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  • 1
    Electronic Resource
    Electronic Resource
    House dust mite allergen levels and an anti-mite mattress spray (natamycin) in the treatment of childhood asthma (1990)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 20 (1990), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Natamycin, a fungicide marketed as Tymasil, is claimed to reduce house dust mite numbers and would therefore be expected to improve asthma in children with mite sensitivity. We have tested this assertion by a double-blind, placebo-controlled trial. There was no significant effect on levels of Der p I in mattress dust between active and placebo groups at the end of the spraying period. Histamine inhalation challenge PC20, clinic visit symptom scores and lung function tests reflecting either large or small airways obstruction were also unchanged. Therefore this product is not a therapeutic option for mite-allergic patients using the manufacturer's recommended dose and method of administration. Other factors influencing the Der p I levels were also investigated. Of these, only month of measurement and bedroom wall humidity showed any association.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2222.1990.tb03150.x
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  • 2
    Electronic Resource
    Electronic Resource
    A rapid test for detection of mite allergens in homes (2002)
    Oxford, UK : Blackwell Science Ltd
    Clinical & experimental allergy 32 (2002), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background International guidelines recommend allergen avoidance for asthma management, but do not include making assessments of allergen exposure. Mite allergen exposure cannot be assumed, especially in geographical regions where climatic conditions vary.Objective To develop a rapid test that would enable consumers to detect mite allergen in the home.Methods A lateral flow test using gold labelled antibody for mite group 2 allergen was developed as part of a detection kit incorporating the MITEST dust sampling device. Dust samples were assayed by ELISA for group 1 and group 2 allergens and by using the rapid test. The tests were compared as indices of mite allergen exposure.Results There was a good correlation between group 1 and group 2 levels by ELISA (n = 349, r = 0.60, P 〈 0.001). In a multi-centre study of 65 homes (263 dust samples) in five countries, there was a strong correlation between ELISA and the rapid test. Most samples with high scores in the test (43/48, 90%) contained 〉 1 µg/m2 group 2 allergen, whereas most low samples contained 〈 1 µg/m2 (50/64, 78%). Differences between mean group 2 levels of samples that scored low (0.28 µg/m2), medium (1.68 µg/m2) or high (3.18 µg/m2) on the test were highly significant (P 0.007 to 〈 0.001).Conclusions A simple rapid test has been developed that detects mite allergen in the home within 10 min. The mite screening test should educate consumers about allergen exposure and encourage compliance with allergen-avoidance procedures. This technology has applications for the detection of other common environmental allergens.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2222.2002.01533.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    The control of allergens of dust mites and domestic pets: a position paper (1992)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 22 (1992), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2222.1992.tb01763.x
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Reduction of house dust mite allergen levels in the home: use of the acaricide, pirimiphos methyl (1985)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 15 (1985), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: House dust mite sensitivity is very common in patients with bronchial asthma, yet dust mite avoidance frequently receives little attention in clinical management. It is likely that any reduction in allergen levels associated with routine cleaning is insufficient to allow clinical improvement. In the present study the acaricide pirimiphos methyl is shown to reduce the levels of Dermatophagoides pteronyssinus, antigen P1 in homes. Following a single application the level of antigen P1 in dust from carpets was reduced by up to 73% and by more than 50% in soft furnishings. Serial sampling showed a reduction for 6 weeks under conditions where carpets and chairs treated with solvent showed a progressive rise in allergen level. Furthermore the survival of mites in cultures or infested carpet segments was markedly inhibited, with antigen PI accumulation reduced by 〉90%. These results suggest major reductions in house dust mite allergen levels in the home can be achieved.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2222.1985.tb02280.x
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  • 5
    Electronic Resource
    Electronic Resource
    A hapten-specific chimaeric IgE antibody with human physiological effector function (1985)
    [s.l.] : Nature Publishing Group
    Nature 314 (1985), S. 268-270 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The mouse plasmacytoma J558L secretes ? 1 light chains but does not produce an immunoglobulin heavy chain . The strategy used in the production of the recombinant IgE antibody was to introduce a plasmid that encodes a complete immunoglobulin e heavy chain into J558L and thus direct the production ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/314268a0
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  • 6
    Electronic Resource
    Electronic Resource
    Identification and field evaluation of the compounds comprising the sex pheromone of the female boll weevil (1979)
    Springer
    Journal of chemical ecology 5 (1979), S. 617-627 
    Details
    ISSN: 1573-1561
    Keywords: Sex pheromone components ; olfaction ; behavior ; female boll weevil ; Coleoptera ; Curculionidae ; Anthonomus grandis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract The terpenoid compounds (+)-cis-2-isopropenyl-1-methylcyclo-butaneethanol (I), (Z)-3,3-dimethyl-A-cyclohexaneethanol (II), and β-caryophyllene were isolated from frass of the female boll weevil (Anthonomus grandis Boheman). In laboratory bioassays, a mixture of these components attracted primarily males, whereas the male pheromone, grandlure, attracted primarily females. The addition to the cotton bud hydrocarbons, α-pinene, myrcene, andl-lim-nene, improved the response by males so that the potency of the mixture was comparable to that of grandlure for females. In field tests, I + II + hydrocarbons attracted both sexes, but grandlure alone and grandlure + hydrocarbons were more effective.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00987846
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  • 7
    Electronic Resource
    Electronic Resource
    A sex pheromone for male boll weevils from females (1977)
    Springer
    Journal of chemical ecology 3 (1977), S. 331-335 
    Details
    ISSN: 1573-1561
    Keywords: boll weevil ; Anthonomus grandis (Boheman) ; sex pheromone
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Steam distillation of frass of the female boll weevil,Anthonomus grandis Boheman, yielded an extract that was more attractive to males than to females in the laboratory. Extracts purified by TLC were attractive to males only. The active components appear to be alcohols and hydrocarbons.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00988448
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    Paper (German National Licenses)
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