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  • 1
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Physics of Plasmas 4 (1997), S. 4301-4308 
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The motion of a plasma ion gyrating around the separatrix of a field-reversed configuration is studied. Numerical studies showed that the action integral of a particle changes abruptly when a particle passes through the vicinity of a field null x point. This phenomena is understood as collisionless stochastic scattering of the pitch angle. In the case of a particle with positive canonical angular momentum Pθ, the resultant correlation coefficients of the action integral between before and after the scattering appear to be stochastic in some cases. As the action integral increases for a particle with negative Pθ, its motion tends to be adiabatic. If the negative Pθ of a particle approaches zero, a stochastic motion is observed. © 1997 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    350 Main Street , Malden , MA 02148-5020 , USA and 9600 Garsington Road , Oxford OX4 2XG , England . : Blackwell Science Inc
    Journal of cardiac surgery 19 (2004), S. 0 
    ISSN: 1540-8191
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract  Objective: Cerebral complication is still a major concern in surgery for arteriosclerotic aortic arch disease. For preventing this complication, axillary artery cannulation, selective cerebral perfusion, and replacement of the ascending and arch aorta were applied to thoracic aortic aneurysm involving aortic arch. Method: From May 1999 to July 2002, consecutive 39 patients with true aneurysm (29 patients) or chronic aortic dissection (10 patients) involving aortic arch underwent replacement of the ascending and arch aorta with an elephant trunk under hypothermic cardiopulmonary bypass through the axillary artery cannulation and selective cerebral perfusion. The brain was continuously perfused without any intermission through the axillary artery. Concomitant operation included coronary artery bypass grafting (CABG) in two patients, aortic valve replacement (AVR) in one, Bentall operation in two, mitral valve replacement (MVR) in one, and aortic valve sparing operation in one. Patient age at operation was 40–84 (72 + 9) years and 24 of them were older than 70 years of age. Results: There was one operative death (2.5%) due to bleeding from the left lung, and one hospital death due to respiratory failure. Postoperative permanent neurological dysfunction was found in one patient (2.5%). Two patients presented temporary neurological dysfunction (5%). Thirty-six of the 39 patients were discharged from hospital on foot. Conclusion: Continuous perfusion through the axillary artery with selective cerebral perfusion and replacement of the ascending and arch aorta may minimize cerebral complication leading to satisfactory results in patients with chronic aortic aneurysm involving aortic arch.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1436-2813
    Keywords: CAD ; double cancers ; concomitant surgery ; CABG
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Concomitant surgical procedures for coronary artery disease and double cancers are reported. A 61-year-old man with severe triple-vessel coronary disease was found to have early gastric cancer and advanced rectal cancer. We successfully performed a concomitant coronary artery bypass graft using an extracorporeal ultrafiltration membrane and curative surgery for both cancers. Concomitant surgery thus appears to be a benefical and safe approach for the treatment of critical coronary artery disease and intraperitoneal double cancers in carefully selected patients.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1436-2813
    Keywords: Key Words: median sternotomy ; C-reactive protein ; minimally invasive direct coronary artery bypass
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: vs 66 ± 8 years old, the operative time, being 321 ± 149 vs 441 ± 205 min, the number of grafts, being 1.0 vs 1.4/patient, peak creatine kinase (CK) values, being 662 ± 436 vs 609 ± 56 IU/l, the peak CK-muscle-brain values, being 12 ± 9 vs 16 ± 5 IU/l, and the postoperative blood loss, being 369 ± 198 vs 541 ± 204 ml. Although there was no significant difference in peak C-reactive protein, at 17 ± 5 vs 20 ± 2 mg/dl, the periods declining within the normal ranges were shorter in the MIDCAB group than in the off-pump group, at 7 ± 1 vs 15 ± 2 days (P 〉 0.01). The hospital stay was almost the same in both groups, at 16 ± 8 vs 26 ± 14 days. These findings suggest that off-pump bypass is more invasive than MIDCAB, which may be attributed to the median sternotomy.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1436-2813
    Keywords: coronary artery disease ; cancer ; coronary artery bypass grafting ; concomitant surgery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The surgical management of patients with concomitant critical coronary artery disease (CAD) and surgically resectable cancer is controversial. We evaluated 19 patients who underwent concomitant coronary artery bypass grafting (CABG) and curative operation for cancer of the stomach in 9 patients, the colon in 4, the lung in 4, and the breast in 2. Each cancer operation was performed under stable hemodynamics without any serious bleeding tendency, immediately after CABG with an average of 2.5±0.8 grafts. There were no operative deaths and no incidences of perioperative myocardial infarction. Postoperative complications developed in three of the patients with lung cancer: respiratory dysfunction caused by phrenic nerve paralysis in two and mediastinitis in one. During the mean follow-up period of 33±23 months, 5 patients died of recurrent cancer or non-cardiac disease; however, all 19 patients remained free from any postoperative cardiac events and their quality of life apparently improved. This experience suggests that such simultaneous correction would be safe and beneficial in carefully selected patients who have surgically correctable CAD and potentially curable cancer.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Parmi les 26 patients qui avaient eu un pontage coronarien associé à une chirurgie abdominale dans notre institution entre 1977 et 1992, neuf avaient une maladie coronarienne sévère associée à un cancer gastrique stade I UICC. Le pontage coronarien a été suivi d'une gastrectomie à visée curatrice soit en un (premier dans l'ordre chronologique, groupe A=4), soit en deux temps (groupe B=5). La chirugie cardiaque a précédé la chirurgie gastrique dans tous les cas, et dans le groupe B, l'intervalle entre les deux interventions a été de 2 à 7 semaines. Il n'y avait aucune différence significative entre les deux groupes en ce qui concerne l'âge, le sexe, l'état préopératoire, la classification NYHA, les antécédents d'infarctus du myocarde, la fraction d'éjection, l'indexe cardiaque, le nombre de vaisseaux atteints ou le nombre de greffons utilisés. Il n'y avait aucune différence entre les deux groupes en ce qui concerne la perte sanguine pendant l'intervention gastrique (A: 649±194 ml; B; 842±326 ml) ou la durée de l'intervention (A: 371±106 min; B: 343±46 min). Deux patients dans le groupe A ont eu une complication postopératoire (un cas d'arythmie, et un autre cas, fatal, de fuite anastomotique). Il y a eu quatre complications chez les patients du groupe B (trois cas d'hyperbilirubinémie transitoire, un cas d'hémorragie postopératiore, sans aucune mortalité). La durée d'hospitalisation postopératoire n'a pas été significativement plus longue chez les patients du groupe B (A: 41.7±22.7 jours; B: 46.0±25.0 jours). En conclusion, la chirurgie coronarienne et gastrique peut être faite simultanément avec sécurité, mais une surveillance et une thérapeutique périopératoire rigoureuse sont nécessaires.
    Abstract: Resumen De 26 pacientes sometidos tanto a “bypass” coronario y a cirugía abdominal en nuestra institución entre 1977 y 1992, 9 exhibían severa enfermedad coronaria asociada con cáncer gástrico en estadío I (UICC). Estos casos fueron tratados con “bypass” coronario seguido de operación curativa para su cáncer gástrico; los primeros 4 pacientes recibieron cirugía en dos etapas (Grupo A), en tanto que los últimos cinco pacientes recibieron cirugía simultánea (Grupo B). La cirugía cardíaca fue realizada primero en todos los pacientes, y en los del Grupo A el intervalo entre los dos procedimientos fue de 2–7 semanas. No se encontraron diferencias significativas entre los dos Grupos en cuanto a características preoperatorias: sexo, edad, complicaciones preoperatorias, clase NYHA (New York Heart Association), infarto miocárdico previo, fracción de eyección, índice cardíaco, número de vasos afectados o número de injertos. No se hallaron differencias significativas entre los dos Grupos en cuanto a pérdida de sangre durante la operación gástrica (A: 649±194 ml; B: 842±326 ml) o el tiempo operatorio (A: 371±106 min; B: 343±46 min). Dos pacientes del Grupo A presentaron complicaciones postoperatorias (1 caso de arritmia, y 1 murió de sepsis por falla de la sutura). Por el contrario, 4 pacientes del Grupo B desarrollaron complicaciones (3 casos de hiperbilirrubinemia y 1 caso de hemorragia postoperatoria: ninguno murió). La estancia postoperatoria después de la gastrectomía no resultó prolongada en el Grupo B, en comparación con el Grupo A (A: 41.7±22.7; B: 46.0±25.0 días). En conclusión, se pueden realizar en forma segura el procedimiento de “bypass” coronario y de cirugía gástrica, aunque es indispensable un cuidadoso manejo del paciente.
    Notes: Abstract Or 26 patients who underwent both coronary artery bypass grafting and abdominal surgery at our institution between 1977 and 1992, nine had severe coronary artery disease associated with UICC stage I gastric cancer. They were treated by coronary artery bypass grafting followed by a curative operation for gastric cancer, the initial four patients underwent two-staged surgery (group A), and the most recent five patients underwent simultaneous surgery (group B). The cardiac surgery was performed first in all patients, and in group A the interval between the two procedures was 2 to 7 weeks. There were no significant differences between the two groups in terms of preoperative characteristics: sex, age, preoperative complications, NYHA class, prior myocardial infarction, ejection fraction, cardiac index, number of vessels diseased, or number of grafts. There were no significant differences between the two groups in terms of blood loss during the gastric operation (A: 649±194 ml; B: 842±326 ml) or the operating time (A: 371±106 minutes; B: 343±46 minutes). Two group A patients had postoperative complications (one had arrhythmia, and one died of sepsis caused by sutural insufficiency). On the other hand, four group B patients had complications (three cases of transient hyperbilirubinemia and one case of postoperative bleeding: none died). The postoperative hospital stay after gastrectomy was not prolonged in group B compared with group A (A: 41.7±22.7 days; B: 46.0±25.0 days). In conclusion, simultaneous procedure of coronary artery bypass grafting and gastric surgery can be performed safely, although careful management is indispensable.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-0843
    Keywords: Key words UFT ; Compliance ; Adjuvant chemotherapy ; Colorectal cancer
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Purpose: When oral anticancer agents are used for adjuvant chemotherapy of colorectal cancer, compliance and feasibility become issues because of the long treatment time. Appropriate studies of these issues are lacking. We investigated compliance and feasibility during a weekday-on/weekend-off schedule of oral UFT (uracil-tegafur) over a period of 1 year administered as adjuvant chemotherapy to patients with colorectal cancer. Patients and methods: A UFT dose of 600 mg/day was prescribed according to a weekday-on/weekend-off schedule to 87 patients after potentially curative resection. Compliance was investigated in three ways: physician interview, patient self-report, and chemical analysis of urine. The results were compared with the dose prescribed. Feasibility was evaluated on the basis of two indices: relative performance (RP), which was the ratio of the actual total dose taken to the total dose planned, and individual dose intensity (IDI), which was the ratio of the actual dose taken to the dose planned during a given period. Results: The compliance assessed by physician interview and by patient self-report conformed well with the prescribed dose, the rate of agreement among the three compliance measures being more than 94%. Chemical analysis of urine in 38 of the patients revealed that they were actually taking the drug. The RP was 0.72, and the IDI was 0.8. Conclusion: From these results, the feasibility of the weekday-on/weekend-off schedule was judged to be good. It is suggested that the feasibility would be even better if the dose of UFT was set according to body surface area.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Zeitschrift für die chemische Industrie 100 (1988), S. 1777-1779 
    ISSN: 0044-8249
    Keywords: Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Angewandte Chemie International Edition in English 27 (1988), S. 1711-1713 
    ISSN: 0570-0833
    Keywords: Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
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