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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Applied microbiology and biotechnology 3 (1976), S. 43-54 
    ISSN: 1432-0614
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary Microbial oxidation and assimilation of n-tetradecane by two citric acid-producingCandida sp. (a wild typeCandida sp. KSH 21 and mutant from this strain No. 337) were studied. A monoterminal oxidation of n-tetradecane can be observed due to the isolation of 1-tetradecanol and myristic acid. Among the fatty acids detected from the culture fluid and in the cells the even-numbered dominate. No fatty acids with an odd number of carbon atoms could be isolated in the cells. A direct desaturation of myristic acid in the cells can be demonstrated by the presence of tetradecenoic acid. Beside monoterminal oxidation, diterminal oxidation can be observed by the appearance of tetradecanedioic acid. Dioic acids with an odd number of carbons can also be identified. Furthermore very many short chain dioic acids could be found in contrast to cultures grown on glucose and to other noncitric acid-producing species ofCandida. Substances which are supposed to be diols (1,14-tetradecanediol etc.) could be isolated in very small concentration from fermenter culture fluids of both strains.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Applied microbiology and biotechnology 8 (1979), S. 139-141 
    ISSN: 1432-0614
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary Four species of Streptomyces showed no or extremely slow and poor growth with the hydrocarbon as sole carbon source. They oxidize n-tetradecane by subterminal attack, two of them additionally by terminal attack, as determined by examination of the extracellular oxidation products. It is suggested that the organisms degrade the alkane mainly by cooxidation.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Naturwissenschaften 66 (1979), S. 373-376 
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 0138-4988
    Keywords: Life Sciences ; Life Sciences (general)
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Notes: Catabolic pathways of long-chain n-alkanes in the range of C8 to C18 are demonstrated and results of investigation about the regulation of monoterminal oxidation are given: - Enzymes of monoterminal alkane oxidation usually are inducible- Several intermediates of alkane oxidation can inhibit the primary oxidation of concerned alkane-Substances, e.g. glucose and glycerol, which ordinary don't be developed in catabolic alkane reactions, in many cases have an inhibitory effect on alkane oxidationThe regulation of catabolic pathways has a great influence on the formation of specific products This influence is demonstrated examplarily at the production of biotin, fatty acids and citric acid.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Berlin : Wiley-Blackwell
    Acta Biotechnologica 3 (1983), S. 279-288 
    ISSN: 0138-4988
    Keywords: Life Sciences ; Life Sciences (general)
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Notes: At the microbial oxidation of long-chain alkanes such monocarbonic acids at a monoterminal oxidation are formed which correspond to the chain length of the alkanes. At diterminal oxidation the corresponding dioic acids are produced.Under the influence of cerulenin a cerulenin a direct incorporation of fatty acids into cell lipids increases. Undecanoic acid cannot be metabolized byMortierella isabellina. It causes an inhibition of alkane oxidation. A main effect of undecanoic acid is an inhibition of the elongation of other fatty acids. The de novo fatty acid biosynthesis has not been inhibited by undecanoic acid.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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