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  • 1
    Electronic Resource
    Electronic Resource
    Desmoid Tumor of the Chest Wall Following Chest Surgery: Report of a Case (1999)
    Springer
    Surgery today 29 (1999), S. 945-947 
    Details
    ISSN: 1436-2813
    Keywords: Key Words: desmoid tumor ; chest wall ; chest surgery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s005950050545
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Desmoid tumor of the chest wall following chest surgery: Report of a case (1999)
    Springer
    Surgery today 29 (1999), S. 945-947 
    Details
    ISSN: 1436-2813
    Keywords: desmoid tumor ; chest wall ; chest surgery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Desmoid tumors of the chest wall following chest surgery are a rare occurrence. A case of this disease is reported herein together with a review of the literature. A 74-year-old man, who had previously undergone a right lower lobectomy for squamous cell carcinoma of the lung, was referred to our hospital with an abnormal shadow on his chest X-ray. The tumor, located in the right lateral chest wall, was successfully resected by an aggressive, wide extirpation, and a final diagnosis of a desmoid tumor originating in the chest wall was made. When following up patients after surgery for lung cancer, the possibility of desmoid tumors developing in the incised chest wall should therefore be kept in mind.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02482793
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Neurons with choline acetyltransferase immunoreactivity and mRNA are present in the human cerebral cortex (1999)
    Springer
    Histochemistry and cell biology 111 (1999), S. 197-207 
    Details
    ISSN: 1432-119X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract  We examined the cerebral cortex of five autopsied individuals without neurological and psychiatric diseases by immunohistochemistry using an anti-human recombinant choline acetyltransferase (ChAT) polyclonal antibody and in situ hybridization with 35S-labeled human ChAT riboprobes. The immunohistochemistry detected positive neurons which were medium-sized or large pyramidal neurons located predominantly in layers III and V. The density of such neurons was higher in the motor and secondary sensory areas than in other cortical areas; the immunoreactive neurons in layer V were more densely distributed in the motor area and those in layer III were distributed in the secondary sensory areas. Positively stained, non-pyramidal neurons were observed in the superficial layer of the cingulate gyrus and parahippocampus. No immunoreactive neurons were found in the primary sensory areas. The in situ hybridization detected some neurons with signals for ChAT mRNA in the cerebral cortex, most of which were distributed in layer V of the motor area and in layer III of the secondary visual area. These results indicate that the human cerebral cortex contains cholinergic neurons and displays regional and laminal variations in their distribution.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004180050349
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Immunohistochemical localization of collagenous proteins in cartilaginous tumors: characteristic distribution of type IX collagen (1993)
    Springer
    Journal of cancer research and clinical oncology 120 (1993), S. 35-40 
    Details
    ISSN: 1432-1335
    Keywords: Chondrosarcoma ; Enchondroma ; Collagen IX ; Immunohistochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The distinctive tissue localization of collagen types, particularly of type IX collagen in human cartilaginous tumors (10 cases of enchondroma and 15 cases of chondrosarcoma including 3 cases of secondary chondrosarcoma) was examined immunohistochemically using affinitypurified antibodies against types I, II, III, V, VI, and IX collagen, in comparison with that in human fetal cartilage. In fetal cartilage matrix, types II and IX collagen were diffusely distributed, while types I, III, and V collagens were not present. In the matrices of enchondromas and primary chondrosarcomas, types II and IX collagens were also diffusely distributed, but with some areas of irregular type IX collagen deposits. The secondary chondrosarcoma simulated normal fetal cartilage in the distribution pattern of types II and IX collagen, unlike the pattern in primary chondrosarcoma, where types II and IX collagen were decreased and poorly immunostained, whereas non-cartilaginous interstitial collagens (I, III, and V) appeared diffusely in the matrix, increasing with the grade of malignancy. These findings suggest that neoplastic cartilage is characterized initially by an uneven distribution of type IX collagen, prior to any alteration of other types of collagen; the diverse expressions of intercellular components in cartilaginous tumors may be one indicator for malignancy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01200722
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  • 5
    Electronic Resource
    Electronic Resource
    Case report of a patient with multiple lesions of the stomach, including multiple cancers and an adenomatous polyp (1995)
    Springer
    Journal of gastroenterology 30 (1995), S. 108-112 
    Details
    ISSN: 1435-5922
    Keywords: gastric polyp ; carcinoma in adenomatous polyp ; malignant transformation ; DNA ploidy pattern
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract This paper describes an unusual case of an 80-year-old man followed up for multifocal gastric cancers. There were three separate polypoid carcinomas and one adenomatous polyp with no sign of malignancy. We measured the DNA content of the gastric cancer and adenomatous cells obtained from endoscopically biopsied specimens. The adenomatous polyp and one of the cancerous lesions showed DNA diploidy. The other two cancerous lesions showed DNA aneuploidy, with different DNA index (DI) values (1.12 and 1.64, respectively). It is considered that the three cancers arose from different stem lines. However, an operation was not performed because the patient refused gastrectomy, and therefore only conservative follow up has been continued. Presentation of this case is followed by a detailed discussion focusing on the possible development of carcinoma in gastric adenomatous polyps in view of the data from the literature.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01211384
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  • 6
    Electronic Resource
    Electronic Resource
    Primary biliary cirrhosis associated with type A gastritis and chronic thyroiditis (1999)
    Springer
    Journal of gastroenterology 34 (1999), S. 415-419 
    Details
    ISSN: 1435-5922
    Keywords: Key words: primary biliary cirrhosis ; type A gastritis ; chronic thyroiditis ; iron deficiency anemia ; dry gland syndrome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract: We report a patient with primary biliary cirrhosis (PBC) associated with type A gastritis, chronic thyroiditis, and iron deficiency anemia. The patient was a 45-year-old Japanese woman who was admitted to our hospital with severe microcytic and hypochromic anemia, abnormal results for liver function tests, and a diffuse goiter. The diagnosis of PBC (Scheuer's stage II) was confirmed by the presence of specific anti-mitochondrial antibody in high titers and histological examination showing chronic non-suppurative destructive cholangitis with bridging fibrosis. Additionally, marked atrophic mucosa throughout the body and fundus of the stomach was observed endoscopically, and there was positivity for intrinsic factor antibody, an extremely low ratio of serum pepsinogen A to C, and hypergastrinemia, indicating coexisting type A gastritis. The severe anemia was thought to be caused by failure of dietary iron absorption related to achlorhydria with this gastritis. However, the serum level of vitamin B12 was normal. She also had autoimmune thyroiditis. PBC is frequently associated with extrahepatic autoimmune diseases, including ductular lesions. However, the association of PBC with type A gastritis is quite rare, although the stomach is also an exocrine glandular structure. This particular case, in addition to previous reports, leads to a discussion of whether type A gastritis should be regarded as a possible, although uncommon, component disorder of so-called dry gland syndrome.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s005350050286
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    Paper (German National Licenses)
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