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  • 1
    Electronic Resource
    Electronic Resource
    Fatal complications after myelography with meglumine diatrizoate (1990)
    Springer
    Neuroradiology 32 (1990), S. 70-73 
    Details
    ISSN: 1432-1920
    Keywords: Intrathecal diatrizoate meglumine ; Lethal dysregulation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A case of inadvertent intrathecal injection of diatrizoate meglumine is presented. After myelography with 10 ml i.e. 6.5 g Angiografin, a 76-year-old man rapidly developed myoclonus, drowsiness and excessive metabolic acidosis. He died only a few hours later. Postmortem showed non-specific brain edema. RP-HPL-Chromatography confirmed high concentration of the contrast medium in CSF (6 mg/ml) which must have induced refractory central nervous dysregulation. The lethal effects of the misapplication of this agent on the nervous system are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00593948
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  • 2
    Electronic Resource
    Electronic Resource
    Akute tödliche Kupfervergiftung (1978)
    Springer
    Archives of toxicology 40 (1978), S. 263-267 
    Details
    ISSN: 1432-0738
    Keywords: Copper-intoxication ; Differential diagnosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Wenn eine akute Kupferintoxikation nicht durch den Kupfernachweis am asservierten Magen-Darminhalt gesichert wird, können sich differentialdiagnostische Schwierigkeiten ergeben. Es sollten hier der Morbus Wilson, der in seiner akuten abdominellen Form die klinische Symptomatik imitiert, sowie die symptomatischen Hypercuprämien ausgeschlossen werden. Dabei bietet sich neben den üblichen feingeweblichen und klinischen Untersuchungen zusätzlich die postmortale Kupferbestimmung im Hirngewebe an, die bei der Kupferintoxikation keine erhöhten Werte ergibt.
    Notes: Abstract If the diagnosis of copper-intoxication cannot be made by determination of copper in the collected specimen of the intestine, there may be problems in the differential diagnosis. In Wilson's disease and other cases of symptomatical hypercupriaemia copper content of brain tissues is elevated, while it is normal in acute copper intoxication.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00310331
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  • 3
    Electronic Resource
    Electronic Resource
    Suizidale Phosphorvergiftung (1979)
    Springer
    Archives of toxicology 42 (1979), S. 303-309 
    Details
    ISSN: 1432-0738
    Keywords: Phosphorus poisoning ; Suicide
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Akute Vergiftungen mit gelbem Phosphor sind im mitteleuropäischen Raum heute selten. Wir beobachteten eine suizidale Phosphorintoxikation. Der klinische Verlauf zeigte die klassischen drei Phasen mit einem symptomfreien Intervall. Bei dieser Vergiftung sind Form und Menge des aufgenommenen Phosphors für die enterale Absorption und somit für Prognose und klinischen Verlauf entscheidend. Gerade bei der Aufnahme auch größerer Mengen von Stangenphosphor scheint eine adäquate Therapie mit dem Grundprinzip der Absorptionsverhinderung sinnvoll.
    Notes: Abstract In central European countries phosphorus poisonings are rare today. A case of a suicidal intoxication with yellow phosphorus was studied. The clinical course showed the typical three stages including a symptom-free period, although death occurred within 50 h from acute toxic damage of the myocardium. The oral ingestion of phosphorus presents an emergency which demands immediate treatment. Prognosis is depending on the amount of phosphorus absorption in the intestine which is expected to be high if the poison is in a liquid vehicle.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00334845
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  • 4
    Electronic Resource
    Electronic Resource
    Acute fatal selenium poisoning (1986)
    Springer
    Archives of toxicology 59 (1986), S. 61-63 
    Details
    ISSN: 1432-0738
    Keywords: Acute selenium poisoning ; Normal selenium values ; Analytical procedure ; Industrial accident
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Neutralizing selenic acid with caustic soda caused a hyperintensive exothermic reaction, with about 450 1 of the reaction mixture erupting in a factory hall. A 44-year-old industrial worker was fatally intoxicated, suffering from second-degree skin burns, necrosis of oral mucous membranes and hemorrhagic lung edema. He died 90 min later. Analysis of body fluids and tissue samples showed high selenium concentrations in blood serum, urine, stomach content and lungs. The analytical results are discussed in comparison with normal selenium levels of non-exposed groups.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00263960
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  • 5
    Electronic Resource
    Electronic Resource
    Normal values of fluoride from a defined region of the human iliac crest (1975)
    Springer
    International archives of occupational and environmental health 35 (1975), S. 233-244 
    Details
    ISSN: 1432-1246
    Keywords: Fluoride ; Iliac Crest ; Ion-Selective Electrode ; Statistical Treatment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Normal fluoride concentrations in the human iliac crest are presented based on analyses of bone ash. Samples were obtained from 100 cadavers of both sexes. The bone samples were all taken from exactly the same skeletal location to allow for direct comparison with samples derived by bioptical methods from living subjects. The analyses were carried out on solutions of dried bone ash using an ion-sensitive electrode. Statistical treatment of the results shows a positive linear relationship between fluoride content and age.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01837098
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  • 6
    Electronic Resource
    Electronic Resource
    Forensic value of the Lugol's staining method: further studies on glycogenated epithelium in the male urinary tract (1994)
    Springer
    International journal of legal medicine 107 (1994), S. 147-151 
    Details
    ISSN: 1437-1596
    Keywords: Lugol's iodine ; Value-Forensic investigations ; Glycogenated epithelium cells ; Male urinary tract ; Lugol'sche Färbemethode ; Forensische Bedeutung ; Glykogenhaltige Epithelien ; Männlicher Harntrakt
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Description / Table of Contents: Zusammenfassung Wir untersuchten das Vorkommen glykogenhaltiger Epithelzellen im männlichen Harntrakt und an der Penisoberfläche, um die forensische Bedeutung der Lugol'schen Färbmethode für den Scheidenzellnachweis zu überprüfen. Das Untersuchungsmaterial bestand aus Abklatschpräparaten von Harnröhrenmündung, Glans Penis und Penisschaft sowie aus postmortalen Abstrichen aus der Fossa navicularis und histologischen Serienschnitten vom Penis. Polygonale, glykogenhaltige, Lugol-positive Epithelzellen waren regelmäßig im männlichen Harntrakt nachweisbar. Unsere Ergebnisse weisen darauf hin, daß diese Zellen aus der Fossa navicularis der Harnröhre stammen. Aufgrund einer möglichen Verschleppung abgeschilferter männlicher Epithelien an die Penisoberfläche, ist die Lugol'sche Färbemethode bei Penisabklatschpräparaten für den Scheidenzellnachweis ungeeignet.
    Notes: Abstract This study presents findings from a series of investigations on the presence of glycogenated epithelium in the male urinary tract and on the penile surface in order to assess the forensic value of the Lugol's method for the identification of vaginal cells. Direct smears obtained from the urethral opening, glans penis, and penile shaft, along with post-mortem samples of the fossa navicularis, and histological sections of the penis were examined. The presence of polygonal, glycogenated, Lugol-positive epithelium cells in the male urinary tract was found to be common. Our results suggest that these cells originate from the fossa navicularis. Because of the possibility of exfoliation of glycogenated male cells and transfer to the penile surface a Lugol-positive reaction in epithelial cells on penile swabs can no longer be assumed to prove the presence of vaginal cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01225602
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  • 7
    Electronic Resource
    Electronic Resource
    The value of the Lugol's iodine staining technique for the identification of vaginal epithelial cells (1994)
    Springer
    International journal of legal medicine 106 (1994), S. 298-301 
    Details
    ISSN: 1437-1596
    Keywords: Lugol's iodine staining technique ; Identification of vaginal cells ; Penile swabs ; Lugol'sche Färbetechnik ; Scheidenzellnachweis ; Penisabklatsch
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Description / Table of Contents: Zusammenfassung Wir untersuchten die Spezifität der Lugol'schen Färbetechnik für den Nachweis von Scheidenzellen in Penisabklatschpräparaten. Dazu wurde das luftgetrocknete Material von der Glans Penis von insgesamt 153 Klinikpatienten und 50 freiwilligen Probanden mit Lugol'scher Lösung gefärbt. Der letzte Geschlechtsverkehr lag jeweils mindestens fünf Tage zurück. Glykogenhaltige Plattenepithelien waren in mehr als 50% aller untersuchten Fälle nachweisbar, auch bei gesunden Probanden ohne Urethritis. In nahezu allen dieser Fällen waren im Penisabklatsch zumindest einzelne polygonale Epithelzellen mit eindeutig positiver Lugol-Reaktion nachweisbar. Diese Zellen lassen sich morphologisch nicht von superficialen oder intermediären Vaginalzellen unterscheiden. Harnwegsinfekte hatten keinen Einfluß auf den Glykogengehalt männlicher Epithelzellen. Unsere Ergebnisse zeigen, daß die Lugol'sche Färbetechnik für den Nachweis von Scheidenzellen in Penisabklatschpräparaten nicht mehr als geeignet angesehen werden kann.
    Notes: Summary This paper reports on the specificity of the Lugol's iodine staining technique for the detection of vaginal epithelial cells on penile swabs. Air-dried swabs taken from the glans of the penis of 153 hospital patients and from 50 healthy volunteers, whose last sexual intercourse had taken place at least 5 days previously, were stained with Lugol's solution. Glycogenated cells were found in more than 50% of the cases studied, even in healthy volunteers without urethritis. In almost all of these cases the smear contained at least a few polygonal nucleated epithelial cells showing an unequivocal positive Lugol reaction. These cells cannot be distinguished from superficial or intermediate vaginal cells, by cytomorphology or staining. Urinary tract infections had no influence on the glycogen content of male squamous epithelial cells. On the basis of these results the Lugol's method can no longer be assumed to prove the presence of vaginal cells in penile swabs.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01224775
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  • 8
    Electronic Resource
    Electronic Resource
    Differential diagnosis of postoperative liver failure in a 12-year-old child (1996)
    Springer
    International journal of legal medicine 109 (1996), S. 210-212 
    Details
    ISSN: 1437-1596
    Keywords: Fulminant hepatic dystrophy ; Paracetamol intoxication ; Enflurane anesthesia ; Hepatitis G virus infection
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Notes: Abstract The case of a 12-year-old child who died of fulminant hepatic failure a few days after tonsillectomy is reported. Histological examination revealed large areas of massive centrilobular hepatic necrosis. Hepatotoxity of postoperatively administered paracetamol in high dosages combined with enflurane exposure is discussed as a cause for the hepatic failure. The fulminant clinical course could have been influenced by an infection with hepatitis G virus which was detected in liver tissue by in situ hybridisation and was probably transmitted via transfusion of blood plasma.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01225520
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  • 9
    Electronic Resource
    Electronic Resource
    The syndrome of absent pulmonary valve and ventricular septal defect-anatomical features and embryological implications (1979)
    Springer
    Basic research in cardiology 74 (1979), S. 54-68 
    Details
    ISSN: 1435-1803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Das Syndrom der Pulmonalklappenaplasie mit Ventrikelseptumdefekt beinhaltet regelmäßig nicht nur eine hypo-dysplastische Pulmonalklappe und einen großen Ventrikelseptumdefekt, sondern zusätzlich auch Aneurysmen der Pulmonalarterien und ein Fehlen des Ductus arteriosus Botalli. Je nach dem Vorliegen oder Fehlen einer rechtsventrikulären Ausflußtraktobstruktion kann zwischen zwei Formen unterschieden werden. Fehlanlage der Pulmonalklappe, rechtsventrikuläre Ausflußtraktobstruktion sowie ein typischer Ventrikelseptumdefekt repräsentieren den primären Fehlbildungskomplex, welcher durch eine Septierungsstörung des Conotruncus verursacht wird. Daraus resultierendes intrauterines Herzversagen wird wahrscheinlich durch einen pränatalen Verschluß des Ductus arteriosus Botalli verhindert. Dilatation des rechtsventrikulären Ausflußtraktes und Entstehung von Pulmonalarterienaneurysmen sowie einige andere, häufig auftretende Deformitäten können dann durch diesen intrauterinen Ductusverschluß erklärt werden. Aus einer Analyse der dieses Syndrom aufbauenden, nur scheinbar unzusammenhängenden Einzeldeformitäten wird eine embryonische Entstehungstheorie abgeleitet.
    Notes: Summary Four cases of absent pulmonary valve in combination with ventricular septal defect are reported. In this syndrome hypo- and dysplasia of the pulmonary valve is constantly associated with a big ventricular septal defect, formation of a huge pulmonary artery aneurysm and absence of the ductus arteriosus. Presence or absence of a right ventricular outflow tract obstruction is the criteria for classification into two forms. Absence of the pulmonary valve, right ventricular outflow tract obstruction and a malalignment-type ventricular septal defect produced by a conotruncal malseptation process represent the primary complex of malformations. Consecutive intrauterine cardiac failure is most probably prevented by prenatal closure of the ductus arteriosus. Pulmonary artery aneurysm and also dilatation of the right ventricular outflow tract as well as a whole lot of other coexisting deformities can be explained by a cascade of hemodynamical sequelae started by this ductus closure in utero. An embryological scheme explaining the genesis of this syndrome is derived from a morphological analysis of the constituting incoherent-appearing anatomical features.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01907685
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  • 10
    Electronic Resource
    Electronic Resource
    Correlations of CT-findings and neuropathological investigations in cranio-cerebral trauma (1978)
    Springer
    International journal of legal medicine 82 (1978), S. 199-204 
    Details
    ISSN: 1437-1596
    Keywords: Computer-tomography, cranio-cerebral trauma ; Cranio-cerebral trauma, computer-tomography ; Computer-Tomographie, Schädelhirntrauma ; Schädelhirntrauma, Computer-Tomographie
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Description / Table of Contents: Zusammenfassung Um einen direkten Vergleich von Computer-Tomogrammen und Autopsiebefunden nach Schädelhirntraumen zu erreichen, wurden 86 formol- fixierte Gehirne entsprechend der horizontalen Schnittebenen des Computer- Tomogramms geschnitten und untersucht. In 72 % der Fälle fand sich eine hohe Übereinstimmung zwischen der neuen Rö ntgen-Untersuchungsmethode und den pathologisch anatomischen Vergleichspräparaten. Die Ursachen unzureichender Korrelierbarkeit der übrigen Fälle werden diskutiert.
    Notes: Summary For direct comparison of computerized tomograms (CT) and autopsy findings after cranio-cerebral trauma 86 brain specimes were sectioned along the horizontal planes of CT-scanning. A high reliability of the new x-ray method was found in about 72 % of the investigated cases. The causes of insufficient correspondence in other cases were discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02092336
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