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  • 1
    Electronic Resource
    Electronic Resource
    Lectin histochemistry as special markers for rodlet cells in carp, Cyprinus carpio L. (1990)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 13 (1990), S. 0 
    Details
    ISSN: 1365-2761
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2761.1990.tb00814.x
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  • 2
    Electronic Resource
    Electronic Resource
    Morphological Study of Metaphase-Specific Apoptosis in MRL Mouse Testis (2000)
    Oxford, UK : Blackwell Science, Ltd
    Anatomia, histologia, embryologia 29 (2000), S. 0 
    Details
    ISSN: 1439-0264
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Apoptosis of male germ cells is a complex phenomenon in many animal species. Understanding its mechanisms could be useful in the diagnosis and therapy of male infertility. To examine the differences of distribution of apoptosis among mouse strains, the terminal transferase-mediated nick end labelling (TUNEL) method was employed. In the testes of MRL mice, many TUNEL-positive cells were identified at the metaphases of meiotic spermatocytes. Morphometrical analysis revealed that metaphase-specific apoptosis occurred at the region between secondary spermatocytes and step 1 spermatids in stage XII seminiferous tubules. In the investigation of the developing first-wave of seminiferous tubules, there were some metaphases showing apoptotic morphology prior to becoming secondary spermatocytes. Details of the apoptotic structure revealed by electron microscopy showed that cellular arrest occurred after the beginning of the M phase of the cell cycle. These results suggested that metaphase-specific apoptosis in the testis of the MRL mouse strain took place at least at the first meiotic division, perhaps showing the spindle assembly checkpoint of the cell cycle.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1439-0264.2000.00279.x
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  • 3
    Electronic Resource
    Electronic Resource
    Expression of Angiotensinogen in the Uterus induced by Coagulating Gland Renin in Mice (1999)
    Oxford, UK : Blackwell Science, Ltd
    Anatomia, histologia, embryologia 28 (1999), S. 0 
    Details
    ISSN: 1439-0264
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Coagulating gland (CG) renin is one of the components of the local renin-angiotensin system (RAS), which plays important roles in the maintenance of homeostasis in several tissues. Although the existence of local renin has been reported in many tissues, its function is not yet well understood. In the present study, the relationship between CG renin and uterine angiotensinogen was investigated by immunohistochemical and in situ hybridization techniques. In mating experiments with male and female C57BL/6 mice, renin was demonstrated immunohistochemically on the epithelial cells of the uterus on the first day after coitus; however, it was not detected on the second and third days after coitus. Neither immunoreactive cells nor messenger signals for renin were demonstrated on the epithelial cells of the uterus throughout the experiments. On the first day after mating, it was noted that positive signals for angiotensinogen mRNA were expressed on the epithelial cells of the uterus in in situ hybridization, but not on the second and third days after coitus. These results suggest the possibility that CG renin is transferred to the uterine epithelium at mating and temporarily activates the expression of angiotensinogen in the uterus. Angiotensin II produced by angiotensinogen may act as an important mediator for vascularization of the first step of pregnancy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1439-0264.1999.00183.x
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  • 4
    Electronic Resource
    Electronic Resource
    Chemoreceptive Epithelioid Cells in the Chicken Aorta. An Electron Microscopical Study (1998)
    Oxford, UK : Blackwell Publishing Ltd
    Anatomia, histologia, embryologia 27 (1998), S. 0 
    Details
    ISSN: 1439-0264
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Aggregations of granulated epithelioid cells exist in the chicken aorta. In the present study, the locational characteristics of the epithelioid cells were investigated via an electron microscopic approach. Epithelioid cells were found mainly in two regions; the tunica interna just below the endothelial cell layers, and the intermediate region of the tunica media. In the former, the epithelioid cells were in contact with endothelial cells and sometimes directly exposed to the aortic lumen. No contact between the epithelioid cells and the nerve endings was observed in this region. On the other hand, in the intermediate region of the tunica media, five or more epithelioid cells were aggregated, and the cynaptic structures were occasionally observed. Additionally, the epithelioid cells in this region were observed to closely contact smooth muscle cells. In an experiment using horseradish peroxidase injection, reactions were detected in the intercellular spaces between the epithelioid cells and endothelial cells. These results suggest that the epithelioid cells localized in the subendothelial region receive information from the aortic lumen, whereas their aggregations in the tunica media are controlled by the nervous system.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1439-0264.1998.tb00174.x
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  • 5
    Electronic Resource
    Electronic Resource
    Vascularization and related distribution of leucocytes in carp, Cyprinus carpio L., head kidney (1990)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish biology 37 (1990), S. 0 
    Details
    ISSN: 1095-8649
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: The distribution of lymphoid cells in the carp head kidney was investigated in relation to the vascular system. Blood vessels in the head kidney were histologically identified into arteries, sinusoids and two types of veins: renal veins and portal, which were distinguished by India ink injection into the caudal vein. By histological and histoplanimetrical observations it was found that the head kidney contained a number of lymphoid cells, which mainly aggregate around the connections between the portal veins and sinusoids, and that the cellular density of the aggregations was higher than in the thymus.Pigment-containing cell clusters were also observed around these connections. This arrangement of the blood vessels suggests that it is one of the structures able to trap foreign materials, and the occurrence of the lymphoid clusters around the portal veins is a phylogenetic sign of the morphological division between granulopoietic and lymphatic tissues in the carp head kidney.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1095-8649.1990.tb05866.x
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  • 6
    Electronic Resource
    Electronic Resource
    An Immunohistochemical Study on the Embryonic Development of Renin-containing Cells in the Mouse and Pig (1989)
    Oxford, UK : Blackwell Publishing Ltd
    Anatomia, histologia, embryologia 18 (1989), S. 0 
    Details
    ISSN: 1439-0264
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The prenatal occurrence and distribution of renin-containing (RC) cells were investigated immunohistochemically in mouse and pig embryos.The RC cells of the mouse embryo were first observed at the 13th day of gestation at the walls of the renal, the mesonephric, the adrenal, the abdominal arteries, the adrenal glands and the testis. As the gestation of the mouse progressed, the RC cells had a tendency to localize in areas of the vascular pole of the metanephric glomerulus. In pig, when CRL was 0.8–2.0cm, RC cells first appeared at the ventral walls of the dorsal aorta, the omphalo-mesenteric (i.e., the cranial mesenteric), the mesonephric, the mesonephric afferent glomerular arteries/arterioles and the inside of the mesonephric glomenilus. As the length of the pig embryo increased, no renin-immunoreactivity could be demonstrated at the degenerated mesonephros, while in the metanephros marked immunoreactivities were found only at the terminal regions of intralobular arteries, i. e., afferent arterioles or the vascular pole of the glomerulus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1439-0264.1989.tb00576.x
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  • 7
    Electronic Resource
    Electronic Resource
    FRETTING FATIGUE OF AN AUSTENITIC STAINLESS STEEL IN SEAWATER (1994)
    Oxford, UK : Blackwell Publishing Ltd
    Fatigue & fracture of engineering materials & structures 17 (1994), S. 0 
    Details
    ISSN: 1460-2695
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract— Fretting fatigue tests of an austenitic stainless steel used for a propeller tail shaft were carried out in seawater and in air. In seawater, fretting significantly reduced the fatigue strength, however, the fretting fatigue lives at higher levels of stress were longer than those in air. The tangential force coefficient (defined as the ratio of the frictional force amplitude and the contact load) in seawater was much lower than that in air and varied in the range from 0.3 to 0.5 during the fretting fatigue tests. The lower tangential force coefficient in seawater seems to be the main reason for the longer fretting fatigue life in seawater. The prediction of fretting fatigue life was made on the basis of elastic-plastic fracture mechanics, where the frictional force between the specimen and the contact pad was taken into consideration. The predicted fatigue lives agreed well with the experimental results in both air and seawater.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1460-2695.1994.tb00824.x
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  • 8
    Electronic Resource
    Electronic Resource
    Renin in Exocrine Glands of Different Mouse Strains (1999)
    Oxford, UK : Blackwell Science, Ltd
    Anatomia, histologia, embryologia 28 (1999), S. 0 
    Details
    ISSN: 1439-0264
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The renin-angiotensin system (RAS) controls the regulation of blood pressure and water–mineral balance. Recently, renin has been reported to be synthesized and secreted outside the kidney. The present study investigated immunohistochemically the distribution of renin in exocrine glands, i.e. salivary glands and coagulating glands, in male mice of 13 strains. In some strains, renin was detected in the sublingual and submandibular salivary glands, but not in the parotid glands. It was restricted to the striated or granular portions of excretory ducts. In coagulating glands, variable staining patterns were found. These results demonstrate the existence of variations in renin content in mouse strains and offered a selection of mouse strains for investigation of exocrine gland renin.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1439-0264.1999.00197.x
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  • 9
    Electronic Resource
    Electronic Resource
    Expression of Renin in the Rat Liver (1998)
    Oxford, UK : Blackwell Publishing Ltd
    Anatomia, histologia, embryologia 27 (1998), S. 0 
    Details
    ISSN: 1439-0264
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Renin is well-known to be a trigger enzyme in the renin-angiotensin system (RAS). In contrast to the classical RAS, the local RAS has recently been noted in several tissues. The local RAS has a function independent from that of the classical RAS, although its physiological principles are not well known. In the present study, we immunohistochemically demonstrated that hepatocytes in the rat express renin. No renin-immunoreactive cells were detected in rat liver at 0 min after death. At 15 min after death, a small number of renin-positive cells was demonstrated in the lamina hepatica, and they increased with time to the end of observation. Immunoreactivity for renin was scarce throughout the cytoplasm, sometimes condensed to below the cell membrane and around the intracellular granules. Histoplanimetrically, the values from 15 min to 120 min after death were significantly different from that at 0 min after death. Hybridohistochemistry revealed no hybrid signals throughout the liver at either 0 min or 30 min, although renin-immunoreactivity was clearly demonstrated in adjacent sections of liver at 30 min after death. In RT-PCR, the radioactivities in kidney and liver at 0 min after death were not different from those at 30 min after death, respectively. These results suggest the existence of hepatic renin in the rat.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1439-0264.1998.tb00165.x
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  • 10
    Electronic Resource
    Electronic Resource
    Detection of Coagulating Gland Renin by Hybridohistochemistry (1996)
    Oxford, UK : Blackwell Publishing Ltd
    Anatomia, histologia, embryologia 25 (1996), S. 0 
    Details
    ISSN: 1439-0264
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: To obtain evidence of renin-synthesizing cells in the murine coagulating gland (CG), CG renin mRNA was detected by hybridohistochemistry. as well as in vitro reverse transcriptase-polymerase chain reaction (RT-PCR) in intact, castrated and testosterone-treated C57BL/6 mice. Hybridohistochemistry using paraffin sections of the kidneys and the CGs for the detection of renin mRNA was performed with digoxigenin-labelled probes. Some paraffin sections were immunohisto-chemically stained for renin by the peroxidase-anti-peroxidase method. Total RNA was extracted, incubated by reverse transcriptase, and amplified by PCR. In the kidneys, the immunoreactivity and the positive signals of hybridohistochemistry using an antisense probe were restricted to the same juxtaglomerular cells. In the control and at 7 days after testosterone administration to castrated mice, both renin-immunoreactivity and -hybridoreactivity were expressed by the epithelial cells in the CGs, while, in the CGs of the castrated mice and 3 days after testosterone injection of castrated animals, neither renin-immunoreactivity nor -hybridoreactivity was detected in the epithelial cells. Using RT-PCR, renin mRNA from the mice in the control and 7 days after testosterone injection of castrated was amplified, whereas, in the castrated and the 3 days after testosterone injection of castrated groups, it was not detected. The data presented here provide additional evidence that CG renin is regulated by testosterone.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1439-0264.1996.tb00094.x
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