Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    facet.materialart.
    Unknown
    A Modified Continuation Method for the Numerical Solution of Nonlinear Two-Point Boundary Value Problems by Shooting Techniques (1976)
    Details
    Publication Date: 2020-03-06
    Language: English
    Type: article , doc-type:article
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    OPUS
  • 2
    Electronic Resource
    Electronic Resource
    Ätiologische Aspekte der Polyposis nasi et sinuum — vergleichende klinische, morphologische und immunologische Untersuchungen (1975)
    Springer
    European archives of oto-rhino-laryngology and head & neck 210 (1975), S. 350-350 
    Details
    ISSN: 1434-4726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Disorders of the immune system have been discussed as a possible cause of chronic sinusitis, but have up to date not been adequately substantiated. After the establishment of detailed case histories and clinical findings, samples of mucous membrane obtained by surgery from 50 patients with polyposis nasi et sinuum were examined histomorphologioally with respect to the intensity of edema, and the nature and extent of cellular infiltration. Parallel to this, the humoral immune reaction was determined by quantitative determination of the antibody-producing cells and the level of immunoglobulins in the tissue and serum. Histologically, all the preparations revealed a variety of marked stages of inflammation. The individual regions of mucosa manifested varying degrees of cellular infiltrations by lymphocytes and plasma cells. An immunological disorder in the form of an immune defect or a hypersensitivity reaction, corresponding to the histomorphological and clinical findings, was demonstrable only in a few individual cases.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00460074
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Wann ist eine Unterkieferresektion bei Mundhöhlen- und Oropharynxmalignomen angezeigt? (1981)
    Springer
    European archives of oto-rhino-laryngology and head & neck 231 (1981), S. 645-647 
    Details
    ISSN: 1434-4726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Cosmetic and functional disturbances are the result of any mandibular defect. Therefore the bone should not be resected, if not absolutely necessary. Out of 118 patients with tumours of the floor of the mouth and the tonsil, 24 patients with carcinoma very close to the mandible or attached to the periosteum, the tumour and bone were resected en bloc and histologically examined. According to our findings, the periosteum is a barrier, so that the tumor infiltrates the bone comparatively late. The histological results were in agreement with our surgical concept, which includes the following rules: 1. The mandibula can be preserved if the bone shows no infiltration after shaving of the periosteum. 2. A horizontal or vertical partial resection of the mandible is sufficient, if the tumor is adherent to the bone. The mandible may be preserved as a frame. 3. A complete segmental resection of the mandibula with secondary reconstruction is mandatory, if the tumour shows deeper infiltration into the bone.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00501687
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Meatoplastik mit allogenem, konserviertem Knorpel. Histomorphologische Modellstudie im Tierexperiment (1976)
    Springer
    European archives of oto-rhino-laryngology and head & neck 214 (1976), S. 135-142 
    Details
    ISSN: 1434-4726
    Keywords: Knorpeltransplantat ; Meatoplastik ; Tierexperiment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The reconstruction of the posterior wall of the external acoustic meatus destroyed by surgery or a cholesteatoma is necessary for the complete restoration of function. For this purpose, allogen cartilage preserved in thiomersalate has been transplanted on the anterior wall of the air-containing mastoid bone in 160 clinical cases. The histomorphological reaction of the recipient to unilaterally uncovered transplant material has previously been unknown. In 10 guinea pigs, 15 fenestrated bullae (hypotympanum equivalents) were closed with cartilage transplants fixed in place with tissue adhesive. After a period varying between 7 1/2 and 11 months, the walls of the bullae with the transplant were then examined histomorphologically. Despite the variations in the period in situ, the avital cartilage transplant, which remained largely constant in volume and shape, was always to be found. It was tolerated without reaction and was “enveloped” — also on the primarily uncovered surface — by a capsule of bone and connective tissue. In no case was rejection observed. Marked foreign-body reaction was, however, found in the vicinity of the tissue adhesive, which was absorbed only slowly. The clinically well-known tissue-compatible and complicationfree behaviour of the allogenic cartilage transplant preserved in thiomersalate, is thus explained by the histomorphological findings. In contrast, the fact that marked foreign-body reaction was demonstrable even after almost one year, suggests that tissue adhesive should not be used.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00453609
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Das chronisch-mechanische Trauma als wesentlicher Kofaktor in der Ätiologie von Mundhöhlenkarzinomen (1977)
    Springer
    European archives of oto-rhino-laryngology and head & neck 216 (1977), S. 559-560 
    Details
    ISSN: 1434-4726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In our series of 140 carcinomas of the oro-pharyngeal region smoking, alcohol abusus and diminished care of oral hygiene were obvious cofactors of cancer etiology. Most tumours were found in the lower social class. In contrast to other findings in the literature chronic mechanic trauma was frequent in our patients, resulting from sharp rests of teeth, insufficient conservation, or malfitting prosthesises. The epithelial lining showed, according to the clinical findings, histological inflammation, hyperkeratosis, carcinoma in situ or even growth of carcinoma. Therefore, optimal prosthesises and oral hygiene are important factors in the prevention of carcinomas of this region.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00458966
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    Das Ossifikationsprinzip der Trachealknorpel. Röntgenologisch-morphometrische und experimentelle Untersuchungen (1980)
    Springer
    European archives of oto-rhino-laryngology and head & neck 227 (1980), S. 457-458 
    Details
    ISSN: 1434-4726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The ossification of human tracheal cartilage is thought to be degenerative or due to genetic factors; in the final resort, however, its etiology still remains to be clarified. Therefore, on the one hand tracheal cartilages obtained from corpses of both sexes and various ages were X-rayed and subjected to measurements at defined points and, on the other hand, the relative distribution of stresses within tracheal cartilage was investigated in a model, using wire strain gauges, and evaluated with the aid of a computer. With increasing age, the cross-section of the tracheal cartilage at the sides and in the middle becomes greater, but to varying extents. Furthermore, in 50% of the males and in only 5% of the females, ossification with lamellar spongiosa occurs, primarily in the cranial and caudal outer margins of the ventral part of the cartilage ring. The cartilage, which is constantly subjected to tensile and compressive forces, reacts with an adaptive hypertrophy at that part of the inside of the cartilage that is exposed predominantly to compressive loading. As a result, the middle of the cartilage is markedly thicker than the sides. Under the influence of the compressive forces, the band-like traction effect of the collagen fibres in the ventral subperichondrial region of the tracheal cartilage becomes insufficient and the effects of stress on the cartilage greater. For a given stress level a greater extension results, which induces ossification in the region of its maximum effect — in the cranial and caudal convexity of the ventral part of the cartilage. In the region of ossification stabilization'occurs as a result of a change in the modulus of elasticity, so that the points subjected to the maximum extension force “migrate” laterally. In these sections, new bone is laid down until the tracheal cartilage has stiffened. The forces necessary to induce cartilaginous hypertrophy on the one hand, and insufficiency of the band-like traction effect on the other occur predominantly only in the male trachea. The ossification of tracheal cartilage is a further example of self-regulated adaptation of the connective and supportive tissues to mechanical stressing.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00467561
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 7
    Electronic Resource
    Electronic Resource
    Endoskopische Krebsnachsorge im oberen Aero-Digestiv-Trakt (1981)
    Springer
    European archives of oto-rhino-laryngology and head & neck 231 (1981), S. 656-659 
    Details
    ISSN: 1434-4726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Between 1975 and 1980, at the ENT Department of the University Hospital of Erlangen, more than 900 patients were treated for malignant lesions in mouth, pharynx and larnyx. About 40% of these lesions were laryngeal carcinomas. Long range after-care serves to ensure early recognition of residual, recurrent or second carcinomas. It rises particular demands with respect to organization and methods. Prerequisite is a good cooperation between patient and doctor. A tumour register in connection with a precise patient-summoning system, permits expedient patient follow-up at regular intervals. The ENT examination always includes endoscopy of the nose, pharynx and larynx in the awake patient. In addition to the routine photographic (and video-) documentation, a cytological swab is always obtained from the area of primary tumour manifestation. All visible proliferations are subject to a thorough cytological and histological (biopsy) investigation, irrespective of size or clinical significance. In the case of changes produced by irradiation or surgery, which can be difficult to evaluate, a different methodical approach may sometimes be required. Provided that the patient is properly instructed and is willing to cooperate, this standardized concept enables the detection of recurrences at an early stage — in particular in the larynx — and to ensure improved treatment with respect both to the functional result and the subsequent prognosis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00501693
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 8
    Electronic Resource
    Electronic Resource
    Symplectic phase flow approximation for the numerical integration of canonical systems (1992)
    Springer
    Numerische Mathematik 61 (1992), S. 501-521 
    Details
    ISSN: 0945-3245
    Keywords: 65L05 ; 65L07 ; 58F05 ; 70-08 ; 70F15 ; 70H15
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Summary New methods are presented for the numerical integration of ordinary differential equations of the important family of Hamiltonian dynamical systems. These methods preserve the Poincaré invariants and, therefore, mimic relevant qualitative properties of the exact solutions. The methods are based on a Runge-Kutta-type ansatz for the generating function to realize the integration steps by canonical transformations. A fourth-order method is given and its implementation is discussed. Numerical results are presented for the Hénon-Heiles system, which describes the motion of a star in an axisymmetric galaxy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01385523
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 9
    Electronic Resource
    Electronic Resource
    Osteointegration of different bone substitute materials in an experimental model (1998)
    Springer
    Der Orthopäde 27 (1998), S. 105-117 
    Details
    ISSN: 1433-0431
    Keywords: Key words Bone transplantation • Bone substitute • Ceramics • Osteointegration • Allograft ; Schlüsselwörter Knochentransplantation • Knochenersatzstoffe • Keramiken • Osteointegration
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Ziel der Untersuchung ist der Vergleich unterschiedlicher Knochenersatzstoffe hinsichtlich ihres Einwachsverhaltens im standardisierten Defektmodell des Kaninchenfemurkondylus. Bei 53 NZW-Kaninchen wurden insgesamt 105 zylindrische Bohrlöcher mit einem Durchmesser von 5,4 mm in jeweils beide Femurkondylen gesetzt und nach randomisierter Zuordnung mit kryokonservierter allogener Kaninchenspongiosa (n = 21), einer synthetisch hergestellten Hydroxylapatit (HA-)keramik (n = 21), korallinem HA-Granulat (n = 21) und oberflächenmodifiziertem Tricalciumphosphat (TCP) (n = 21) aufgefüllt. Bei der Kontrollgruppe (n = 21) verblieb der Substanzdefekt unaufgefüllt, um die spontane Knochenregeneration im gewählten Modell beurteilen zu können. Nach Tötung der Tiere erfolgte 2, 4, 6, 8, 12, 26 und 52 Wochen postoperativ die histomorphologische Untersuchung des Einwachsverhaltens sowie eine histomorphometrische Analyse an unentkalkten Methylmethacrylatdünnschnitten bzw. -schliffen. Die Ergebnisse zeigen in der Kontrollgruppe bei den meisten Tieren eine ausbleibende Knochenneubildung nach Leerlochbohrungen. Bei Applikation kryokonservierter Transplantate führt die initiale Anlagerung neugebildeten Knochens mit konsekutivem Umbau avitaler Bälkchen im Beobachtungszeitraum zu einem vollständigen Remodelling mit Wiederherstellung einer Spongiosaarchitektur, die dem unbehandelten Femurkondylus sehr ähnlich ist. Auch calciumphosphathaltige Knochenersatzstoffe und Implantate zeigen eine vollständige knöcherne Integration ohne Nebenwirkungen. Infolge der ausbleibenden Resorption kommt es jedoch im Verlauf der Untersuchung zu einer relativ hohen Volumendichte des Verbunds aus Prüfkörper und neugebildeter Spongiosa. Beim ausbleibenden Remodelling auch im ersatzstarken Lager des Kaninchens steht somit die langzeitstabile Keramik dem wünschenswerten Umbau zu einer trabekulären Spongiosaarchitektur, die auf modifizierte biomechanische Belastungen adäquat reagieren kann, im Weg.
    Notes: Summary In order to avoid the potential risks of disease transmission in allograft surgery, numerous substitute materials have been described. As the biological response to implant materials is different, we undertook the following study to assess type and amount of bone ingrowth in CaP-ceramics. 105 cylindrical bone defects with a diameter of 5.4 mm were created surgically in the femoral condyles of 53 sceletal mature NZW rabbits. The defects were filled with crushed coralline hydroxyapatite (HA) implants (n = 21), synthetically produced hydroxyapatite (n = 21) and surface-modified alpha-Tricalciumphosphate (TCP) grains (n = 21). 21 defects were left empty and other drill holes were filled with rabbit cancellous bone cylinders (n = 21) after 3 months of cryopreservation at –78 °C without sterilization. Following observation periods of 2, 4, 6, 8, 12, 26 and 52 weeks the femoral condyles were harvested for histological evaluation and quantitative analysis of bone ingrowth. Woven bone formation at implant periphery can be observed in all substances as early as 2 weeks postoperatively. At 4-week-intervals cryopreserved allografts show new bone apposition on surfaces of necrotic trabeculae and graft-host junctions by a predominantly osteoblastic reaction at the periphery of all cylinders, while in HA- and TCP-grains early bone formation in the center of drill holes is detectable as well. There is a direct contact between HA-/TCP-particles and newly formed bone without fibrous tissue formation at the implant surfaces. Central new bone formation in rabbit allografts can be observed after 6 to 8 weeks together with a secondary osteoclastic resorption of necrotic transplant trabeculae. The result of this remodeling process is a complete degradation of transplant cylinders with reorganization of vital trabeculae oriented in a mature pattern after 12 to 26 weeks. In contrast the HA- and TCP-implants did not show any signs of resorption.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/PL00003476
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 10
    Electronic Resource
    Electronic Resource
    Einflu\ von Mechanik und Alter auf den Spongiosaumbau in Lendenwirbelkörpern und im Schenkelhals (1977)
    Springer
    Virchows Archiv 377 (1977), S. 27-42 
    Details
    ISSN: 1432-2307
    Keywords: Quantitative morphometry ; Image analysing computer ; Spongy bone ; Lumbar vertebrae, neck of the femur ; Mechanical and agerelated changes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Bei 114 Verstorbenen beiderlei Geschlechtes im Alter von 31–97 Jahren ohne klinisch manifeste Knochenerkrankungen wurde der Einflu\ von Mechanik und Alter auf den Spongiosaumbau des 3. bzw. 5. Lendenwirbelkörpers und des rechten Femurhalses mittels des Leitz-Textur-Analyse-Systems quantitativ-morphometrisch untersucht. Die Auswertung erfolgte an Röntgenbildern 100 Μ dicker Knochenschliffe. Die volumetrische Dichte und OberflÄchendichte sind in den drei Knochen verschieden: am höchsten im Schenkelhals, am niedrigsten im 3. Lendenwirbelkörper und fast gleich niedrig im 5. Lendenwirbelkörper. Die volumetrische Dichte nimmt vom 30. bis zum 90., besonders nach dem 50. Lebensjahr gleichsinnig in allen drei Knochen um ein Drittel ab. Dementsprechend vermindert sich die OberflÄchendichte im 3. und 5. Lendenwirbelkörper ebenso um ein Drittel, wÄhrend sie sich im Femurhals nur um 18% reduziert. Die spezifische OberflÄche weist in den Lendenwirbelkörpern keine Altersunterschiede auf, im Schenkelhals dagegen steigt sie altersabhÄngig um 19% an. Die Konstanz der spezifischen OberflÄche in den Lendenwirbelkörpern erklÄrt sich nach der Reduzierung der volumetrischen Dichte mit Verlust von SpongiosabÄlkchen durch eine sekundÄre kompensatorische Hypertrophie der erhaltenen BÄlkchen. Dieser kompensatorische Knochenanbau findet im Femurhals nicht statt. Durch eine gleichmÄ\ige Abnahme des mittleren Durchmessers der KnochenbÄlkchen resultiert eine grö\ere spezifische OberflÄche, die der bei Osteoporose entspricht. Der gleichhohe, altersabhÄngige Spongiosaschwund der drei Knochen hat sich unter den verschiedenen Einflüssen des Druckes in den Lendenwirbelkörpern und der Biegung im Femurhals in einer für die einwirkenden mechanischen KrÄfte typischen Struktur der Restspongiosa manifestiert.
    Notes: Summary In 114 autopsy cases of both sexes, aged between 31 and 97 years and without bone disease, the influence of mechanical forces and age on the remodelling of spongy bone was determined using the third and fifth lumbar vertebrae and the neck of the right femur. For this purpose the Leitz texture analysis system (computer-aided) was employed. Evaluation was carried out with the aid of X-ray images of 100 Μ-thick polished bone slices. The volumetric density and the surface density vary in the three bones; they are highest in the neck of the femur, lowest in the 3rd lumbar vertebra, and almost as low in the 5th lumbar vertebra. The volume density decreases uniformly between the ages of 30 and 90 by about one third in all three bones, the decrease being particularly marked from the age of 50. Correspondingly, the surface density also decreases in the third and fifth lumbar vertebrae by one third, but only by 18% in the neck of the femur. The specific surface reveals no age differences in lumbar vertebrae, but increases by 19% with increasing age in the neck of the femur. The constancy of the specific surface in the lumbar vertebrae despite a decrease in the volumetric density with a loss of spongy trabeculae, can be explained by the fact that compensatory hypertrophy of the remaining trabeculae takes place. This compensatory growth of bone does not occur in the neck of the femur. As a result of the uniform decrease in the mean diameter of the bony trabeculae, a greater specific surface is found corresponding to values seen in osteoporosis. The age-dependent decrease in spongy bone, which is seen to a similar extent in all three bones, manifests itself in a structure of the residual spongiosa that depends on of compressive forces in the case of the lumbar vertebrae and bending forces in the neck of the femur.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00432696
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...