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  • 1
    Electronic Resource
    Electronic Resource
    Renal handling of urate and oxalate: Possible implications for urolithiasis (1979)
    Springer
    Urological research 7 (1979), S. 143-148 
    Details
    ISSN: 1434-0879
    Keywords: Urate ; Oxalate ; Renal Handling ; Precipitation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Both urate and oxalate are organic acids of considerable clinical interest, owing to their limited solubility. Calcium oxalate is the most frequent constituent of renal calculi and occasionally precipitates in body fluids. Urate precipitations are common in the kidney and in various other tissues. In this paper, a short outline of the present knowledge of renal handling of these substances will be followed by some conclusions as to the possible relevance of this knowledge for the understanding of urolithiasis and intrarenal precipitation. Direct (micropuncture) data are available for urate in the rat (1,6, 7, 10, 21, 23, 28, 36, 42), rabbit (35), dog (34) and cebus monkey (33) and in the rat only for oxalate (11, 15, 20).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00257198
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Continuous in vivo measurement of plasma ionized calcium (1980)
    Springer
    Pflügers Archiv 384 (1980), S. 105-107 
    Details
    ISSN: 1432-2013
    Keywords: Ionized calcium ; thyropara-thyroidectomy ; ion selective electrode ; rat ; phosphate
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A new system for continous in vivo measurement of ionized calcium in blood is presented. The system consists of a small chamber (400 μl) which is thermostatized at 37°C and contains a glass electrode for pH measurement and a calcium selective electrode. The chamber is mounted in an arteriovenous shunt between the femoral artery and femoral vein of heparinized (approximately 1IU/min·kg B. W.) rats. The perfusion of approximately 500 μl/min is driven by blood pressure. The system is tested in rats undergoing acute thyroparathyroidectomy and phosphate infusion. Due to this procedure ionized calcium falls from 0.9 mmol/l (total calcium 2.0 mmol/l) to 0.35 mmol/l (total calcium 1.2 mmol/l) after 5 hours. Tetany then occurs in all animals. The system presented simplifies the measurement of ionized calcium and has the advantages of immediate and continuous recording. It is especially apt for small animals in which repeated measurements with standard techniques involve large blood losses.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00589523
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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