion to electron temperature ratio. © 2002 American Institute of Physics.
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  • 5
    ISSN: 1089-7674
    Quelle: AIP Digital Archive
    Thema: Physik
    Notizen: Research on the stability of spherical torus plasmas at and above the no-wall beta limit is being addressed on the National Spherical Torus Experiment [M. Ono et al., Nucl. Fusion 40, 557 (2000)], that has produced low aspect ratio plasmas, R/a∼1.27 at plasma current exceeding 1.4 MA with high energy confinement (TauE/TauE_ITER89P〉2). Toroidal and normalized beta have exceeded 25% and 4.3, respectively, in q∼7 plasmas. The beta limit is observed to increase and then saturate with increasing li. The stability factor βN/li has reached 6, limited by sudden beta collapses. Increased pressure peaking leads to a decrease in βN. Ideal stability analysis of equilibria reconstructed with EFIT [L. L. Lao et al., Nucl. Fusion 25, 1611 (1985)] shows that the plasmas are at the no-wall beta limit for the n=1 kink/ballooning mode. Low aspect ratio and high edge q theoretically alter the plasma stability and mode structure compared to standard tokamak configurations. Below the no-wall limit, stability calculations show the perturbed radial field is maximized near the center column and mode stability is not highly effected by a nearby conducting wall due to the short poloidal wavelength in this region. In contrast, as beta reaches and exceeds the no-wall limit, the mode becomes strongly ballooning with long poloidal wavelength at large major radius and is highly wall stabilized. In this way, wall stabilization is more effective at higher beta in low aspect ratio geometry. The resistive wall mode has been observed in plasmas exceeding the ideal no-wall beta limit and leads to rapid toroidal rotation damping across the plasma core. © 2002 American Institute of Physics.
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  • 6
    ISSN: 1089-7674
    Quelle: AIP Digital Archive
    Thema: Physik
    Notizen: The mission of the National Spherical Torus Experiment (NSTX) is to extend the understanding of toroidal physics to low aspect ratio (R/a(similar, equals)1.25) in low collisionality regimes. NSTX is designed to operate with up to 6 MW of high harmonic fast wave (HHFW) heating and current drive, 5 MW of neutral beam injection (NBI) and co-axial helicity injection (CHI) for noninductive startup. Initial experiments focused on establishing conditions that will allow NSTX to achieve its aims of simultaneous high βt and high-bootstrap current fraction, and to develop methods for noninductive operation, which will be necessary for Spherical Torus power plants. Ohmic discharges with plasma currents up to 1 MA and with a range of shapes and configurations were produced. Density limits in deuterium and helium reached 80% and 120% of the Greenwald limit, respectively. Significant electron heating was observed with up to 2.3 MW of HHFW. Up to 270 kA of toroidal current for up to 200 ms was produced noninductively using CHI. Initial NBI experiments were carried out with up to two beam sources (3.2 MW). Plasmas with stored energies of up to 140 kJ and βt=21% were produced. © 2001 American Institute of Physics.
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  • 7
    Digitale Medien
    Digitale Medien
    [S.l.] : American Institute of Physics (AIP)
    Physics of Plasmas 7 (2000), S. 1433-1436 
    ISSN: 1089-7674
    Quelle: AIP Digital Archive
    Thema: Physik
    Notizen: Toroidicity-induced Alfvén eigenmode (TAE) stability in the National Spherical Torus Experiment (NSTX) [S. M. Kaye, M. Ono, Y.-K. M. Peng et al., Fusion Technol. 36, 16 (1999)] is analyzed using the improved NOVA-K code [N. N. Gorelenkov, C. Z. Cheng, and G. Y. Fu, Phys. Plasmas 6, 2802 (1999)], which includes finite orbit width and Larmor radius effects and is able to predict the saturation amplitude for the mode using the quasilinear theory. A broad spectrum of unstable global TAEs with different toroidal mode numbers is predicted. Due to the strong poloidal field and the presence of the magnetic well in NSTX, better particle confinement in the presence of TAEs in comparison with tokamaks is illustrated making use of the ORBIT code [R. B. White and M. S. Chance, Phys. Fluids 27, 2455 (1984)]. © 2000 American Institute of Physics.
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  • 8
    Digitale Medien
    Digitale Medien
    [S.l.] : American Institute of Physics (AIP)
    Physics of Plasmas 4 (1997), S. 3667-3675 
    ISSN: 1089-7674
    Quelle: AIP Digital Archive
    Thema: Physik
    Notizen: The trajectories of neutral beam injected energetic ions in spherical tokamaks are examined. The large poloidal magnetic field in the outboard region of spherical tokamaks causes neutral beam injected ions to be born on trapped orbits even with cotangential injection. Numerical solutions to the equations for particle motion and for guiding center drifts are compared in several magnetic equilibria for a range of particle initial conditions. Even when rL/a∼1/4 the guiding center orbits closely resemble the path of the instantaneous center of gyration of the particle motion; exceptions occur primarily for orbits near the trapped/passing boundary. Finite Larmor radius effects are included in guiding center simulations of prompt orbit loss in the National Spherical Tokamak Experiment (NSTX) [J. Spitzer et al., Fusion Technol. 30, 1337 (1996)]. Orbit loss in the NSTX is caused primarily by collisions with the close fitting conducting shell, and severe losses would be expected with counter directed injection. While most orbits are similar to those found in conventional tokamaks, additional orbit types are possible in spherical tokamaks. © 1997 American Institute of Physics.
    Materialart: Digitale Medien
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  • 9
    Digitale Medien
    Digitale Medien
    [S.l.] : American Institute of Physics (AIP)
    Physics of Plasmas 3 (1996), S. 1667-1672 
    ISSN: 1089-7674
    Quelle: AIP Digital Archive
    Thema: Physik
    Notizen: Advanced tokamak configurations can have improved stability properties for high-n microinstabilities such as the toroidal drift mode (trapped-electron-ηi mode) and the kinetically-calculated magnetohydrodynamic (MHD) ballooning mode. A promising means to achieve this end involves employing tokamak configurations with very small aspect ratio, as in the proposed National Spherical Tokamak Experiment (NSTX) [M. Ono et al., Bull. Am. Phys. Soc. 40, 1655 (1995)] or the existing Small Tight Aspect Ratio Tokamak (START) experiment [R. J. Colchin et al., Phys. Fluids B 5, 2481 (1993)]. Kinetic instabilities are analyzed here using a comprehensive toroidal eigenvalue code with realistic equilibria for cases based on NSTX and START along with artificial cases to study parametric sensitivities. It is found that, as the aspect ratio decreases, the amount of "bad'' magnetic curvature decreases, causing stabilization of both electrostatic and electromagnetic high-n instabilities at sufficiently small aspect ratio. © 1996 American Institute of Physics.
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  • 10
    ISSN: 1089-7674
    Quelle: AIP Digital Archive
    Thema: Physik
    Notizen: Application of Ion Bernstein Wave Heating (IBWH) into the Princeton Beta Experiment-Modification (PBX-M) [Phys. Fluids B 2, 1271 (1990)] tokamak stabilizes sawtooth oscillations and generates peaked density profiles. A transport barrier, spatially correlated with the IBWH power deposition profile, is observed in the core of IBWH-assisted neutral beam injection (NBI) discharges. A precursor to the fully developed barrier is seen in the soft x-ray data during edge localized mode (ELM) activity. Sustained IBWH operation is conducive to a regime where the barrier supports large ∇ne, ∇Te, ∇νφ, and ∇Ti, delimiting the confinement zone. This regime is reminiscent of the H(high) mode, but with a confinement zone moved inward. The core region has better than H-mode confinement while the peripheral region is L(low)-mode-like. The peaked profile enhances NBI core deposition and increases nuclear reactivity. An increase in central Ti results from χi reduction (compared to the H mode) and better beam penetration. Bootstrap current fractions of up to 0.32–0.35 locally and 0.28 overall were obtained when an additional NBI burst is applied to this plasma. © 1995 American Institute of Physics.
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