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  • 1
    Electronic Resource
    Electronic Resource
    Facilitation of visuo-motor learning by transcranial direct current stimulation of the motor and extrastriate visual areas in humans (2004)
    Oxford, UK : Blackwell Science Ltd
    European journal of neuroscience 19 (2004), S. 0 
    Details
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Performance of visuo-motor tasks requires the transfer of visual data to motor performance and depends highly on visual perception and cognitive processing, mainly during the learning phase. The primary aim of this study was to determine if the human middle temporal (MT)+/V5, an extrastriate visual area that is known to mediate motion processing, and the primary motor cortex are involved in learning of visuo-motor coordination tasks. To pursue this, we increased or decreased MT+/V5, primary contralateral motor (M1) and primary visual cortex excitability by 10 min of anodal or cathodal transcranial direct current stimulation in healthy human subjects during the learning phase of a visually guided tracking task. The percentage of correct tracking movements increased significantly in the early learning phase during anodal stimulation, but only when the left V5 or M1 was stimulated. Cathodal stimulation had no significant effect. Also, stimulation of the primary visual cortex was not effective for this kind of task. Our data suggest that the areas V5 and M1 are involved in the early phase of learning of visuo-motor coordination.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1460-9568.2004.03367.x
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  • 2
    Electronic Resource
    Electronic Resource
    Qualitätssicherung in stationärer geriatrischer Versorgung – quo vadis? (1999)
    Springer
    Zeitschrift für Gerontologie + Geriatrie 32 (1999), S. 475-478 
    Details
    ISSN: 0044-281X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003910050145
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Eine neue Meßmethode des Rigiditätskoeffizienten (1960)
    Springer
    Graefe's archive for clinical and experimental ophthalmology 162 (1960), S. 78-96 
    Details
    ISSN: 1435-702X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung Es wird nach einem kurzen Literature-Überblick über Skleralrigidität ausführlich eine neue Methode zur Bestimmung des Rigiditätskoeffizienten dargelegt. Die Messungen werden mit dem Applanationstonometer allein unter Verwendung verschieden großer Prismen durchgeführt. Der mittlere Rigiditätskoeffizient wird geringgradig höher gefunden als der Durchschnittswert vonFriedenwald. Die halblogarithmische Formel zur Bestimmung wird für die klinischen Zwecke als ausreichend gefunden, gilt jedoch nicht bei stark erniedrigtem Druckniveau. Mit ansteigendem Druckniveau zeigt sich eine Abnahme der Rigidität. Daher soll bei Angaben von mittleren Rigiditätskoeffizienten auch der mittlere Tensionswert angegeben werden. Die Verteilungskurve der Rigiditätswerte ist symmetrisch.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00681995
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  • 4
    Electronic Resource
    Electronic Resource
    Experimenteller nachweis des molekulardispersen charakters der mischung von zwei polymeren und bestimmung des chemischen potentials in diesen mischungenHerrn Prof. Dr. G. V. Schulz zum 70. Geburtstag gewidmet (1976)
    New York : Wiley-Blackwell
    Die Makromolekulare Chemie 177 (1976), S. 1145-1160 
    Details
    ISSN: 0025-116X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Description / Table of Contents: With the aid of small-angle neutron scattering the molecularly disperse character of a clear mixture of two polymers in the absence of a low molecular weight compound is proved in one case and disproved in the other. If the mixture is molecularly disperse the chemical potential and the coil dimensions can be determined. Poly(methyl methacrylate) and styrene-acrylonitrile copolymers for certain compositions of the copolymer form molecularly disperse mixtures. They are exothermic, have a negative excess entropy of mixing and the coils are expanded as compared with the unperturbed coil dimensions. The theory of solubility parameters of Hildebrand and Scott enables one to find the miscible system, but the experimental second osmotic virial coefficients differ by an order of magnitude from those which could be estimated from this theory.
    Notes: Mit Hilfe der Neutronenkleinwinkelstreuung wird der molekulardisperse Charakter einer glasklaren Mischung von zwei Polymeren bei Abwesenheit eines niedermolekularen Lösungsmittels in einem Fall nachgewiesen, im anderen widerlegt. Falls eine molekulardisperse Mischung vorliegt, können das chemische Potential und die Knäueldimensionen bestimmt werden. Polymethylmethacrylat und Styrol-Acrylnitril-Copolymere bilden für gewisse Zusammensetzungen des Copolymeren molekulardisperse Mischungen. Sie sind exotherm, besitzen eine negative Exzeßentropie und die Molekülknäuel sind gegenüber den ungestörten Knäueldimensionen expandiert. Die Theorie der Löslichkeitsparameter von Hildebrand und Scott ermöglichte zwar die Auffindung des mischbaren Systems, aber die gemessenen zweiten osmotischen Virialkoeffizienten sind in der Größenordnung verschieden von denen, die nach dieser Theorie vorausberechnet werden können.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/macp.1976.021770415
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  • 5
    Electronic Resource
    Electronic Resource
    Enzyme engineering aspects of biocatalysis: Cofactor regeneration as example (1996)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 52 (1996), S. 309-319 
    Details
    ISSN: 0006-3592
    Keywords: cofactor regeneration ; amino acid ; chiral alcohol ; enzyme membrane reactor ; organic solvent ; biocatalysis ; Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Reaction engineering is an important tool in the case of cofactor depending enzyme-catalyzed reactions. It allows the establishment of conditions resulting in lower product specific cofactor costs as compared with product-specific enzyme costs. This is shown for the stereospecific reduction of carbonyl compounds yielding chiral amino acids and alcohols. In continuous processes, cofactor costs can be reduced if the cofactor can be retained within the bioreactor or recycled into it after separation of the product. In case of readily water-soluble substrates it is even possible to recycle the cofactor during a single pass through a continuously operated reactor more than 4000 times because normally very low cofactor concentrations are sufficient to saturate the enzymes involved. L-tert-Leucine has been produced by reductive amination with a space-time yield of up to 366 g L-1 d-1 in a single continuously operated enzyme membrane reactor and a two-stage cascade. Total turnover number of the cofactor NAD+ increased to 4230. (S)-1-Phenyl-2-propanol was obtained by reduction of the corresponding ketone in an membrane reactor with integrated extraction of the product. A new alcohol dehydrogenase from Rhodococcus erythropolis was used. A space-time yield of 63 g L-1 d-1 and a total turnover number of 1350 have been reached. L-Leucine has been produced using polymer-enlarged NADH. The total turnover number was 80,000 at a space-time yield of 214 g L-1 d-1. © 1996 John Wiley & Sons, Inc.
    Additional Material: 10 Ill.
    Type of Medium: Electronic Resource
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