Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Alpha-blocker test: Alternative to pressure–flow study of bladder outlet obstruction and detrusor contractility in patients without an enlarged prostate (2004)
    Melbourne, Australia : Blackwell Publishing Ltd.
    International journal of urology 11 (2004), S. 0 
    Details
    ISSN: 1442-2042
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract Objectives:  We investigated whether the cause of urinary disturbance in men with a prostate volume ≤20 mL can be determined by analyzing the efficacy of α1-adrenoceptor antagonist (alpha-blocker) treatment.Methods:  Thirty-five men who were 〉50 years of age, with an International Prostate Symptom Score (IPSS) ≥8 points, a quality of life (QOL) index ≥2 points and a prostate volume ≤20 mL were enrolled in the non-enlarged prostate group. Twenty-six men who met the above conditions but who had a prostate volume 〉20 mL served as controls. The α1-adrenoceptor antagonist tamsulosin was administered at a dose of 0.2 mg/day for 4 weeks. Results for the IPSS, QOL index, free flowmetry and pressure–flow studies were obtained before and after tamsulosin administration.Results:  In both groups, tamsulosin improved the IPSS and QOL index and the bladder outlet obstruction index (BOOI) was lowered without reducing the bladder contractility index (BCI). No parameter showed a significant difference in treatment efficacy between the two groups. In the non-enlarged prostate group, both the pretreatment BOOI and BCI correlated with the efficacy of treatment in improving maximum flow rate (Qmax). In the enlarged prostate group, BOOI and BCI did not correlate with Qmax. When Qmax was improved by ≥3.5 mL/s, the positive predictive value for both pretreatment BOOI 〉40 and BCI 〉100 was 100% in the non-enlarged prostate group.Conclusions:  The alpha-blocker test is one method to assess the presence of bladder outlet obstruction and the state of detrusor contractility in men without an enlarged prostate.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1442-2042.2004.00737.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Involvement of oxidative stress in the accelerated formation of pentosidine in patients with end-stage renal failure (1998)
    Oxford, UK : Blackwell Publishing Ltd
    Nephrology 4 (1998), S. 0 
    Details
    ISSN: 1440-1797
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: SUMMARY: Advanced glycation end products (AGEs) have been found to accumulate in the amyloid deposits, skin and plasma of haemodialysis patients (HD), implicating the possible involvement of AGE-modified protein in pathogenesis in dialysis-related amyloidosis. Pentosidine, an AGE cross-link, is a specific marker for AGEs. Plasma pentosidine levels in HD patients were increased dramatically. In the present study, plasma pentosidine, fructoselysine, advanced oxidation protein products (AOPP) and glutathione peroxidase (GSHPx) levels were measured to elucidate the role of oxidative stress in pentosidine formation in nondiabetic HD patients. Plasma pentosidine did not correlate with fructoselysine; plasma AOPP levels were significantly higher than those in normal subjects (201.45 ± 57.93 vs. 55.91 ± 6.57 μmol/L, P〈0.001) and correlated positively with plasma pentosidine in HD patients (r=0.52, P〈0.005); plasma GSHPx levels were significantly lower than those in normal subjects (168.40 ± 65.08 vs. 348.87 ± 86.10 U/I, P〈0.001) and correlated negatively with plasma pentosidine (r=0.54, P〈0.001) in HD patients. Decreased GSHPx levels may lead to the accumulation of hydrogen peroxide. These findings implicate the involvement of oxidative stress in the accelerated formation of pentosidine in uraemia and suggest that pentosidine could be considered as an oxidative stress biomarker to estimate the degree of oxidative-stress-mediated protein damage.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1440-1797.1998.tb00380.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Predialysis serum albumin concentration and creatinine generation rate do not reflect the same pathophysiologic status (1998)
    Springer
    Clinical and experimental nephrology 2 (1998), S. 44-49 
    Details
    ISSN: 1437-7799
    Keywords: nutrition ; mortality ; hemodialysis ; albumin ; creatinine ; nitrogen balance
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Background Whereas the creatinine generation rate may reflect only the protein nutritional status by way of muscle mass, the predialysis serum albumin concentration may well reflect a variety of aspects of a patient's pathophysiologic status, including the protein nutritional status. The aim of this study was to clarify whether or not serum albumin concentration and the creatinine generation rate reflect the same pathophysiologic status. Methods The risk of death associated with the creatinine generation rate was studied with and without adjustment for the serum albumin concentration in 1588 patients undergoing hemodialysis. A comparison was also made between the death risk associated with serum albumin concentrations with and without adjustment for the creatinine generation rate. Possible correlations between the creatinine generation rate and serum albumin concentration were evaluated. Results The death risk associated with the creatinine generation rate was little changed when adjusted for serum albumin concentration. However, the death risk associated with serum albumin concentration remained high even after being adjusted by the creatinine generation rate. Moreover, the correlation was very weak between the creatinine generation rate and the serum albumin concentration. Conclusions Serum albumin concentration and the creatinine generation rate do not reflect the same pathophysiologic status.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02480623
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Three-dimensional P-wave velocity structure in the upper crust beneath Kuju Volcano, central Kyushu, Japan (1998)
    Springer
    Bulletin of volcanology 60 (1998), S. 147-159 
    Details
    ISSN: 1432-0819
    Keywords: Key words Kuju Volcano ; 3D velocity structure ; Low/high velocity anomalies ; Negative Bouguer gravity anomaly ; Magmatic regime
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract  Kuju Volcano lies near Aso Caldera at the center of Kyushu Island, western Japan. After a few hundred years of dormancy, a phreatic explosion accompanied by a small ash eruption occurred on 11 October 1995. This study was undertaken to determine the subsurface seismic velocity structure associated with the active magmatic regime in the Kuju volcanic region. The three-dimensional, upper crustal, P-wave velocity structure beneath Kuju Volcano was determined using methods for the simultaneous inversion of P-wave arrival times from local earthquakes in and around the Kuju volcanic region for velocities and hypocentral parameters. Results reveal two shallower low-velocity anomalies located in the northern and southern parts of Kuju Volcano, consistent with the presence of significant negative Bouguer gravity anomalies. In addition, a high-velocity anomaly is located approximately 5 km northwest of Mt. Kuju, one of the domes in Kuju Volcano. Beneath this high-velocity anomaly, a low-velocity anomaly is present. This velocity structure suggests a magmatic regime that has a lid consisting of cooled solid material overlying a chamber of partially molten material.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004450050223
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Antioxidants inhibit TNFα-induced motility and invasion of human osteosarcoma cells: Possible involvement of NFκB activation (2000)
    Springer
    Clinical & experimental metastasis 18 (2000), S. 121-129 
    Details
    ISSN: 1573-7276
    Keywords: antioxidants ; invasion ; motility ; nuclear factor κB ; tumor necrosis factor α
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Osteosarcoma is the most frequent malignant bone tumor in children. It is highly invasive, however, the mechanisms behind osteosarcoma cell invasion are as yet still unknown. In the present study, treatment with TNFα enhanced the invasiveness of two human osteosarcoma cell lines, OST and MNNG. TNFα treatment also induced tumor cell motility, adhesion to laminin, the expression of matrix metalloproteinase 9 (MMP9), and the nuclear translocation of nuclear factor κB (NFκB) in the osteosarcoma cells. Moreover, antioxidants inhibited TNFα-induced osteosarcoma cell invasion, motility and NFκB nuclear translocation, but not adhesion to laminin or MMP9 expression. NFκB decoy, another NFκB inhibitor, also inhibited TNFα-induced osteosarcoma cell invasion and motility. Therefore, motility and NFκB activation were possibly related to TNFα-induced osteosarcoma cell invasion. However, adhesion to laminin or MMP did not demonstrate any correlation with TNFα-induced osteosarcoma cell invasion. Although NFκB is known to regulate TNFα-induced phenotypes, it may influence only motility and invasion, but not the MMP or laminin-mediated adhesion of these osteosarcoma cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1006791723233
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    An association-;based management of reusable software components (1998)
    Springer
    Annals of software engineering 5 (1998), S. 317-347 
    Details
    ISSN: 1573-7489
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract Processes to use environments which store reusable software components can be classified into “registration” (representation) and “retrieval” (remembering) processes. A conceptual space called “reuse space” is introduced which consists of the presentations of software entities and predicates to define the properties which the target entity should satisfy. The predicate parts are implemented by property definitions for entities, described with the language called HSML, and associative networks. The associative network is structured with using a psychological principle called category-;based induction. In the registration processes, nodes and links, which represent the new entity and the relationships with existing nodes, can be added to the associative networks. In the retrieval processes, the target entity can be remembered by searching the highest rating cluster in the associative networks with the aid of an inference engine. Clustering is performed with the use of coverages and proximities attached to the links in the network. The environment called MANDALA consists of user interfaces for displaying the reuse space on the client stations, a central web server and many distributed local servers which mount the contents of reusable components.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1018908004206
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 7
    Electronic Resource
    Electronic Resource
    Relationship between morphological diversity and AgNORs or cathepsin B expression in colorectal cancers (1996)
    Springer
    Journal of gastroenterology 31 (1996), S. 646-653 
    Details
    ISSN: 1435-5922
    Keywords: colorectal cancer ; morphological diversity ; flat type cancer ; AgNORs ; cathepsin B
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The biological characteristics associated with the morphological diversity of colorectal cancers were investigated to elucidate the causes of this diversity. We examined the proliferative and infiltrating activity of tumor cells, indicated by the mean number of Ag nucleolar organizer region associated proteins (NORs) per nucleus (MNA) and the immunohistochemical response to cathepsin B(CB), in various morphological types of early and advanced colorectal cancers. We examined 73 colorectal cancers obtained by endoscopic and surgical resection. MNA values for sessile and flat-elevated cancers were greater than the values for pedunculate, subpedunculate, and flat-or-depressed early cancers (sessile,P〈0.05). In advanced cancers invading the muscularis propria, protruding cancers showed significantly higher MNA values than small ulcerative cancers (P〈0.01). CB expression increased significantly with the progression of colorectal cancers (P〈0.01), but was not related to morphological diversity in early and advanced cancers. In both sessile and flat cancers, CB expression was higher in moderately differentiatiated than in well differentiated adenocarcinomas. These results indicate that, in colorectal cancers, protruding early cancers without stalks and protruding advanced cancers have higher proliferative activity than pedunculate or flat early cancers and small ulcerative advanced cancers, respectively, and that CB expression is not associated with morphological diversity, but with depth of invasion and histological differentiation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02347611
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 8
    Electronic Resource
    Electronic Resource
    An electroanalytical method for estimation of fish freshness using a flow-injection system with some immobilized enzyme reactors (1989)
    Weinheim : Wiley-Blackwell
    Electroanalysis 1 (1989), S. 173-176 
    Details
    ISSN: 1040-0397
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: A flow-injection system is proposed for the estimation offish freshness. The 5′-adenylic acid deaminase reactor, alkaline phosphatase reactor, and nucleoside phosphorylase-xanthine oxidase coimmobilized reactor were incorporated at fixed positions in a flow system, which was based on the splitting of the flow after sample injection and subsequent confluence before reaching the peroxidase electrode. Because each channel has a different residence time, two peaks were obtained. The first peak corresponded to the total of hypoxanthine and inosine, and the second peak to the total of hypoxanthine, inosine, inosine-5′-monophosphate, and adenosine-5′-monophosphate. The index of fish freshness, K, is estimated by \documentclass{article}\pagestyle{empty}\begin{document}$$ K = (S_2 /S_1)(i_1 /i_2)\,{\rm x}\,{\rm 100} $$\end{document} where s1 and s2 represent the sensitivity (nA mM-1) and i1 and i2 represent the peak current (nA) of the first and second peaks, respectively. The measurements could be performed at a rate of 15 samples per hour with satisfactory precision.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/elan.1140010214
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...