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  • 1
    Electronic Resource
    Electronic Resource
    Adjuvant Vaccination in Colorectal Carcinoma (1993)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 690 (1993), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1993.tb44031.x
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  • 2
    Electronic Resource
    Electronic Resource
    237. Anwendungsmöglichkeiten des Diatrizoat-Pracipitationstestes in der Abdominalchirurgie (1974)
    Springer
    Langenbeck's archives of surgery 337 (1974), S. 871-871 
    Details
    ISSN: 1435-2451
    Keywords: Emergency Diagnosis ; Perforation ; Anastomotic Leakage ; Intensive Care ; Notfalldiagnosticum ; Perforation ; Nahtdehiszenz ; Intensivpflege
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung An 64 Patienten wurde durch gleichzeitige Röntgenuntersuchung die Zuverlässigkeit des Diatrizoat-(Gastrografin)-Pracipitationstestes im Harn bei Perforationen und Nahtdehiszenzen überprüft. Ein korrelierendes Ergebnis zwischen Test and Rontgen ergab sich bei 53 Patienten. Von 11 nicht korrelierenden Ergebnissen war bei 6 das Rontgen negativ, der Test aber positiv. Auf Grund des komplizierten postoperativen Verlaufes (Fieber, Fistel, später positives Rontgen) konnte eine rontgenologisch nicht nachweisbare Nahtdehiszenz angenommen werden. Fünf Fälle mit rontgenologisch nachgewiesenem Extravasat waren im Test negativ. Es handelt sich nach dem weiteren Verlauf um spontan heilende Fisteln bzw. Abscesse. Die Ergebnisse lassen den Diatrizoat-Teat bei: a) fehlendem Röntgen, b) immobilen Patienten (Intensivpflege), c) bei klinischem Verdacht auf Nahtdehiszenz bei negativem Röntgen, empfehlen.
    Notes: Summary The value of the diatrizoate-precipitation test for the diagnosis of intestinal perforation or suture line disruption was examined in 64 patients by simultaneous X-ray. In 53 cases correlation between the results of the test and the X-ray findings was seen. Of the 11 non-correlating results, 6 cases had negative X-ray but positive test results. Because of the complicated postoperative course (fever, fistula, later positive X-ray), we had to assume anastomotic leakage in these cases. Each of five patients with positive X-ray but negative test results had a spontaneously healing fistula or abscess. The results justify recommendation of the test (a) when X-ray examination is not available, (b) when a patient cannot be moved (intensive care), (c) when there is clinical suspicion of anastomotic leakage when X-ray is negative.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01278869
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  • 3
    Electronic Resource
    Electronic Resource
    Palliative and adjunctive measures in rectal cancer (1982)
    Springer
    World journal of surgery 6 (1982), S. 569-577 
    Details
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Cet article nous permet de relater notre expérience et celle de multiples auteurs en ce qui concerne les différentes méthodes thérapeutiques appliquées pour traiter le cancer du rectum: exérèse palliative, fulguration, cryo-chiruvgie, agents chimiques, encore qu'aucune étude comparative n'ait été entreprise pour apprécier leurs mérites respectifs. Dans notre série de 75 malades soumis à l'exérèse nous devons déploré une mortalité de 9,3%. Dans 88% des cas les symptomes présentés par le malade furent contrôlés cependant que la qualité de la vie fut satisfaisante jusqu'à leur décès. Le taux de la mortalité de la fulguration ne dépasse pas 0,5% mais les symptomes ne sont maitrisés que dans 40 à 80% des cas. Chez 219 malades soumis par nous mêmes à la cryo-chirurgie la mortalité fut de 2,3% cependant que le taux de la rémission atteignit 85%. La chimiothérapie a donné lieu à plusieurs études. D'après leurs données il semble que le cancer du rectum réponde mal aux différentes drogues cyto-toxiques qui ont été employées, le taux des rémissions s'étageant de 4 à 31% des cas traités.
    Notes: Abstract In this review we report our experience and that of others with palliative resection, fulguration, cryosurgery, and chemotherapy in rectal cancer. Since a trial has never been conducted to compare these procedures, it is not possible to give clear recommendations. In our study of palliative resection in 75 patients, we found an operative mortality of 9.3%. Tumor-related symptoms were controlled in 88%; the quality of life was good until death in most patients. Fulguration is reported to have a mortality rate of 0–5%, with control of symptoms in 40–80%, depending on tumor size. Cryosurgery was used in our series of 219 patients. Control of symptoms was achieved in 85% and the mortality rate was 2.3%. Side effects included unpleasant secretions for many weeks, bleeding, and stenoses. Chemotherapy has been tested in several studies. Colorectal cancer does not appear to be very sensitive to cytotoxic drugs, although numerous new substances have been tested over the past few years. Remissions have been achieved in 4–31% of patients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01657871
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  • 4
    Electronic Resource
    Electronic Resource
    Results of coloanal anastomosis. A prospective study (1986)
    Springer
    International journal of colorectal disease 1 (1986), S. 157-161 
    Details
    ISSN: 1432-1262
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Anterior resection with colo-anal anastomosis was carried out in 40 patients. The main indications were rectal neoplasia (30 cases) and irradiation proctitis (8 cases). Early complications occurred in 12 patients and three died of cardiopulmonary complications. Fistula formation and stenosis were the most frequent late complications. In 23 patients with adenocarcinoma operated for cure there was one recurrence. The functional results were good, although it often took up to 1 year until satisfactory continence, stool consistency and frequency were obtained. Manometry showed a significant decrease in anal canal length and resting tone postoperatively. The method is a practicable alternative to total rectal excision.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01648443
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  • 5
    Electronic Resource
    Electronic Resource
    Das Deviationsstoma (1999)
    Springer
    Der Chirurg 70 (1999), S. 650-655 
    Details
    ISSN: 1433-0385
    Keywords: Key words: Defunctioning stoma ; Loop colostomy ; Loop ileostomy ; Morbidity. ; Schlüsselwörter: Deviationsstomata ; Colostomie ; Ileostomie ; Morbidität.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung. Die Anwendung intestinaler Stomas zur Erhöhung der operativen Sicherheit bei colorectalen Eingriffen hat weite Verbreitung gefunden. Trotz Fortschritte in der operativen Technik sowie in der Stomaversorgung während der letzten 50 Jahre ist die Anlage eines Stomas immer noch mit einer beträchtlichen Morbidität vergesellschaftet, so daß die Notwendigkeit der Stomaanlage heute immer öfter kritisch in Frage gestellt wird. Der vorliegende Übersichtsartikel behandelt die Indikationsstellung, die chirurgische Technik sowie die Morbidität von Deviationscolostomie und -ileostomie.
    Notes: Summary. Intestinal stomas are widely used in the treatment of colorectal disease since they are relatively easy to construct and are supposed to increase the safety of colorectal surgery. During the past 50 years there have been several improvements in operative technique and stoma management but despite these advances there remains appreciable morbidity associated with the construction of stomas. Increasing awareness of the morbidity associated with enteral stomas has led to greater questioning of the need for temporary stomas. This paper reviews the indications and surgical technique as well as the morbidity associated with loop colostomy and ileostomy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001040050701
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  • 6
    Electronic Resource
    Electronic Resource
    Analer Schließmuskelersatz mittels dynamischer Gracilisplastik – Ergebnisse der Anwendung an 50 Patienten (1999)
    Springer
    Der Chirurg 70 (1999), S. 469-475 
    Details
    ISSN: 1433-0385
    Keywords: Key words: Sphincter restoration ; Fecal incontinence ; Abdominoperineal excision ; Dynamic graciloplasty. ; Schlüsselwörter: Schließmuskelersatz ; faecale Inkontinenz ; abdominoperineale Excision ; dynamische Gracilisplastik.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung. Von 1992–1998 wurden 50 Patienten einem Ersatz des analen Schließmuskels mittels dynamischer Gracilisplastik unterzogen, wobei eine primäre (n = 26) oder sekundäre (n = 6) totale anorectale Rekonstruktion nach abdominoperinealer Rectumresektion bzw. die erworbene (n = 9) oder angeborene (n = 9) faecale Inkontinenz die Indikation stellte. Bei 47 Patienten kam ein einzeitiges Verfahren unter Verwendung einer modifizierten Technik („split sling“) für die Muskelschlinge zur Anwendung. Durch Weiterentwicklung der Methode konnte das Stimulationsprogramm auf 4 Wochen verkürzt werden. Weiterhin hat sich die intraoperative Manometrie bewährt. Als gravierendste postoperative Komplikation wurde vor allem bei Patienten nach anorectaler Rekonstruktion (n = 8) eine Rectumarrosion bzw. -perforation beobachtet (n = 10). Entleerungsstörungen stellten sich bei Patienten nach anorectaler Rekonstruktion als hervorstechendes funktionelles Problem dar, wodurch die Kontinenzleistung negativ beeinflußt wurde. Diese Problematik konnte jedoch durch regelmäßige Einläufe behoben werden. Insgesamt konnte bei 80 % der Patienten mit faecaler Inkontinenz eine Verbesserung der Kontinenzleistung erreicht und bei 66 % der Patienten nach abdominoperinealer Rectumresektion die Anlage einer permanenten Colostomie verhindert werden.
    Notes: Summary. During the period from 1992 to 1998, 50 patients underwent anal sphincter restoration by dynamic graciloplasty for primary (n = 26) or secondary (n = 6) total anorectal reconstruction (TAR) following abdominoperineal rectal resection (APR) or acquired (n = 9) or congenital (n = 9) fecal incontinence, respectively. Forty-seven patients were operated on by a single-stage procedure using a modified technique for the muscle wrap (“split sling”). Muscle fiber transformation by controlled stimulation was achieved at the beginning of the learning curve within 8 weeks and in the meantime within 4 weeks. Rectal injury (n = 10) turned out to be the most serious postoperative complication and was observed mainly in patients following TAR (n = 8). As the most prominent functional problem constipation in patients following TAR hampered the postoperative functional result; however, this was overcome by regular enemas. An improvment in the continence status was observed in 80 % of the patients treated for fecal incontinence, and following APR 66 % of the patients had acceptable results without a permanent colostomy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001040050674
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  • 7
    Electronic Resource
    Electronic Resource
    Ein neues Verfahren zur zuverlässigen Dauerkanülierung des Ductus Choledochus am Hund (1975)
    Springer
    Research in experimental medicine 165 (1975), S. 297-300 
    Details
    ISSN: 1433-8580
    Keywords: common bile duct ; long term cannulation ; reliable method ; T-tube-protection by Thomas cannula ; Choledochus ; Langzeitkanülierung ; zuverlässige Methode ; T-Drain ; Schutz durch Thomaskanüle
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Es wird über eine neue Methode zur zuverlässigen Dauerkanülierung des Ductus Choledochus am Hund berichtet. Das Verfahren besteht darin, daß ein T-Drain herausgeleitet und für das Tier unerreichbar deponiert wird. Dies wird dadurch erzielt, daß das Drain in einer in die Baudecke implantierten Thomaskanüle aufgerollt wird. Das Ergebnis war bei bisher 9 Tieren sehr gut, die längste Kanülerungsdauer beträgt 9 Monate.
    Notes: Summary A new method for long term cannulation of the common bile duct in dogs is reported. The procedure is carried out with a T-tube, which is brought out through the abdominal wall. There it is rolled up in the hole of an implanted Thomas cannula. - A reliable protection from removal by the animal. The result in 9 dogs was very good, the longest duration of cannulation was 9 months.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01971390
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  • 8
    Electronic Resource
    Electronic Resource
    Regional gastric mucosal blood flow in hypovolemic shock (1979)
    Springer
    Research in experimental medicine 175 (1979), S. 181-185 
    Details
    ISSN: 1433-8580
    Keywords: Stress ulcer ; Regional mucosal blood flow ; Microspheres ; Hypovolemic shock ; Streßulcus ; regionale Schleimhautdurchblutung ; Mikrosphären ; hämorrhagischer Schock
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Der Effekt von Hypovolämie auf die Schleimhautdurchblutung von Corpus und Antrum des Rattenmagens wurde mittels der Mikrosphärenmethode 30 und 60 min nach Einleitung eines hämorrhagischen Schocks untersucht. Die Ergebnisse demonstrieren eine deutliche Herabsetzung ohne regionale Unterschiede zwischen Antrum und Corpus. Diese Minderdurchblutung korreliert eng mit der Senkung von Herzzeitvolumen und arteriellem Blutdruck. Regionale Unterschiede im Energiehaushalt der Schleimhaut, die als Erklärung für die im Corpus höhere Anfälligkeit für Stressläsionen herangezogen wurden, können nicht auf regional unterschiedliche Herabsetzung der Durchblutung zurückgeführt werden.
    Notes: Summary The effect of hypovolemia on the mucosal blood flow of the gastric corpus and antrum were tested with the microsphere method 30 and 60 min after induction of hemorrhagic shock in the rat. The results demonstrate a marked reduction after 30 and 60 min without any significant differences between the corpus and the antrum. This reduction is largely dependent on cardiac and circulatory function. It is concluded that the differences in energy metabolism, which have been implicated as explanation for the different susceptibility to develop stress lesions by Menguy and Masters, cannot be attributed to different degrees of ischemia.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01851825
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  • 9
    Electronic Resource
    Electronic Resource
    The electrically stimulated (dynamic) graciloplasty for faecal incontinence — first experiences with a modified muscle sling (1994)
    Springer
    International journal of colorectal disease 9 (1994), S. 184-186 
    Details
    ISSN: 1432-1262
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé La reconstruction sphinctérienne après excision totale du rectum au moyen d'un néosphincter fait d'un muscle gracilis stimulé donne des résultats sur le plan de la continence inférieurs à ceux obtenus en présence d'un canal anal intact. Nous décrivons une modification de l'anse alpha dans laquelle le tendon est fixé après avoir traversé la sangle de muscle gracilis. Les résultats de trois patients sont rapportés.
    Notes: Abstract Continence following the gracilis stimulated neosphincter reconstruction after total rectal excision is inferior to that obtained in the presence of an intact anal canal. We describe a modification of the alpha loop in which the tendon is brought through the belly of the gracilis muscle. The results in three patients are presented.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00292246
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  • 10
    Electronic Resource
    Electronic Resource
    Results of a rigorous follow-up system in colorectal cancer (1988)
    Springer
    International journal of colorectal disease 3 (1988), S. 176-180 
    Details
    ISSN: 1432-1262
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Results of a computer-aided follow-up programme for patients with colorectal cancer are analyzed. Between 1978 and 1987 1293 patients underwent this programme, the drop-out rate was 17%. 299 recurrences in 168 patients were discovered (40% local recurrence, 29% liver metastases and 31% others). Fifty-one per cent of patients with local recurrence and 47% with liver metastases were symptom free. Radical surgery could be performed in 50% of local recurrences and in 26% of liver metastases. The three year survival rate after radical surgery for recurrence was 35% for local recurrences and 33% for liver metastases, the five-year-survival rate 23% and 15%, respectively.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01648363
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