Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    The effects of intraportal administration of prostaglandin E1 on liver ischemia and hepatectomy in rats (1998)
    Springer
    Journal of hepato-biliary-pancreatic surgery 5 (1998), S. 437-444 
    Details
    ISSN: 1436-0691
    Keywords: Key words: liver hemodynamics ; liver ischemia ; partial hepatectomy ; prostaglandin E1 ; reperfusion injury ; systemic arterial pressure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract: The effects of intraportal administration of prostaglandin E1 (PGE1) on portal venous flow, hepatic arterial flow, peripheral tissue blood flow, and systemic arterial flow before and after 60 min total liver ischemia followed by 70% partial hepatectomy in rats were investigated. Total liver ischemia was induced by occluding the hepatoduodenal ligament for 60 min. PGE1 at a dose of 0.5 μg/kg/min was infused intraportally for 15 min before inducing hepatic ischemia (preischemic period) and for 60 min after ischemia (postischemic reperfusion period) in the treatment group. Normal saline was infused in the control group. Seventy percent partial hepatectomy was performed during ischemia. Serum biochemical analysis and liver tissue histology were carried out 1, 3, and 24 h, and 1 and 24 h after reperfusion respectively. One-week survival of the PGE1 group was improved to 70% compared to that of the control group of 30%. Postischemia reperfusion values of portal and peripheral tissue blood flows in the PGE1 group were 6.33 ± 0.600 ml/min and 27.2 ± 23.5 (arbitrary), and were significantly different from those of the control group of 4.34 ± 0.400 ml/min and 23.5 ± 5.54 (arbitrary), respectively. There was no significant difference in hepatic arterial flow between the two groups. Serum alkaline phosphatase decreased significantly in the prostaglandin group. Histological examination revealed a significant portal venous congestion in the control group 1 and 24 h after reperfusion. The extent of the sinusoidal congestion was also severe in the control group 24 h after reperfusion. It was concluded that PGE1 has a protective effect against liver damage when the liver was injured by warm ischemia and reperfusion followed by partial resection.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s005340050069
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Melanin pigmented oncocytic metaplasia of the nasopharynx (1999)
    Springer
    Virchows Archiv 434 (1999), S. 455-457 
    Details
    ISSN: 1432-2307
    Keywords: Key words Melanin ; Oncocytic metaplasia ; Nasopharynx ; Electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  A 64-year-old man presented with a history of discomfort of the throat of a few weeks’ duration. Nasoscopic examination revealed multiple small, brown pigmentations at the left suprapharynx, the base of the left nasal cavity and the pharyngeal openings of the auditory tube on both sides. Microscopically, the lesion showed a glandular pattern of oncocytic epithelium with abundant pigmented granules and melanophages in the surrounding stroma. Immunohistochemically, the dendritic cells in the basal layer were positive for S-100 protein. Electron microscopic study revealed numerous fully melanized melanosomes and hypertrophied mitochondria in the oncocytic cells. Oncocytic cells do not produce melanin for themselves, melanin granules apparently being transferred from the adjacent dendritic cells to the oncocytic cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004280050366
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Ultrastructural findings in medulloepitheliomatous neoplasms induced by human adenovirus 12 in rodents (1974)
    Springer
    Acta neuropathologica 28 (1974), S. 293-304 
    Details
    ISSN: 1432-0533
    Keywords: Human Adenovirus Type 12 ; Medulloepitheliomatous Neoplasm ; Intracytoplasmic Inclusions ; Virion Particles ; Newborn Rodents
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Human-adenovirus-12-induced medulloepitheliomatous tumors from seven Sprague-Dawley rats, seven Syrian hamsters, and seven C3Hf/Bi mice were subjected to electron microscopic examination. A single intracerebral inoculation of 0.01 ml of human adenovirus fluid, 104.1 TCID50 HeLa cells/0.1 ml was made in the rats and hamsters within 24 hrs after birth, and a similar intraperitoneal inoculation was made in the C3Hf/Bi mice. Within 2 months, all rats and hamsters developed solid hemispherical neoplasms in close proximity to the cerebral ventricular system. The mice also developed multiple intraperitoneal neoplasms within almost the same latency period. Fixation was performed by whole-body perfusion. Examination revealed highly primitive tumor cells containing one cilium per cell, with a 9+0 pattern within the apical region. Intracytoplasmic myelin figures were prevalent in tumors in all three species. Intranuclear and intramitochondrial myelin figures were also common, while intramitochondrial rodlets were only occasionally seen. Virions of types A, B, and C were detected in both the Sprague-Dawley rats and C3H mice.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00685284
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Cellular monstrosity in embryonic neuronal neoplasm produced by human adenovirus in rats (1974)
    Springer
    Acta neuropathologica 30 (1974), S. 315-328 
    Details
    ISSN: 1432-0533
    Keywords: Human Adenovirus Type 12 ; Sprague-Dawley Rats ; Intracerebral Inoculation ; Medulloepitheliomatous Neoplasm ; Giant Tumor Cells ; Electron Microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Solid medullary brain and spinal cord neoplasms developed in all 10 offspring of an outbred Sprague-Dawley rat, between 37 and 99 days after a single postnatal (within 24 hrs) inoculation of 0.05 ml of human adenovirus type 12, 103.5–104.5 TCID50 HeLa cells/0.1 ml in the left frontal lobe. Seven rats developed multicentric neoplasms in both hemispheres and in peri-aqueductal areas of the brain stem, one of which was associated with an incipient spinal cord tumor in the sacral segment. One rat developed a solid tumor involving the right parieto-occipital region. The remaining two cases were solid spinal cord tumors arising from the dorsal half of the thoracolumbar segments. The remarkably uniform microscopic appearance was designated as a counterpart of human embryonic neuronal neoplasms. Characteristic neuronal and multinucleated giant cells emerged throughout the tumor tissue with argentaffine, neurofibril-like cytoplasmic expansions and a unique cilium (a 9+0 pattern of tubules) associated with a pair of centrioles. This cilium morphology was also a hallmark of the majority of tumor cells that formed characteristic pseudorosettes. The occasional emergence of two sets of cilia and centrioles in monstrous cells suggested probable modes of cytogenesis in relation to cessation of abnormal cell division.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00697014
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Comparison of University of Wisconsin and University of Pittsburgh solutions for heart transplantation (1996)
    Springer
    Transplant international 9 (1996), S. 380-385 
    Details
    ISSN: 1432-2277
    Keywords: Preservation, heart, rat ; Heart, preservation, rat ; UW solution, heart, rat ; Pittsburgh solution, heart, rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effectiveness of University of Wisconsin (UW) and University of Pittsburgh (UP) solutions for the preservation of rat hearts was compared. Lewis rat hearts were preserved with UW (group A, n=45) or UP (group B, n=45) solution for 0 or 24 h and then transplanted heterotopically into the recipients' abdomen. Ten recipients in each group were observed to obtain 1-week graft survival rates. Tissue water content and tissue content of adenine nucleotides were measured 2 h after transplantation in six grafts from each group. Six hearts preserved for 0 h and seven hearts preserved for 24 h were taken from each group 24 h after grafting for histopathology. The 1-week graft survival rates of groups A24 and B24 were 60% and 10%, respectively. In the 24-h preserved grafts, adenosine triphosphate (ATP) and energy charge [(ATP+adenosine diphosphate/2)/(ATP+adenosine diphosphate+adenosine monophosphate)] of groups A and B were 0.972±0.165 and 0.200±0.123 mg/g wet tissue (P〈0.05) and 74.4% and 61.1% (P〈0.05), respectively. The tissue water content of group A24 was 71.7%, whereas that of group B24 was 74.1% (P〈0.05). Histopathology revealed more severe muscle edema and necrosis and infiltration of polymorphonuclear cells in group B24 than in group A24. We conclude that UW solution is more appropriate for rat heart preservation than UP solution.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00335699
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    Extrapancreatic lymphoepithelial cyst of the pancreas (1996)
    Springer
    Journal of hepato-biliary-pancreatic surgery 3 (1996), S. 186-191 
    Details
    ISSN: 1436-0691
    Keywords: limphoepithelial cyst of the pancreas ; pancreas ; CA19-9
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A lymphoepithelial cyst is reported. A 68-year-old man consulted a surgeon, presenting with a sense of abdominal fullness. Ultrasonography and computed tomography revealed a large tumor, 10 cm in diameter, behind the head of the pancreas. Celiac arteriography at our hospital showed feeding arteries from the dorsal pancreatic artery and the pancreatic arcades. CA19-9 was elevated to 178 U/ml. Laparotomy was performed. The tumor was well demarcated from the surrounding tissue by a fibrous capsule and there was no continuity to the pancreatic parenchyma. Simple tumorectomy and distal gastrectomy for peptic gastric ulcer disease were performed. The cut surface revealed a multicystic lesion containing atheromatous substances. Histopathologically, the internal surface of the cyst was lined with stratified squamous epithelium containing mucin-producing cells; many germinal centers were observed in the cyst wall.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02350932
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...