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  • 1
    Electronic Resource
    Electronic Resource
    Nabumetone Induces Less Gastrointestinal Mucosal Changes Than Diclofenac Retard (1999)
    Springer
    Clinical rheumatology 18 (1999), S. 273-278 
    Details
    ISSN: 1434-9949
    Keywords: Key words:Diclofenac – Efficacy – Endoscopy – Nabumetone – Osteoarthritis – Safety
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract: The aim of the study was to compare the efficacy and the effects on the mucosa of the gastrointestinal tract (GIT) of nabumetone and diclofenac retard in patients with osteoarthritis (OA). An open, multicentre, randomised, comparative, endoscopy-blind parallel group study included 201 patients with nabumetone and 193 patients with diclofenac retard suffering from moderate to severe OA of the knee or hip joint. Twelve clinical efficacy variables were assessed and a portion of the population underwent gastroduodenoscopy. All patients exhibited significant improvement in pain severity and pain relief (p50.001 and p50.0001, respectively) but there were no differences between the groups for all the efficacy variables. Eleven per cent of patients on nabumetone and 19% on diclofenac experienced GIT side-effects. Sixty-nine patients with nabumetone and 61 with diclofenac underwent gastroduodenoscopy. The differences in the mucosal grade for the oesophagus, stomach and duodenum at baseline were not significant. In the oesophagus there were significantly less changes after treatment with nabumetone (p = 0.007) than with diclofenac; there were similar findings in the stomach (p50.001) but the difference in the duodenum was not significant. This study indicates that nabumetone and diclofenac retard have similar efficacy in the treatment of OA, but nabumetone has significantly fewer GIT side-effects.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s100670050101
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  • 2
    Electronic Resource
    Electronic Resource
    Cyclophosphamide therapy in a patient with membranoproliferative glomerulonephritis and essential mixed cryoglobulinaemia (1998)
    Springer
    Clinical rheumatology 17 (1998), S. 395-396 
    Details
    ISSN: 1434-9949
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01450900
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Palindromic rheumatism in Israel — a disease entity ? A survey of 34 patients (1989)
    Springer
    Clinical rheumatology 8 (1989), S. 507-511 
    Details
    ISSN: 1434-9949
    Keywords: Palindromic Rheumatism ; Episodic Arthritis ; Rheumatoid Arthritis ; Negev ; Israel
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Over a period of 10 years 34 patients were diagnosed as suffering from palindromic rheumatism. Eightyone percent of the patients were of North African origin. This is significantly higher (p=0.01) than the ageadjusted origin of the general population in the region. Attacks were usually monoarthritic or oligoarthritic in nature. The joint most often involved was the knee. Prophylactic therapy with colchicine was ineffective. Gold salts brought about partial remission in three of six patients. Despite a relatively long average follow-up period of 9.3 years and the finding of a positive rheumatoid factor in 12% of the patients, not one of the patients developed rheumatoid arthritis. In 50% of the patients we detected an unexplained elevation in serum globulins and immunoglobulins. The possible association between this syndrome and Familial Mediterranean Fever is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02032105
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  • 4
    Electronic Resource
    Electronic Resource
    Systemic Sclerosis: Another Rheumatic Disease Associated with Hepatitis C Virus Infection (2000)
    Springer
    Clinical rheumatology 19 (2000), S. 378-380 
    Details
    ISSN: 1434-9949
    Keywords: Key words: HCV – Interferon – Systemic sclerosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract: The first case of a patient with chronic infection with hepatitis C virus who developed systemic sclerosis, manifested by severe Raynaud’s phenomenon, progressive skin thickening, painful fingertip ulcers, dysphagia and Sjogren’s syndrome, is described. The role of interferon therapy is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s100670070031
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Mud pack therapy in rheumatoid arthritis (1992)
    Springer
    Clinical rheumatology 11 (1992), S. 243-247 
    Details
    ISSN: 1434-9949
    Keywords: Rheumatoid Arthritis ; Mud ; Balneotherapy ; Dead Sea
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Twenty-eight patients with classical or definite rheumatoid arthritis were randomly divided into two groups of fourteen patients each. All patients were treated once a day with mud packs derived from the Dead Sea heated to 40°C and applied over the four extremities, neck and back for 20 minutes. Group 1 was treated with the true mud packs and Group 2 with washed out and less concentrated mud packs. The study was double blind and of two weeks duration. All patients were evaluated by one rheumatologist both before treatment and two weeks later at the end of the treatment period. Follow-up evaluations were made one and three months after conclusion of the treatment. The clinical indices evaluated included duration of morning stiffness, hand-grip strength, activities of daily living, patient's own assessment of disease activity, number of active joints and the Ritchie index. A statistically significant improvement (p〈0.01 or p〈0.05) was observed in Group 1 only in most of the clinical indices, lasting between 1 to 3 months.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02207966
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  • 6
    Electronic Resource
    Electronic Resource
    Polyarthritis associated with hydatid disease (Echinococcosis) of the liver (1992)
    Springer
    Clinical rheumatology 11 (1992), S. 286-287 
    Details
    ISSN: 1434-9949
    Keywords: Polyarthritis ; Reactive Arthritis ; Hydatid Cyst ; Echinococcus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A 36-year-old male developed asymmetric polyarthritis during the course of hydatid disease of the liver. Excision of the hydatid cyst was accompanied by full remission of the arthritis without recurrence during the 7-year follow-up period. This sequence of clinical events suggests an eventual cause and effect relationship. A “reactive” immune mechanism, triggered by a parasite located at a distant site, appears to be responsible for this type of arthritis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02207974
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    Cardiovascular manifestations of ankylosing spondylitis (1987)
    Springer
    Clinical rheumatology 6 (1987), S. 588-592 
    Details
    ISSN: 1434-9949
    Keywords: Ankylosing Spondylitis ; Cardiovascular ; Aortic Insufficiency ; Conduction Disturbances
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In a retrospective study, 40 patients with ankylosing spondylitis were assessed for extraspinal manifestations. Cardiovascular complications were found in 17 patients (42.5%)∶5(12.5%) had aortic insufficiency, 3 (7.5%) had atrioventricular block and 5 (12.5%) had bundle branch block. Wolff-Parkinson-White syndrome was diagnosed in one case and short PR syndrome in another. Cardiovascular complications were more common in patients with longer disease duration. Ischemic heart disease was found in 17.5% of the cases and pulmonary fibrosis in 15%. Peripheral arthritis was found in 42.5% and its prevalence did not differ in patients with or without cardiac involvement.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02330598
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    Paper (German National Licenses)
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